Abstract

In this Letter we propose a method to enhance the limited depth of field (DOF) in optical imaging systems, through digital holography. The proposed approach is based on the introduction of a cubic phase plate into the diffraction integral, analogous to what occurs in white-light imaging systems. By this approach we show that it is possible to improve the DOF and to recover the extended focus image of a tilted object in a single reconstruction step. Moreover, we demonstrate the possibility of obtaining well-focused biological cells flowing into a tilted microfluidic channel.

© 2013 Optical Society of America

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W. Ortyn, D. Perry, and V. Venkatachalam, Cytom. A 71A, 215 (2007).
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J. Wu, G. Zheng, and L. M. Lee, Lab Chip 12, 3566 (2012).
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Y. Liao, J. Song, E. Li, Y. Luo, Y. Shen, D. Chen, Y. Cheng, Z. Xu, K. Sugioka, and K. Midorikawa, Lab Chip 12, 746 (2012).
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Yang, C.

G. Zheng, S. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, Proc. Natl. Acad. Sci. USA 108, 16889 (2011).
[CrossRef]

Yang, Q.

Yaqoob, Z.

X. Heng, L. Baugh, and Z. Yaqoob, Lab Chip 6, 1274 (2006).
[CrossRef]

Zhao, Y.

Zheng, G.

J. Wu, G. Zheng, and L. M. Lee, Lab Chip 12, 3566 (2012).
[CrossRef]

G. Zheng, S. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, Proc. Natl. Acad. Sci. USA 108, 16889 (2011).
[CrossRef]

Appl. Opt. (6)

Cytom. A (1)

W. Ortyn, D. Perry, and V. Venkatachalam, Cytom. A 71A, 215 (2007).
[CrossRef]

J. Disp. Technol. (1)

M. Paturzo and A. Finizio, J. Disp. Technol. 7, 24 (2011).
[CrossRef]

Lab Chip (5)

P. Memmolo, R. Puglisi, D. Balduzzi, A. Galli, and P. Ferraro, Lab Chip 12, 3073 (2012).
[CrossRef]

Y. Liao, J. Song, E. Li, Y. Luo, Y. Shen, D. Chen, Y. Cheng, Z. Xu, K. Sugioka, and K. Midorikawa, Lab Chip 12, 746 (2012).
[CrossRef]

X. Heng, L. Baugh, and Z. Yaqoob, Lab Chip 6, 1274 (2006).
[CrossRef]

A. Greenbaum, U. Sikora, and A. Ozcan, Lab Chip 12, 1242 (2012).
[CrossRef]

J. Wu, G. Zheng, and L. M. Lee, Lab Chip 12, 3566 (2012).
[CrossRef]

Opt. Express (4)

Opt. Lett. (5)

Proc. Natl. Acad. Sci. USA (1)

G. Zheng, S. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, Proc. Natl. Acad. Sci. USA 108, 16889 (2011).
[CrossRef]

Supplementary Material (1)

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