Abstract

Multidiameter single fiber reflectance (MDSFR) spectroscopy is a method that allows the quantification of μs and the phase-function-dependent parameter γ of a turbid medium by utilizing multiple fibers with different diameters. We have previously introduced the theory behind MDSFR and its limitations, and here we present an experimental validation of this method based on phantoms containing a fractal distribution of polystyrene spheres both in the absence and presence of the absorber Evans Blue.

© 2012 Optical Society of America

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References

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2011

2009

S. Kanick, D. Robinson, H. Sterenborg, and A. Amelink, Phys. Med. Biol. 54, 6991 (2009).
[CrossRef]

2008

1999

1996

B. Gélébart, E. Tinet, J. Tualle, and S. Avrillier, Pure Appl. Opt. 5, 377 (1996).
[CrossRef]

Amelink, A.

Avrillier, S.

B. Gélébart, E. Tinet, J. Tualle, and S. Avrillier, Pure Appl. Opt. 5, 377 (1996).
[CrossRef]

Bevilacqua, F.

Depeursinge, C.

Foschum, F.

Gamm, U.

Gélébart, B.

B. Gélébart, E. Tinet, J. Tualle, and S. Avrillier, Pure Appl. Opt. 5, 377 (1996).
[CrossRef]

Kanick, S.

Kienle, A.

Michels, R.

Robinson, D.

Schouten, M.

Sterenborg, H.

Tinet, E.

B. Gélébart, E. Tinet, J. Tualle, and S. Avrillier, Pure Appl. Opt. 5, 377 (1996).
[CrossRef]

Tualle, J.

B. Gélébart, E. Tinet, J. Tualle, and S. Avrillier, Pure Appl. Opt. 5, 377 (1996).
[CrossRef]

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Figures (3)

Fig. 1.
Fig. 1.

Calculated Mie PF at 400 nm (solid red) and 800 nm (solid blue) of the phantom containing a fractal distribution of 10 sizes of polystyrene spheres, and best-fit MHG PFs (dashed lines).

Fig. 2.
Fig. 2.

Results of the MDSFR analysis: (a) SFR spectra for 5 fiber diameters (red) and MDSFR-fitted reflectance (black). (b) Real μs (black) and estimated μs from experimental data (blue) and simulated data (green dots). (c) real γ (black) and estimated γ from experimental data (green) and simulated data (light blue dots).

Fig. 3.
Fig. 3.

Results of the MDSFR analysis after adding Evans Blue as absorber. (a) SFR spectrum for dfib=0.8mm (red), fitted SFR spectrum (black), and calculated RSF0 spectrum. (b) Real μs (black) and estimated μs from experimental data (blue). (c) Real γ (black) and estimated γ from experimental data (green).

Equations (2)

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RSF0=ηlimit(1+0.63γ2e2.31γ2μsdfib)×[(μsdfib)0.57γ2.31γ2+(μsdfib)0.57γ].
RSF0=IILsim((IphantomIwater)(IILcalIwater)).

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