Abstract

The streak camera is one of the fastest photodetection systems, while its capability of multiplexing is particularly attractive to many applications requiring parallel data acquisition. The degree of multiplexing in a streak camera is limited by the crosstalk between input channels. We developed a technique that introducing a fixed time delay between adjacent fiber channels in a customized two-dimensional to one-dimensional fiber array to significantly reduce crosstalk both at the sample plane and at the input of a streak camera. A prototype system has been developed that supports 100 input channels, and its performance in fluorescence microscopy is demonstrated.

© 2012 Optical Society of America

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References

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  1. A. J. Campillo and S. L. Shapiro, IEEE J. Quantum Electron. 19, 585 (1983).
    [CrossRef]
  2. M. Nisoli and G. Sansone, Prog. Quantum Electron. 33, 17 (2009).
    [CrossRef]
  3. J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
    [CrossRef]
  4. C. Biskup, T. Zimmer, and K. Benndorf, Nat. Biotech. 22, 220 (2004).
    [CrossRef]
  5. A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
    [CrossRef]
  6. R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
    [CrossRef]
  7. R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
    [CrossRef]
  8. J. Qu, L. Liu, D. Chen, Z. Lin, G. Xu, B. Guo, and H. Niu, Opt. Lett. 31, 368 (2006).
    [CrossRef]
  9. I. Bugiel, K. König, and H. Wabnitz, Lasers Life Sci. 3, 47 (1989).
  10. X. F. Wang, T. Uchida, and S. Minami, Appl. Spectrosc. 43, 840 (1989).
    [CrossRef]
  11. Y. Fu and J. R. Lakowicz, Anal. Chem. 78, 6238 (2006).
    [CrossRef]
  12. Y. Chen and A. Periasamy, Microsc. Res. Tech. 63, 72 (2004).
    [CrossRef]
  13. T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
    [CrossRef]
  14. Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
    [CrossRef]
  15. M. Clampin and F. Paresce, Rev. Sci. Instrum. 60, 1092 (1989).
    [CrossRef]
  16. Y. Yuan, T. Papaioannou, and Q. Fang, Opt. Lett. 33, 791 (2008).
    [CrossRef]
  17. R. W. K. Leung, S. A. Yeh, and Q. Fang, Biomed. Opt. Express 2, 2517 (2011).
    [CrossRef]
  18. Y. Sakai and S. HirayamaJ. Lumin. 39, 145 (1988).
    [CrossRef]
  19. Y. Sun, R. N. Day, and A. Periasamy, Nat. Protoc. 6, 1324 (2011).
    [CrossRef]
  20. J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
    [CrossRef]

2011

R. W. K. Leung, S. A. Yeh, and Q. Fang, Biomed. Opt. Express 2, 2517 (2011).
[CrossRef]

Y. Sun, R. N. Day, and A. Periasamy, Nat. Protoc. 6, 1324 (2011).
[CrossRef]

2010

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

2009

M. Nisoli and G. Sansone, Prog. Quantum Electron. 33, 17 (2009).
[CrossRef]

2008

2007

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

2006

2004

C. Biskup, T. Zimmer, and K. Benndorf, Nat. Biotech. 22, 220 (2004).
[CrossRef]

Y. Chen and A. Periasamy, Microsc. Res. Tech. 63, 72 (2004).
[CrossRef]

2003

R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
[CrossRef]

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

1999

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

1997

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

1991

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

1989

I. Bugiel, K. König, and H. Wabnitz, Lasers Life Sci. 3, 47 (1989).

X. F. Wang, T. Uchida, and S. Minami, Appl. Spectrosc. 43, 840 (1989).
[CrossRef]

M. Clampin and F. Paresce, Rev. Sci. Instrum. 60, 1092 (1989).
[CrossRef]

1988

Y. Sakai and S. HirayamaJ. Lumin. 39, 145 (1988).
[CrossRef]

1983

A. J. Campillo and S. L. Shapiro, IEEE J. Quantum Electron. 19, 585 (1983).
[CrossRef]

Benndorf, K.

C. Biskup, T. Zimmer, and K. Benndorf, Nat. Biotech. 22, 220 (2004).
[CrossRef]

Biskup, C.

C. Biskup, T. Zimmer, and K. Benndorf, Nat. Biotech. 22, 220 (2004).
[CrossRef]

Bugiel, I.

I. Bugiel, K. König, and H. Wabnitz, Lasers Life Sci. 3, 47 (1989).

Campillo, A. J.

A. J. Campillo and S. L. Shapiro, IEEE J. Quantum Electron. 19, 585 (1983).
[CrossRef]

Carrero, J.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Centonze, V. E.

R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
[CrossRef]

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

Chen, D.

Chen, Y.

Y. Chen and A. Periasamy, Microsc. Res. Tech. 63, 72 (2004).
[CrossRef]

Clampin, M.

M. Clampin and F. Paresce, Rev. Sci. Instrum. 60, 1092 (1989).
[CrossRef]

Day, R. N.

Y. Sun, R. N. Day, and A. Periasamy, Nat. Protoc. 6, 1324 (2011).
[CrossRef]

Elder, A. D.

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

Fang, Q.

Frank, J. H.

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

French, T.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Fu, Y.

Y. Fu and J. R. Lakowicz, Anal. Chem. 78, 6238 (2006).
[CrossRef]

Gratton, E.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Guo, B.

Hansroul, M.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

Hayakawa, T.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Herman, B.

R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
[CrossRef]

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

Hirayama, S.

Y. Sakai and S. HirayamaJ. Lumin. 39, 145 (1988).
[CrossRef]

Jeyasekharan, A. D.

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

Kagiwada, S.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Kaminski, C. F.

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

König, K.

I. Bugiel, K. König, and H. Wabnitz, Lasers Life Sci. 3, 47 (1989).

Krishnan, R. V.

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
[CrossRef]

Kusumi, A.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Lakowicz, J. R.

Y. Fu and J. R. Lakowicz, Anal. Chem. 78, 6238 (2006).
[CrossRef]

Leung, R. W. K.

Li, H.

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

Lin, Z.

Liu, L.

Masuda, A.

R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
[CrossRef]

Minami, S.

Mizeret, J.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

Murata, M.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Nisoli, M.

M. Nisoli and G. Sansone, Prog. Quantum Electron. 33, 17 (2009).
[CrossRef]

Niu, H.

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

J. Qu, L. Liu, D. Chen, Z. Lin, G. Xu, B. Guo, and H. Niu, Opt. Lett. 31, 368 (2006).
[CrossRef]

Ohnishi, S.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Papaioannou, T.

Paresce, F.

M. Clampin and F. Paresce, Rev. Sci. Instrum. 60, 1092 (1989).
[CrossRef]

Periasamy, A.

Y. Sun, R. N. Day, and A. Periasamy, Nat. Protoc. 6, 1324 (2011).
[CrossRef]

Y. Chen and A. Periasamy, Microsc. Res. Tech. 63, 72 (2004).
[CrossRef]

Qi, J.

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

Qu, J.

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

J. Qu, L. Liu, D. Chen, Z. Lin, G. Xu, B. Guo, and H. Niu, Opt. Lett. 31, 368 (2006).
[CrossRef]

Saitoh, H.

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

Sakai, Y.

Y. Sakai and S. HirayamaJ. Lumin. 39, 145 (1988).
[CrossRef]

Sako, Y.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Sampaio, T. C.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Sansone, G.

M. Nisoli and G. Sansone, Prog. Quantum Electron. 33, 17 (2009).
[CrossRef]

Shao, Y.

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

Shapiro, S. L.

A. J. Campillo and S. L. Shapiro, IEEE J. Quantum Electron. 19, 585 (1983).
[CrossRef]

So, P. T. C.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Stepinac, T.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

Studzinski, A.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

Sun, Y.

Y. Sun, R. N. Day, and A. Periasamy, Nat. Protoc. 6, 1324 (2011).
[CrossRef]

Swartling, J.

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

Terada, H.

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

Tsuji, A.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Uchida, T.

van den Bergh, H.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

Venkitaraman, A. R.

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

Voss, E. W.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Wabnitz, H.

I. Bugiel, K. König, and H. Wabnitz, Lasers Life Sci. 3, 47 (1989).

Wagnieres, G.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

Wang, X. F.

Weaver, D. J.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

Xu, G.

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

J. Qu, L. Liu, D. Chen, Z. Lin, G. Xu, B. Guo, and H. Niu, Opt. Lett. 31, 368 (2006).
[CrossRef]

Yeh, S. A.

Yoshizawa, A. C.

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Yuan, Y.

Zimmer, T.

C. Biskup, T. Zimmer, and K. Benndorf, Nat. Biotech. 22, 220 (2004).
[CrossRef]

Anal. Chem.

Y. Fu and J. R. Lakowicz, Anal. Chem. 78, 6238 (2006).
[CrossRef]

Appl. Phys. B

Y. Shao, J. Qu, H. Li, J. Qi, G. Xu, and H. Niu, Appl. Phys. B 99, 633 (2010).
[CrossRef]

Appl. Spectrosc.

Biochemistry

A. Kusumi, A. Tsuji, M. Murata, Y. Sako, A. C. Yoshizawa, S. Kagiwada, T. Hayakawa, and S. Ohnishi, Biochemistry 30, 6517 (1991).
[CrossRef]

Biomed. Opt. Express

IEEE J. Quantum Electron.

A. J. Campillo and S. L. Shapiro, IEEE J. Quantum Electron. 19, 585 (1983).
[CrossRef]

J. Biomed. Opt.

R. V. Krishnan, A. Masuda, V. E. Centonze, and B. Herman, J. Biomed. Opt. 8, 362 (2003).
[CrossRef]

J. Lumin.

Y. Sakai and S. HirayamaJ. Lumin. 39, 145 (1988).
[CrossRef]

J. Microsc.

T. French, P. T. C. So, D. J. Weaver, T. C. Sampaio, E. Gratton, E. W. Voss, and J. Carrero, J. Microsc. 185, 339 (1997).
[CrossRef]

J. H. Frank, A. D. Elder, J. Swartling, A. R. Venkitaraman, A. D. Jeyasekharan, and C. F. Kaminski, J. Microsc. 227, 203 (2007).
[CrossRef]

Lasers Life Sci.

I. Bugiel, K. König, and H. Wabnitz, Lasers Life Sci. 3, 47 (1989).

Microsc. Res. Tech.

Y. Chen and A. Periasamy, Microsc. Res. Tech. 63, 72 (2004).
[CrossRef]

Nat. Biotech.

C. Biskup, T. Zimmer, and K. Benndorf, Nat. Biotech. 22, 220 (2004).
[CrossRef]

Nat. Protoc.

Y. Sun, R. N. Day, and A. Periasamy, Nat. Protoc. 6, 1324 (2011).
[CrossRef]

Opt. Lett.

Prog. Quantum Electron.

M. Nisoli and G. Sansone, Prog. Quantum Electron. 33, 17 (2009).
[CrossRef]

Rev. Sci. Instrum.

J. Mizeret, T. Stepinac, M. Hansroul, A. Studzinski, H. van den Bergh, and G. Wagnieres, Rev. Sci. Instrum. 70, 4689 (1999).
[CrossRef]

R. V. Krishnan, H. Saitoh, H. Terada, V. E. Centonze, and B. Herman, Rev. Sci. Instrum. 74, 2714 (2003).
[CrossRef]

M. Clampin and F. Paresce, Rev. Sci. Instrum. 60, 1092 (1989).
[CrossRef]

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Figures (3)

Fig. 1.
Fig. 1.

Instrument setup for multiple delay optical fiber array streak imaging.

Fig. 2.
Fig. 2.

Streak images of fiber array inputs, with corresponding intensity profiles. (a) Fiber array imaged at the sweep off mode, (b) fiber array imaged at the sweep on mode. The left and right columns of streaks are from the 1 and 2 m fibers, respectively. (c) Magnified view of spots in the sweep off mode with corresponding intensity profile, (d), (e) magnified views of the sweep off mode and the corresponding intensity profiles.

Fig. 3.
Fig. 3.

Reconstructed fluorescence intensity images of fixed Convallaria specimens imaged (a) without sweeping and (b) with sweeping. When the streak camera is not sweeping (a), the fiber delay between adjacent fibers is not present and the image is reconstructed from steady-state acquisitions such as in Fig. 2(c). When the streak camera is sweeping (b), the image is reconstructed from time-resolved acquisitions such as in Figs. 2(d)–(e).

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