Abstract

An acousto-optic imaging technique suitable for the local and quantitative determination of subsurface optical properties in turbid media is presented. Acousto-optic signals elicited by ultrasound pulses at two different peak pressures in turbid media are detected by using photorefractive-crystal-based interferometry. The ratio of the measured signals, once calibrated for a particular set of pressure pulses, is found to give a direct measure of the reduced scattering coefficient of the interaction region between the light and sound. Measurements of the reduced scattering coefficient of inclusions buried in diffuse tissue phantoms are demonstrated.

© 2009 Optical Society of America

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References

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2008 (2)

2007 (2)

2005 (2)

2004 (3)

2000 (1)

1999 (1)

1995 (1)

1993 (1)

F. A. Marks, H. W. Tomlinson, and G. W. Brooksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

1989 (1)

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 1989/000278 (Dec. 1, 1989).

Atlan, M.

Blonigen, F. J.

Blouin, A.

Boccara, A. C.

Brooksby, G. W.

F. A. Marks, H. W. Tomlinson, and G. W. Brooksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

DiMarzio, C. A.

Dolfi, D.

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 1989/000278 (Dec. 1, 1989).

Forget, B. C.

Hemmer, P.

Jacques, S. L.

Kim, C.

Kothapalli, S. R.

Lebec, M.

Leveqe-Fort, S.

Li, Y.

Maguluri, G.

Manneville, S.

Marks, F. A.

F. A. Marks, H. W. Tomlinson, and G. W. Brooksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

Micheron, F.

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 1989/000278 (Dec. 1, 1989).

Monchalin, J. P.

Murray, T. W.

Nieva, A.

Qing, D.-K.

Ramaz, F.

Rousseau, G.

Roy, R. A.

Saint-Jalmes, H.

Sakadzic, S.

Sui, L.

Tomlinson, H. W.

F. A. Marks, H. W. Tomlinson, and G. W. Brooksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

Wang, L. V.

Xu, X.

Yao, G.

Zhang, H.

Zhao, X.

Appl. Opt. (2)

Opt. Express (3)

Opt. Lett. (6)

Phys. Rev. E (1)

S. Sakadzic and L. V. Wang, Phys. Rev. E 72, 033620 (2005).
[CrossRef]

Proc. SPIE (1)

F. A. Marks, H. W. Tomlinson, and G. W. Brooksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

Other (1)

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 1989/000278 (Dec. 1, 1989).

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Figures (4)

Fig. 1
Fig. 1

Experimental setup used for pressure contrast AOI.

Fig. 2
Fig. 2

(a) Measured AOS strength as a function of applied focal pressure in a homogeneous phantom ( μ s = 7 cm 1 ) . The inset shows the AOS detected when driving the sample with ultrasound pulses with focal pressures 0.3 and 1.5 MPa. (b) PCS at the ultrasound focus as a function of reduced scattering coefficient.

Fig. 3
Fig. 3

PCS at the ultrasound focus as a function of phantom position, revealing the presence and diffusivity of embedded scattering inclusions.

Fig. 4
Fig. 4

A pressure contrast image of a scattering inclusion of μ s = 10 cm 1 embedded in a μ s = 7 cm 1 phantom. The color bar corresponds to the measured mean PCS.

Equations (2)

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I s ( t ) = χ ( η ( z , t ) ) ( ν ( α , γ ) ) { 1 n j = 1 n [ 1 J 0 ( | Φ j | ) ] } ,
PCS = I s P f 2 I s P f 1 = j = 1 n [ 1 J 0 ( | β P j f 2 | ) ] j = 1 n [ 1 J 0 ( | β P j f 1 | ) ] .

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