There has been a surge of interest in diffuse optical tomography (DOT) that uses near-infrared light to detect, localize and diagnose maladies such as breast cancer and brain injury. Scattering and light attenuation limit the resolution and accuracy of DOT methods that use small differences in optical properties to distinguish lesions from normal tissue. Researchers need a DOT approach that can, for example, quickly reconstruct images to detect and map tumors at early growth stages and determine if they are malignant or benign.

© 2012 Optical Society of America

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