Abstract

We present a fiber based multifunctional Jones matrix swept source optical coherence tomography (SS-OCT) system for Doppler and polarization imaging. Jones matrix measurement without using active components such as electro-optic modulators is realized by incident polarization multiplexing based on independent delay of two orthogonal polarization states and polarization diversity detection. In addition to polarization sensitivity, this system measures Doppler flow without extra hardware for phase stabilized SS-OCT detection. An eighth-wave plate was measured to demonstrate the polarization detection accuracy. The optic nerve head of a retina was measured in vivo. Detailed vasculature and birefringent structures were investigated simultaneously.

© 2012 Optical Society of America

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References

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2012 (1)

2011 (2)

2010 (1)

2009 (2)

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

A. Miyazawa, M. Yamanari, S. Makita, M. Miura, K. Kawana, K. Iwaya, H. Goto, and Y. Yasuno, Opt. Express 17, 17426 (2009).
[Crossref]

2008 (2)

M. Yamanari, S. Makita, and Y. Yasuno, Opt. Express 16, 5892 (2008).
[Crossref]

M. Yamanari, M. Miura, S. Makita, T. Yatagai, and Y. Yasuno, J. Biomed. Opt. 13, 014013 (2008).
[Crossref]

2006 (1)

2004 (1)

2002 (1)

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

2000 (2)

Barry, S.

Bartlett, L. A.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Baumann, B.

Bouma, B. E.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Cable, A. E.

Cense, B.

Chen, Z.

Costa, V. P.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

de Boer, J. F.

Duker, J. S.

Flammer, J.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Fujimoto, J. G.

Fukuda, S.

Fukumura, D.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Goto, H.

Hasan, Y.

Hong, Y.

Huang, D.

Itoh, M.

Iwaya, K.

Jaillon, F.

Jain, R. K.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Ju, M. J.

Kaji, Y.

Kawana, K.

Kim, K. H.

Kiuchi, T.

Krieglstein, G. K.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Lanning, R. M.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Lee, B. H.

Lee, B. L.

Li, J.

Lim, Y.

Makita, S.

Min, E. J.

Miura, M.

Miyazawa, A.

Munn, L. L.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Nelson, J. S.

Orgul, S.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Orzalesi, N.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Oshika, T.

Padera, T. P.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Park, B. H.

Pierce, M. C.

Potsaid, B.

Renard, J.-P.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Saxer, C.

Saxer, C. E.

Schuman, J. S.

Serra, L. M.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Stefansson, E.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

Stylianopoulos, T.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Tearney, G. J.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Tu, Y.

Tyrrell, J. A.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Vakoc, B. J.

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Xiang, S.

Yamanari, M.

Yasuno, Y.

Yatagai, T.

M. Yamanari, M. Miura, S. Makita, T. Yatagai, and Y. Yasuno, J. Biomed. Opt. 13, 014013 (2008).
[Crossref]

S. Makita, Y. Hong, M. Yamanari, T. Yatagai, and Y. Yasuno, Opt. Express 14, 7821 (2006).
[Crossref]

Zhao, Y.

Biomed. Opt. Express (1)

J. Biomed. Opt. (1)

M. Yamanari, M. Miura, S. Makita, T. Yatagai, and Y. Yasuno, J. Biomed. Opt. 13, 014013 (2008).
[Crossref]

Nat. Med. (1)

B. J. Vakoc, R. M. Lanning, J. A. Tyrrell, T. P. Padera, L. A. Bartlett, T. Stylianopoulos, L. L. Munn, G. J. Tearney, D. Fukumura, R. K. Jain, and B. E. Bouma, Nat. Med. 15, 1219 (2009).
[Crossref]

Opt. Express (6)

Opt. Lett. (3)

Prog. Retin. Eye Res. (1)

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieglstein, L. M. Serra, J.-P. Renard, and E. Stefansson, Prog. Retin. Eye Res. 21, 359 (2002).
[Crossref]

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Figures (3)

Fig. 1.
Fig. 1.

Scheme of the MF-OCT. A/D, Analog-to-digital converter; BS, beam splitter; FC, fiber collimator; PBS, polarization beam splitter; PC, polarization controller; P, polarizer.

Fig. 2.
Fig. 2.

Measured phase retardation, and relative orientation of an eighth-wave plate.

Fig. 3.
Fig. 3.

En face images of (a) intensity, (b) phase retardation, and (c) power of Doppler shift, of an optic nerve head. (d) Magnified image of the square area in (c). (e) Intensity and (f) phase retardation cross section taken from the dashed line in (a).

Equations (6)

Equations on this page are rendered with MathJax. Learn more.

E0=[10]+[0eikζ]=[1eikζ],
Jmeasured=JoutJsampleJin[J11J12J21J22].
{Esamp=ESJmeasuredE0eikzsampEref=ER[11]eikzref,
{Esamp,h=ES(J11+J12eikζ)eikzsampEref,h=EReikzref.
I˜h(ΔZ)J11·δ(zΔz)+J12·δ(z(Δz+ζ)).
I˜v(ΔZ)J21·δ(zΔz)+J22·δ(z(Δz+ζ)).

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