Abstract

We evaluate the ultimate transverse spatial resolution that can be expected in Diffuse Optical Tomography, in the configuration of projection imaging. We show how such a performance can be approached using time-resolved measurements and reasonable assumptions, in the context of a linearized diffusion model.

© 2009 Optical Society of America

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  1. F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
    [CrossRef]
  2. J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
    [CrossRef]
  3. T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).
  4. S. Takatani and J. Ling, “Optical oximetry sensors for whole blood and tissue,” IEEE Eng. Med. Biol. Mag. 13(3), 347–357 (1994).
    [CrossRef]
  5. R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
    [CrossRef]
  6. E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
    [CrossRef]
  7. A. Kienle and T. Glanzmann, “In vivo determination of the optical properties of muscle with time-resolved reflectance using a layered model,” Phys. Med. Biol. 44(11), 2689–2702 (1999).
    [CrossRef]
  8. R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
    [CrossRef]
  9. G. Yu, T. Durduran, and G. Lech, C. Zhou, B. Chance, E. R. Mohler 3rd, and A. G. Yodh, “Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies,” J. Biomed. Opt. 10(2), 024027 (2005).
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    [CrossRef]
  11. A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
    [CrossRef]
  12. D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
    [CrossRef]
  13. M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
    [CrossRef]
  14. D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159
  15. A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
    [CrossRef]
  16. A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
    [CrossRef]
  17. S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).
  18. B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
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    [CrossRef]
  20. D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
    [CrossRef]
  21. P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
    [CrossRef]
  22. A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
    [CrossRef]
  23. P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
    [CrossRef]
  24. R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
    [CrossRef]
  25. M. S. Patterson, B. Chance, and B. C. Wilson, “Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties,” Appl. Opt. 28(12), 2331–2336 (1989).
    [CrossRef]
  26. A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
    [CrossRef]
  27. S. R. Arridge and J. C. Hebden, “Optical imaging in medicine: II. Modelling and reconstruction,” Phys. Med. Biol. 42(5), 841–853 (1997).
    [CrossRef]
  28. V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
    [CrossRef]
  29. M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
    [CrossRef]
  30. A. Khireddine, K. Benmahammed, and W. Puech, “Digital image restoration by Wiener filter in 2D case,” Adv. Eng. Software 38(7), 513–516 (2007).
    [CrossRef]
  31. H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
    [CrossRef]
  32. V. Chernomordik, R. Nossal, and A. H. Gandjbakhche, “Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments,” Med. Phys. 23(11), 1857–1861 (1996).
    [CrossRef]
  33. V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
    [CrossRef]
  34. S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
    [CrossRef]
  35. E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
    [CrossRef]

2008 (2)

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

2007 (2)

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

A. Khireddine, K. Benmahammed, and W. Puech, “Digital image restoration by Wiener filter in 2D case,” Adv. Eng. Software 38(7), 513–516 (2007).
[CrossRef]

2006 (3)

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
[CrossRef]

2005 (5)

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

2004 (2)

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

2003 (2)

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
[CrossRef]

2002 (2)

D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

2001 (2)

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

2000 (2)

V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
[CrossRef]

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

1999 (2)

A. Kienle and T. Glanzmann, “In vivo determination of the optical properties of muscle with time-resolved reflectance using a layered model,” Phys. Med. Biol. 44(11), 2689–2702 (1999).
[CrossRef]

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

1997 (1)

S. R. Arridge and J. C. Hebden, “Optical imaging in medicine: II. Modelling and reconstruction,” Phys. Med. Biol. 42(5), 841–853 (1997).
[CrossRef]

1996 (2)

V. Chernomordik, R. Nossal, and A. H. Gandjbakhche, “Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments,” Med. Phys. 23(11), 1857–1861 (1996).
[CrossRef]

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

1995 (3)

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
[CrossRef]

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

1994 (1)

S. Takatani and J. Ling, “Optical oximetry sensors for whole blood and tissue,” IEEE Eng. Med. Biol. Mag. 13(3), 347–357 (1994).
[CrossRef]

1989 (2)

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

M. S. Patterson, B. Chance, and B. C. Wilson, “Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties,” Appl. Opt. 28(12), 2331–2336 (1989).
[CrossRef]

1977 (1)

F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
[CrossRef]

Andersson-Engels, S.

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

Aronson, R.

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

Arpaia, F

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

Arridge, S. R.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

S. R. Arridge and J. C. Hebden, “Optical imaging in medicine: II. Modelling and reconstruction,” Phys. Med. Biol. 42(5), 841–853 (1997).
[CrossRef]

Austin, T.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

Avrillier, S.

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Barbour, R. L.

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

Barbour, S. L. S.

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

Bassi, A.

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

Benmahammed, K.

A. Khireddine, K. Benmahammed, and W. Puech, “Digital image restoration by Wiener filter in 2D case,” Adv. Eng. Software 38(7), 513–516 (2007).
[CrossRef]

Boas, D.

D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159

Boas, D. A.

D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
[CrossRef]

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Brooksby, B.

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Brukilacchio, T. J.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Carpenter, C. M.

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

Chance, B.

V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
[CrossRef]

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

M. S. Patterson, B. Chance, and B. C. Wilson, “Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties,” Appl. Opt. 28(12), 2331–2336 (1989).
[CrossRef]

Chang, J. W.

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

Chaves, T.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Cheikh, M.

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Chernomordik, V.

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

V. Chernomordik, R. Nossal, and A. H. Gandjbakhche, “Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments,” Med. Phys. 23(11), 1857–1861 (1996).
[CrossRef]

Chikoidze, E.

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

Chorlton, M. A.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Cubeddu, R.

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

Culver, J.

D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159

Danesini, G.

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

De Blasi, R. A.

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

Dehghani, H.

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

Delfino, I.

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

Delpy, D. T.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

Dunn, A.

D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159

Durduran, T.

G. Yu, T. Durduran, and G. Lech, C. Zhou, B. Chance, E. R. Mohler 3rd, and A. G. Yodh, “Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies,” J. Biomed. Opt. 10(2), 024027 (2005).

Esposito, R.

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

Ettori, D.

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Everdell, N.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

Everdell, N. L.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

Fantini, S.

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

Ferrari, M.

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

Ferraro, N.

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

Filiaci, M.

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

Franceschini, M. A.

D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
[CrossRef]

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

Gandjbakhche, A.

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

Gandjbakhche, A. H.

V. Chernomordik, R. Nossal, and A. H. Gandjbakhche, “Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments,” Med. Phys. 23(11), 1857–1861 (1996).
[CrossRef]

Gebauer, B.

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

Gibson, A.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

Gibson, A. P.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

Glanzmann, T.

A. Kienle and T. Glanzmann, “In vivo determination of the optical properties of muscle with time-resolved reflectance using a layered model,” Phys. Med. Biol. 44(11), 2689–2702 (1999).
[CrossRef]

Graber, H. L.

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

Gratton, E.

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

Graves, E. E.

E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
[CrossRef]

Grosenick, D.

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

Guo, P.

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

Hamaoka, T.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Hebden, J. C.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

S. R. Arridge and J. C. Hebden, “Optical imaging in medicine: II. Modelling and reconstruction,” Phys. Med. Biol. 42(5), 841–853 (1997).
[CrossRef]

Hielscher, A. H.

A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
[CrossRef]

Higuchi, H.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Hillman, E. M. C.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

Huppert, T. J.

D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
[CrossRef]

Iwane, H.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Jacques, S. L.

A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
[CrossRef]

Ji, L.

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

Jiang, S.

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Jiang, T.

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

Jöbsis, F. F.

F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
[CrossRef]

Joseph, D. K.

D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
[CrossRef]

Katsumura, T.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Khireddine, A.

A. Khireddine, K. Benmahammed, and W. Puech, “Digital image restoration by Wiener filter in 2D case,” Adv. Eng. Software 38(7), 513–516 (2007).
[CrossRef]

Kienle, A.

A. Kienle and T. Glanzmann, “In vivo determination of the optical properties of muscle with time-resolved reflectance using a layered model,” Phys. Med. Biol. 44(11), 2689–2702 (1999).
[CrossRef]

Kilmer, M. E.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Kogel, C.

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Konecky, S. D.

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

Koo, P. C.

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

Kopans, D. B.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Kummrow, A.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

Lanoce, V.

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

Lech, G.

G. Yu, T. Durduran, and G. Lech, C. Zhou, B. Chance, E. R. Mohler 3rd, and A. G. Yodh, “Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies,” J. Biomed. Opt. 10(2), 024027 (2005).

Lee, K.

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

Lepore, M.

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

Li, A.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Liebert, A.

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Ling, J.

S. Takatani and J. Ling, “Optical oximetry sensors for whole blood and tissue,” IEEE Eng. Med. Biol. Mag. 13(3), 347–357 (1994).
[CrossRef]

Macdonald, R.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Mancini, D. M.

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
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Markel, V.

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

McCully, K.

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

Meek, J. H.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

Miller, E. L.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Miwa, M.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Moesta, K. T.

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

Möller, M.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Moore, R. H.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Mucke, J.

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

Murase, N.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Nghiêm, H. L.

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Nishio, S.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Niu, H.

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

Nossal, R.

V. Chernomordik, R. Nossal, and A. H. Gandjbakhche, “Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments,” Med. Phys. 23(11), 1857–1861 (1996).
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Ntziachristos, V.

E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
[CrossRef]

V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
[CrossRef]

Obrig, H.

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Osada, T.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Panasyuk, G. Y.

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

Patterson, M. S.

M. S. Patterson, B. Chance, and B. C. Wilson, “Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties,” Appl. Opt. 28(12), 2331–2336 (1989).
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Paulsen, K. D.

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Pifferi, A.

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

Pogue, B. W.

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Poplack, S. P.

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Puech, W.

A. Khireddine, K. Benmahammed, and W. Puech, “Digital image restoration by Wiener filter in 2D case,” Adv. Eng. Software 38(7), 513–516 (2007).
[CrossRef]

Rinneberg, H.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Ripoll, J.

E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
[CrossRef]

Sako, T.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Schlag, P. M.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

Schmidt, F. E. W.

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

Schnall, M.

V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
[CrossRef]

Schotland, J. C.

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

Schweiger, M.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
[CrossRef]

Shimomitsu, T.

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Spinelli, L.

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

Srinivasan, S.

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Steinbrink, J.

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Stott, J.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159

Stroszczynski, C.

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

Swartling, J.

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

Takatani, S.

S. Takatani and J. Ling, “Optical oximetry sensors for whole blood and tissue,” IEEE Eng. Med. Biol. Mag. 13(3), 347–357 (1994).
[CrossRef]

Taroni, P.

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

Tinet, E.

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Tittel, F. K.

A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
[CrossRef]

Toronov, V.

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

Torricelli, A.

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

Tualle, J. M.

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Valentini, G.

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

Villringer, A.

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Wabnitz, H.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

Wang, L.

A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
[CrossRef]

Wassermann, B.

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

Weissleder, R.

E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
[CrossRef]

Wells, W. A.

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Wilson, B. C.

M. S. Patterson, B. Chance, and B. C. Wilson, “Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties,” Appl. Opt. 28(12), 2331–2336 (1989).
[CrossRef]

Wilson, J. R.

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

Wu, T.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Wyatt, J. S.

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

Yalavarthy, P. K.

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

Yodh, A. G.

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
[CrossRef]

Yu, G.

G. Yu, T. Durduran, and G. Lech, C. Zhou, B. Chance, E. R. Mohler 3rd, and A. G. Yodh, “Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies,” J. Biomed. Opt. 10(2), 024027 (2005).

Yusof, R. M.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

Zhang, Q.

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

Zhao, Q.

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

Adv. Eng. Software (1)

A. Khireddine, K. Benmahammed, and W. Puech, “Digital image restoration by Wiener filter in 2D case,” Adv. Eng. Software 38(7), 513–516 (2007).
[CrossRef]

Appl. Opt. (5)

A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, “Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of flight of photons,” Appl. Opt. 43(15), 3037–3047 (2004).
[CrossRef]

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. A. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, “Tomographic optical breast imaging guided by three-dimensional mammography,” Appl. Opt. 42(25), 5181–5190 (2003).
[CrossRef]

M. S. Patterson, B. Chance, and B. C. Wilson, “Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties,” Appl. Opt. 28(12), 2331–2336 (1989).
[CrossRef]

R. Cubeddu, A. Pifferi, P. Taroni, A. Torricelli, and G. Valentini, “Compact tissue oximeter based on dual-wavelength multichannel time-resolved reflectance,” Appl. Opt. 38(16), 3670–3680 (1999).
[CrossRef]

D. K. Joseph, T. J. Huppert, M. A. Franceschini, and D. A. Boas, “Diffuse optical tomography system to image brain activation with improved spatial resolution and validation with functional magnetic resonance imaging,” Appl. Opt. 45(31), 8142–8151 (2006).
[CrossRef]

Circulation (1)

J. R. Wilson, D. M. Mancini, K. McCully, N. Ferraro, V. Lanoce, and B. Chance, “Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure,” Circulation 80(6), 1668–1674 (1989).
[CrossRef]

IEEE Comput. Sci. Eng. (1)

R. L. Barbour, H. L. Graber, J. W. Chang, S. L. S. Barbour, P. C. Koo, and R. Aronson, “MRI-guided optical tomography: Prospects and computation for a new imaging method,” IEEE Comput. Sci. Eng. 2(4), 63–77 (1995).
[CrossRef]

IEEE Eng. Med. Biol. Mag. (1)

S. Takatani and J. Ling, “Optical oximetry sensors for whole blood and tissue,” IEEE Eng. Med. Biol. Mag. 13(3), 347–357 (1994).
[CrossRef]

J. Biomed. Opt. (2)

V. Chernomordik, A. Gandjbakhche, M. Lepore, R. Esposito, and I. Delfino, “Depth dependence of the analytical expression for the width of the point spread function (spatial resolution) in time-resolved transillumination,” J. Biomed. Opt. 6(4), 441–445 (2001).
[CrossRef]

A. Pifferi, J. Swartling, E. Chikoidze, A. Torricelli, P. Taroni, A. Bassi, S. Andersson-Engels, and R. Cubeddu, “Spectroscopic time-resolved diffuse reflectance and transmittance measurements of the female breast at different interfiber distances,” J. Biomed. Opt. 9(6), 1143–1151 (2004).
[CrossRef]

Med. Biol. Eng. Comput. (1)

R. A. De Blasi, S. Fantini, M. A. Franceschini, M. Ferrari, and E. Gratton, “Cerebral and muscle oxygen saturation measurement by frequency-domain near-infra-red spectrometer,” Med. Biol. Eng. Comput. 33(2), 228–230 (1995).
[CrossRef]

Med. Phys. (2)

V. Chernomordik, R. Nossal, and A. H. Gandjbakhche, “Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments,” Med. Phys. 23(11), 1857–1861 (1996).
[CrossRef]

E. E. Graves, J. Ripoll, R. Weissleder, and V. Ntziachristos, “A submillimeter resolution fluorescence molecular imaging system for small animal imaging,” Med. Phys. 30(5), 901–911 (2003).
[CrossRef]

Med. Sci. Sports Exerc. (1)

T. Hamaoka, H. Iwane, T. Katsumura, T. Shimomitsu, N. Murase, S. Nishio, T. Osada, T. Sako, H. Higuchi, M. Miwa, and B. Chance, “The quantitative measures of muscle oxygenation by near infrared time-resolved spectroscopy,” Med. Sci. Sports Exerc. 28(Supplement), 62 (1996).

Neuroimage (1)

A. P. Gibson, T. Austin, N. L. Everdell, M. Schweiger, S. R. Arridge, J. H. Meek, J. S. Wyatt, D. T. Delpy, and J. C. Hebden, “Three-dimensional whole-head optical tomography of passive motor evoked responses in the neonate,” Neuroimage 30(2), 521–528 (2006).
[CrossRef]

Op. Express (2)

B. Wassermann, A. Kummrow, K. T. Moesta, D. Grosenick, J. Mucke, H. Wabnitz, M. Möller, R. Macdonald, P. M. Schlag, and H. Rinneberg, “In-vivo tissue optical properties derived by linear perturbation theory for edge-corrected time-domain mammograms”, Op. Express 13, 8571–8583 (2005), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-13-21-8571
[CrossRef]

D. Boas, J. Culver, J. Stott, and A. Dunn, “Three dimensional Monte Carlo code for photon migration through complex heterogeneous media including the adult human head”, Op. Express 10, 159–170 (2002), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-10-3-159

Opt. Express (4)

H. Niu, P. Guo, L. Ji, Q. Zhao, and T. Jiang, “Improving image quality of diffuse optical tomography with a projection-error-based adaptive regularization method,” Opt. Express 16(17), 12423–12434 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-17-12423.
[CrossRef]

S. D. Konecky, G. Y. Panasyuk, K. Lee, V. Markel, A. G. Yodh, and J. C. Schotland, “Imaging complex structures with diffuse light,” Opt. Express 16(7), 5048–5060 (2008), http://www.opticsinfobase.org/abstract.cfm?URI=oe-16-7-5048.
[CrossRef]

P. K. Yalavarthy, B. W. Pogue, H. Dehghani, C. M. Carpenter, S. Jiang, and K. D. Paulsen, “Structural information within regularization matrices improves near infrared diffuse optical tomography,” Opt. Express 15(13), 8043–8058 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-13-8043.
[CrossRef]

M. A. Franceschini, V. Toronov, M. Filiaci, E. Gratton, and S. Fantini, “On-line optical imaging of the human brain with 160-ms temporal resolution,” Opt. Express 6(3), 49–57 (2000), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-6-3-49.
[CrossRef]

Opt. Lett. (1)

M. Cheikh, H. L. Nghiêm, D. Ettori, E. Tinet, S. Avrillier, and J. M. Tualle, “Time-resolved diffusing wave spectroscopy applied to dynamic heterogeneity imaging,” Opt. Lett. 31(15), 2311–2313 (2006).
[CrossRef]

Phys. Med. Biol. (8)

A. H. Hielscher, S. L. Jacques, L. Wang, and F. K. Tittel, “The influence of boundary conditions on the accuracy of diffusion theory in time-resolved reflectance spectroscopy of biological tissues,” Phys. Med. Biol. 40(11), 1957–1975 (1995).
[CrossRef]

S. R. Arridge and J. C. Hebden, “Optical imaging in medicine: II. Modelling and reconstruction,” Phys. Med. Biol. 42(5), 841–853 (1997).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, “Three-dimensional optical tomography of the premature infant brain,” Phys. Med. Biol. 47(23), 4155–4166 (2002).
[CrossRef]

D. Grosenick, K. T. Moesta, M. Möller, J. Mucke, H. Wabnitz, B. Gebauer, C. Stroszczynski, B. Wassermann, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: I. Recording and assessment of mammograms of 154 patients,” Phys. Med. Biol. 50(11), 2429–2449 (2005).
[CrossRef]

D. Grosenick, H. Wabnitz, K. T. Moesta, J. Mucke, P. M. Schlag, and H. Rinneberg, “Time-domain scanning optical mammography: II. Optical properties and tissue parameters of 87 carcinomas,” Phys. Med. Biol. 50(11), 2451–2468 (2005).
[CrossRef]

P. Taroni, A. Torricelli, L. Spinelli, A. Pifferi, F Arpaia, G. Danesini, and R. Cubeddu, “Time-resolved optical mammography between 637 and 985 nm: clinical study on the detection and identification of breast lesions,” Phys. Med. Biol. 50(11), 2469–2488 (2005).
[CrossRef]

E. M. C. Hillman, J. C. Hebden, M. Schweiger, H. Dehghani, F. E. W. Schmidt, D. T. Delpy, and S. R. Arridge, “Time resolved optical tomography of the human forearm,” Phys. Med. Biol. 46(4), 1117–1130 (2001).
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A. Kienle and T. Glanzmann, “In vivo determination of the optical properties of muscle with time-resolved reflectance using a layered model,” Phys. Med. Biol. 44(11), 2689–2702 (1999).
[CrossRef]

Proc. Natl. Acad. Sci. U.S.A. (1)

V. Ntziachristos, A. G. Yodh, M. Schnall, and B. Chance, “Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement,” Proc. Natl. Acad. Sci. U.S.A. 97(6), 2767–2772 (2000).
[CrossRef]

Science (1)

F. F. Jöbsis, “Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters,” Science 198(4323), 1264–1267 (1977).
[CrossRef]

Technol. Cancer Res. Treat. (1)

S. Srinivasan, B. W. Pogue, B. Brooksby, S. Jiang, H. Dehghani, C. Kogel, W. A. Wells, S. P. Poplack, and K. D. Paulsen, “Near-infrared characterization of breast tumors in vivo using spectrally-constrained reconstruction,” Technol. Cancer Res. Treat. 4(5), 513–526 (2005).

Other (1)

G. Yu, T. Durduran, and G. Lech, C. Zhou, B. Chance, E. R. Mohler 3rd, and A. G. Yodh, “Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies,” J. Biomed. Opt. 10(2), 024027 (2005).

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Figures (7)

Fig. 1.
Fig. 1.

Typical configuration for transmittance measurements: the source and the detector are face-to-face at both sides of the slab; the source-detector system translates over the whole plane, in order to get a projection image.

Fig. 2.
Fig. 2.

Numerical evaluation of the ratio Rd/R (blue curve), compared to the result of Eq. (14) (red curve).

Fig. 3.
Fig. 3.

Spatial resolution Rd obtained in the TR case, with µa0 =0.005mm−1 , as a function of the transit time t. A minimum is reached at topt =782ps.

Fig. 4.
Fig. 4.

(a) Optimal spatial resolution (in mm) after deconvolution in the time-resolved (TR) case as a function of the experimental parameter F. (b) Ratio of the spatial resolution in the continuous wave (CW) case over the result obtained in the TR case.

Fig. 5.
Fig. 5.

(a)- Initial target with: a single point, two discs separated from 5mm, four sets of bars with the same thickness and separation (8,7,6 and 5mm). (e)-Image (a) convoluted by the TR kernel κ, with added noise. (f)- Image (e) restored using the filter W: the spatial resolution of ~9mm allows to clearly see objects whose centers are distant from 12mm, and to distinguish objects distant from 10mm; the discs can be clearly seen, even if their separation distance is 5mm. (c,d)- Same as (e,f) in the CW case. (b)- Same as (d), but using a Gaussian approximation in the W filter.

Fig. 6.
Fig. 6.

(a)- Same as Fig. 5f. (b–f)- the kernel for the restoration was fixed to z=12mm, and used to restore images with a real position of the object that is: (b)-z=30mm; (c)-z=20mm; (d)-z=12mm; (e)- z=10mm; (f)- z=5mm;

Fig. 7.
Fig. 7.

simulations in the CW case: (a)- Same as Fig. 5d: target at z=30mm with a restoration kernel at z=30mm. (b)- target at z=30mm with a restoration kernel at z=30mm; we clearly have a resolution loss in the CW case.

Equations (19)

Equations on this page are rendered with MathJax. Learn more.

[ctD(r)μa(r)]G(r,t;rs)=δ (t)δ(rrs)
C(rd,t)lnG(rd,t)G0(rd,t)G01(rd,t;rs)0tdtd3rG0(rd,tt;r)δμa(r)G0(r,t;rs)
Cρdρs(ρd,t) d2 ρ ' d z κρdρs (ρdρ',z,t)δμa(ρ',z)
χ2(x)=fLg2+λg2
g=[L+L+λ]1L+f
W˜z,t(k)=φ [κ˜z,t(k)] and φ [X]=X*X2+λ
<b˜f2>=1N2<ijW˜ijb˜ij2>=γ<b˜2>withγ=1N2ijW˜ij2
γΔx2d2kϕ[k˜z,t(k)]2(4π2)
κ˜(k)=exp [αk2],
γΔx22π0kdkϕ[exp(αk2)]2=Δx24πα0dXXϕ2(X)Δx28παλ
γ=Signal2b2Signal2bf2=SNR2SNRf2
λ=2ln2Δx2πR2SNRf2SNR2
λ=g2SNR2
Rd1.41=πR8ln2lnλ=1.88Rlnλ
η=aEhvS
εC2ηG0Δτ
1gSNR=F Δ τ κz,t (ρ)G0(ρ,t)
FηδμaV2g
R(z,t)2.35d4Dctz(dz)

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