Abstract

In this paper the optimal lighting for oral cavity detection is proposed. The illuminants consist of several LEDs with different intensity ratios and peak wavelengths, which can enhance the color difference between normal and abnormal regions in the oral cavity. An algorithm combined with multi-spectral imaging (MSI) and color reproduction technique is applied to find the best enhancement of this difference. The colored LEDs of the optimal lighting, the Color Rendering Index (CRI) of the illuminants, and comparison with traditional illuminants are discussed. The calculations show that color enhancement ability in the oral cavity is not entirely a function of the higher CRI of some illuminants, as the narrowband illuminants (LEDs) produce an image with greater contrast than the broadband spectra and higher CRI of traditional illuminants in the reddish oral environment. Accordingly, an illuminant with specific intensity ratio of red, green, and blue LEDs is proposed, which has optimal color enhancement for oral cavity detection. Compared with the fluorescent lighting commonly in the use now, the color difference between normal and inflamed tissues can be improved from 21.5732 to 30.5532, a 42% increase, thus making medical diagnosis more efficient, so helping patients receive early treatment.

© 2012 OSA

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    [CrossRef] [PubMed]
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2010 (4)

2009 (2)

2008 (1)

M. Rahman, P. Chaturvedi, A. M. Gillenwater, and R. Richards-Kortum, “Low-cost, multimodal, portable screening system for early detection of oral cancer,” J. Biomed. Opt. 13(3), 030502 (2008).
[CrossRef] [PubMed]

2007 (1)

K. Hashimoto, T. Yano, M. Shimizu, and Y. Nayatani, “New method for specifying color-rendering properties of light sources based on feeling of contrast,” Color Res. Appl. 32(5), 361–371 (2007).
[CrossRef]

2006 (1)

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

2005 (1)

Y. Ohno, “Spectral design considerations for white LED color rendering,” Opt. Eng. 44(11), 111302 (2005).
[CrossRef]

2003 (1)

J. A. Worthey, “Color rendering: Asking the question,” Color Res. Appl. 28(6), 403–412 (2003).
[CrossRef]

2002 (1)

C. J. Li, M. R. Luo, B. Rigg, and R. W. G. Hunt, “CMC 2000 chromatic adaptation transform: CMCCAT2000,” Color Res. Appl. 27(1), 49–58 (2002).
[CrossRef]

2001 (1)

M. Yamaguchi, “Medical application of a color reproduction system with a multispectral camera,” Dig. Color Imaging Biomed., 33–38 (2001)

1992 (1)

C. S. McCamy, “Correlated color temperature as an explicit function of chromaticity coordinates,” Color Res. Appl. 17(2), 142–144 (1992).
[CrossRef]

1972 (1)

Bouchard, M. B.

Burgess, S. A.

Chaturvedi, P.

M. Rahman, P. Chaturvedi, A. M. Gillenwater, and R. Richards-Kortum, “Low-cost, multimodal, portable screening system for early detection of oral cancer,” J. Biomed. Opt. 13(3), 030502 (2008).
[CrossRef] [PubMed]

Chen, B. R.

Chen, Y. T.

Cheng, F. H.

Chiang, C. P.

Corell, D.

Dam-Hansen, C.

Davis, W.

W. Davis and Y. Ohno, “Color quality scale,” Opt. Eng. 49(3), 033602 (2010).
[CrossRef]

Friis, D.

Gilhuly, T.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Gillenwater, A. M.

M. Rahman, P. Chaturvedi, A. M. Gillenwater, and R. Richards-Kortum, “Low-cost, multimodal, portable screening system for early detection of oral cancer,” J. Biomed. Opt. 13(3), 030502 (2008).
[CrossRef] [PubMed]

Hashimoto, K.

K. Hashimoto, T. Yano, M. Shimizu, and Y. Nayatani, “New method for specifying color-rendering properties of light sources based on feeling of contrast,” Color Res. Appl. 32(5), 361–371 (2007).
[CrossRef]

Hillman, E. M. C.

Hunt, R. W. G.

C. J. Li, M. R. Luo, B. Rigg, and R. W. G. Hunt, “CMC 2000 chromatic adaptation transform: CMCCAT2000,” Color Res. Appl. 27(1), 49–58 (2002).
[CrossRef]

Kuo, C. C.

Lane, P. M.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Li, C. J.

C. J. Li, M. R. Luo, B. Rigg, and R. W. G. Hunt, “CMC 2000 chromatic adaptation transform: CMCCAT2000,” Color Res. Appl. 27(1), 49–58 (2002).
[CrossRef]

Lin, J. T.

Luo, M. R.

C. J. Li, M. R. Luo, B. Rigg, and R. W. G. Hunt, “CMC 2000 chromatic adaptation transform: CMCCAT2000,” Color Res. Appl. 27(1), 49–58 (2002).
[CrossRef]

MacAulay, C. E.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

McCamy, C. S.

C. S. McCamy, “Correlated color temperature as an explicit function of chromaticity coordinates,” Color Res. Appl. 17(2), 142–144 (1992).
[CrossRef]

Nayatani, Y.

K. Hashimoto, T. Yano, M. Shimizu, and Y. Nayatani, “New method for specifying color-rendering properties of light sources based on feeling of contrast,” Color Res. Appl. 32(5), 361–371 (2007).
[CrossRef]

Ng, S.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Ohno, Y.

W. Davis and Y. Ohno, “Color quality scale,” Opt. Eng. 49(3), 033602 (2010).
[CrossRef]

Y. Ohno, “Spectral design considerations for white LED color rendering,” Opt. Eng. 44(11), 111302 (2005).
[CrossRef]

Ou, H.

Petersen, P. M.

Poh, C. F.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Rahman, M.

M. Rahman, P. Chaturvedi, A. M. Gillenwater, and R. Richards-Kortum, “Low-cost, multimodal, portable screening system for early detection of oral cancer,” J. Biomed. Opt. 13(3), 030502 (2008).
[CrossRef] [PubMed]

Richards-Kortum, R.

M. Rahman, P. Chaturvedi, A. M. Gillenwater, and R. Richards-Kortum, “Low-cost, multimodal, portable screening system for early detection of oral cancer,” J. Biomed. Opt. 13(3), 030502 (2008).
[CrossRef] [PubMed]

Rigg, B.

C. J. Li, M. R. Luo, B. Rigg, and R. W. G. Hunt, “CMC 2000 chromatic adaptation transform: CMCCAT2000,” Color Res. Appl. 27(1), 49–58 (2002).
[CrossRef]

Rosin, M. P.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Shimizu, M.

K. Hashimoto, T. Yano, M. Shimizu, and Y. Nayatani, “New method for specifying color-rendering properties of light sources based on feeling of contrast,” Color Res. Appl. 32(5), 361–371 (2007).
[CrossRef]

Shur, M.

Sun, W. S.

Thornton, W. A.

Tsuei, C. H.

Vaicekauskas, R.

Wang, H. C.

Whitehead, P.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Williams, P. M.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Worthey, J. A.

J. A. Worthey, “Color rendering: Asking the question,” Color Res. Appl. 28(6), 403–412 (2003).
[CrossRef]

Yamaguchi, M.

M. Yamaguchi, “Medical application of a color reproduction system with a multispectral camera,” Dig. Color Imaging Biomed., 33–38 (2001)

Yano, T.

K. Hashimoto, T. Yano, M. Shimizu, and Y. Nayatani, “New method for specifying color-rendering properties of light sources based on feeling of contrast,” Color Res. Appl. 32(5), 361–371 (2007).
[CrossRef]

Zeng, H.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Zhang, L.

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

Žukauskas, A.

Color Res. Appl. (4)

K. Hashimoto, T. Yano, M. Shimizu, and Y. Nayatani, “New method for specifying color-rendering properties of light sources based on feeling of contrast,” Color Res. Appl. 32(5), 361–371 (2007).
[CrossRef]

J. A. Worthey, “Color rendering: Asking the question,” Color Res. Appl. 28(6), 403–412 (2003).
[CrossRef]

C. J. Li, M. R. Luo, B. Rigg, and R. W. G. Hunt, “CMC 2000 chromatic adaptation transform: CMCCAT2000,” Color Res. Appl. 27(1), 49–58 (2002).
[CrossRef]

C. S. McCamy, “Correlated color temperature as an explicit function of chromaticity coordinates,” Color Res. Appl. 17(2), 142–144 (1992).
[CrossRef]

Dig. Color Imaging Biomed. (1)

M. Yamaguchi, “Medical application of a color reproduction system with a multispectral camera,” Dig. Color Imaging Biomed., 33–38 (2001)

J. Biomed. Opt. (2)

M. Rahman, P. Chaturvedi, A. M. Gillenwater, and R. Richards-Kortum, “Low-cost, multimodal, portable screening system for early detection of oral cancer,” J. Biomed. Opt. 13(3), 030502 (2008).
[CrossRef] [PubMed]

P. M. Lane, T. Gilhuly, P. Whitehead, H. Zeng, C. F. Poh, S. Ng, P. M. Williams, L. Zhang, M. P. Rosin, and C. E. MacAulay, “Simple device for the direct visualization of oral-cavity tissue fluorescence,” J. Biomed. Opt. 11(2), 024006 (2006).
[CrossRef] [PubMed]

J. Opt. Soc. Am. (1)

Opt. Eng. (2)

W. Davis and Y. Ohno, “Color quality scale,” Opt. Eng. 49(3), 033602 (2010).
[CrossRef]

Y. Ohno, “Spectral design considerations for white LED color rendering,” Opt. Eng. 44(11), 111302 (2005).
[CrossRef]

Opt. Express (5)

Other (9)

J. von Kries, Chromatic Adaptation, (Festschrift der Albrecht-Ludwigs-Universität 1902). Translation from D.L. MacAdam, Colorimetry-Fundamentals (SPIE Milestone Series MS 77 1993).

M. D. Fairchild, Color Appearance Models (John Wiley & Sons, 2005) p. 114.

http://msdn.microsoft.com/zh-tw/express/aa718373 .

CIE 17.4–1987, “International lighting vocabulary,” No.845–02–59 (1987).

CIE 13.3–1995, “Method of measuring and specifying colour rendering properties of light sources,” (1995).

M. Anderson, R. Motta, S. Chandrasekar, and M. Stokes, “Proposal for a standard default color space for the internet: sRGB,” IS&T/SID 4th Color Imaging Conference Proc. 238 (1996), also see http://www.w3.org/Graphics/Color/sRGB.html

P. Green and L. MacDonald, Colour Engineering: Achieving Device Independent Colour (Wiley, 2002).

E. Svistun, U. Utzinger, R. Jacob, R. K. Rebecca, A. El-Naggar, and A. Gillenwater, “Optimal visual perception and detection of oral cavity neoplasia reflectance and fluorescence,” Biomedical Topical Meeting TuA3 (2002).

D. Roblyer, C. Kurachi, A. El-Naggar, M. D. Williams, A. M. Gillenwater and R. Richards-Kortum, “Multispectral and hyperspectral in vivo imaging of the oral cavity for neoplastic tissue detection,” Biomedical Optics BTuD1 (2008).

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