Abstract

The spectroscopic content within optical coherence tomography (OCT) data can provide a wealth of information. Spectroscopic OCT methods are frequently limited by time-frequency trade-offs that limit high spectral and spatial resolution simultaneously. We present spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope. Restricting the spatial extent of the signal by using high-numerical-aperture optics makes high-resolution spectroscopic information accessible, facilitated with spectral-domain detection. Simultaneous acquisition of multiphoton microscopy images is used to validate tissue structure and localization of nuclei within individual cells.

© 2006 Optical Society of America

Full Article  |  PDF Article
Related Articles
Wavelength-dependent scattering in spectroscopic optical coherence tomography

Chenyang Xu, P. Scott Carney, and Stephen A. Boppart
Opt. Express 13(14) 5450-5462 (2005)

High speed optical coherence microscopy with autofocus adjustment and a miniaturized endoscopic imaging probe

Aaron D. Aguirre, Juergen Sawinski, Shu-Wei Huang, Chao Zhou, Winfried Denk, and James G. Fujimoto
Opt. Express 18(5) 4222-4239 (2010)

Scatterer size-based analysis of optical coherence tomography images using spectral estimation techniques

Andreas Kartakoullis, Evgenia Bousi, and Costas Pitris
Opt. Express 18(9) 9181-9191 (2010)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription