Abstract

We present a novel (to our knowledge) approach for measurement of the three-dimensional point spread function (PSF) of optical coherence tomography (OCT) systems using a nanoparticle-embedded phantom (NEP), toward development of standardized test methods for biophotonic imaging. The NEP comprises highly reflective plasmonic nanoparticles, homogeneously distributed in a transparent silicone matrix. OCT image volumes were analyzed to characterize PSFs in axial and lateral directions at a variety of locations in the NEP. Results indicate submicrometer agreement with conventional approaches to measure dimensions of the PSF. The NEP offers a robust approach for validating and comparing imaging performance of OCT devices.

© 2010 Optical Society of America

Full Article  |  PDF Article
Related Articles
Concentration dependence of gold nanoshells on the enhancement of optical coherence tomography images: a quantitative study

James Chen Yong Kah, Tzu Hao Chow, Beng Koon Ng, Sirajudeen Gulam Razul, Malini Olivo, and Colin James Richard Sheppard
Appl. Opt. 48(10) D96-D108 (2009)

Spatially deconvolved optical coherence tomography

Peter D. Woolliams, Robert A. Ferguson, Christian Hart, Alex Grimwood, and Peter H. Tomlins
Appl. Opt. 49(11) 2014-2021 (2010)

Cross-validation of interferometric synthetic aperture microscopy and optical coherence tomography

Tyler S. Ralston, Steven G. Adie, Daniel L. Marks, Stephen A. Boppart, and P. Scott Carney
Opt. Lett. 35(10) 1683-1685 (2010)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription