Abstract

Three dimensional rapid large depth range imaging of the anterior segments of the human eye by an optical frequency domain imaging system is presented. The tunable source spans from 1217 to 1356 nm with an average output power of 60 mW providing a measured axial resolution of 10 μm in air based on the coherence envelope. The effective depth range is 4 mm, defined as the distance over which the sensitivity drops by 6 dB, achieved by frequency shifting the optical signal using acousto-optic modulators. The measured maximum sensitivity is 109 dB at a sample arm power of 14.7mW and A-lines rate of 43,900 per second. Images consisting of 512 depth profiles are acquired at an acquisition rate of 85 frames per second. We demonstrate an optical frequency domain imaging system capable of mapping in vivo the entire area of the human anterior segment (13.4 × 12 × 4.2 mm) in 1.4 seconds.

© 2007 Optical Society of America

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2007 (1)

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

2006 (6)

2005 (6)

2004 (4)

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

J. W. McLaren, C. B. Nau, J. C. Erie, and W. M. Bourne, "Corneal thickness measurement by confocal microscopy, ultrasound, and scanning slit method," Am. J. Ophthalmol. 137, 1011-1020 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822-4828 (2004).
[CrossRef] [PubMed]

2003 (8)

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
[CrossRef] [PubMed]

S. H. Yun, C. Boudoux, G. J. Tearney, and B. E. Bouma, "High-speed wavelength-swept source semiconductor laser with a polygon-scanner-based wavelength filter," Opt. Lett. 28, 1981-1983 (2003).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B.E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11, 2953-2963 (2003).
[CrossRef]

S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer, "High-speed spectral-domain optical coherence tomography at 1.3μm wavelength," Opt. Express 11, 3598-3604 (2003).
[CrossRef] [PubMed]

M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183-2189 (2003).
[CrossRef] [PubMed]

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

2002 (5)

C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
[CrossRef] [PubMed]

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
[CrossRef] [PubMed]

V. Westphal, A. Rollins, S. Radhakrihnan, and J. A. Izatt, "Correction of geometric and refractive image distortions in optical coherence tomography applying Fermat’s principle," Opt. Express 10, 397-404 (2002).
[PubMed]

2001 (2)

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

2000 (1)

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

1999 (1)

G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
[CrossRef] [PubMed]

1998 (1)

G. Hausler and M. W. Linder, "Coherence Radar and Spectral Radar- new tools for dermatological diagnosis," J. Biomed. Opt. 3, 21-31 (1998).
[CrossRef]

1997 (2)

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency tunable optical source," Opt. Lett. 22, 340-342 (1997).
[CrossRef] [PubMed]

S. Roh, R. J. Noecker, and J. S. Schuman, "Evaluation of coexisting optic nerve head drusen and glaucoma with optical coherence tomography," Ophthalmology 104, 1138-1144 (1997).
[PubMed]

1996 (1)

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

1995 (1)

M. R. Hee, J. A. Izatt, and E. A. Swanson, "Optical coherence tomography of the human retina," Arch. Ophthalmol. 113, 325-332 (1995).
[CrossRef] [PubMed]

1994 (2)

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Z. Reinstein, R. H. Silverman, S. L. Trokel, and D. J. Coleman, "Corneal pachymetric topography," Ophthalmology 112, 1584-1589 (1994).

1993 (1)

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
[PubMed]

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Akiba, M.

Aliseda, D.

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

Bajraszewski, T.

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
[CrossRef] [PubMed]

Bardenstein, D.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

Baumal, C. R.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

Beekhuis, W. H.

G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
[CrossRef] [PubMed]

Belin, M. W.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Birngruber, R.

C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

Birngtuber, R.

G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
[CrossRef] [PubMed]

Boudoux, C.

Bouma, B.

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

Bouma, B. E.

Bouma, B.E.

Bourne, W. M.

J. W. McLaren, C. B. Nau, J. C. Erie, and W. M. Bourne, "Corneal thickness measurement by confocal microscopy, ultrasound, and scanning slit method," Am. J. Ophthalmol. 137, 1011-1020 (2004).
[CrossRef] [PubMed]

Cense, B.

Chan, K. P.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Chen, T.

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

Chen, T. C.

Chen, Y.

Chinn, S. R.

Choma, M. A.

Chong, C.

Cohen, E. J.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Coker, J. G.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

Coleman, D. J.

D. Z. Reinstein, R. H. Silverman, S. L. Trokel, and D. J. Coleman, "Corneal pachymetric topography," Ophthalmology 112, 1584-1589 (1994).

de Boer, J. F.

H. Lim, M. Mujat, C. Kerbage, E. C. Lee, Y. Chen, T. C. Chen, and J. F. de Boer, "High-speed imaging of human retina in vivo with swept source optical coherence tomography," Opt. Express 14, 12902-12908 (2006).
[CrossRef] [PubMed]

H. Lim, J. F. de Boer, B. H. Park, E. C. Lee, R. Yelin, and S. H. Yun, "Optical frequency domain imaging with a rapidly swept laser in the 815-870nm range," Opt. Express 14, 5937-5944 (2006).
[CrossRef] [PubMed]

E. C. W. Lee, J. F. de Boer, M. Mujat, H. Lim, and S.H. Yun, "In vivo optical frequency domain imaging of human retina and choroid," Opt. Express 14, 4403-4411 (2006).
[CrossRef] [PubMed]

B. J. Vakoc, S. H. Yun, J. F. de Boer, G. J. Tearney, and B.E. Bouma, "Phase-resolved optical frequency domain imaging," Opt. Express 13, 5483-5493 (2005).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822-4828 (2004).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B.E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11, 2953-2963 (2003).
[CrossRef]

S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer, "High-speed spectral-domain optical coherence tomography at 1.3μm wavelength," Opt. Express 11, 3598-3604 (2003).
[CrossRef] [PubMed]

Dell, I. J.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Drexler, W.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
[PubMed]

Dueker, D. K.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

Duker, J. S.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

Erie, J. C.

J. W. McLaren, C. B. Nau, J. C. Erie, and W. M. Bourne, "Corneal thickness measurement by confocal microscopy, ultrasound, and scanning slit method," Am. J. Ophthalmol. 137, 1011-1020 (2004).
[CrossRef] [PubMed]

Fercher, A. F.

R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
[CrossRef] [PubMed]

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
[CrossRef] [PubMed]

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
[PubMed]

Fercher, A.F.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Findl, O.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Fujimoto, J. G.

R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14, 3225-3237 (2006).
[CrossRef] [PubMed]

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency tunable optical source," Opt. Lett. 22, 340-342 (1997).
[CrossRef] [PubMed]

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Garcia-Layana, A.

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

Geerling, G.

G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
[CrossRef] [PubMed]

Ghanta, R. K.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

Goldsmith, J.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Haque, S.

S. Haque, T. Simpson, and L. Jones, "Corneal and Epithelial thickness in Keratoconus: A comparison of Ultrasonic Pachymetry, Obscan II, and Optical Coherence Tomography," J. Refractive Surgery 22, (2006).

Hausler, G.

G. Hausler and M. W. Linder, "Coherence Radar and Spectral Radar- new tools for dermatological diagnosis," J. Biomed. Opt. 3, 21-31 (1998).
[CrossRef]

Hee, M. R.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

M. R. Hee, J. A. Izatt, and E. A. Swanson, "Optical coherence tomography of the human retina," Arch. Ophthalmol. 113, 325-332 (1995).
[CrossRef] [PubMed]

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Hermann, B.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Hitzenberger, C. K.

R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
[CrossRef] [PubMed]

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
[PubMed]

Hoerauf, H.

G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
[CrossRef] [PubMed]

C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

Huang, D.

Y. Li, R. Shekhar, and D. Huang, "Corneal Pachymetry Mapping with high-speed Optical Coherence Tomography," Am. Acad. Ophthalmol. 113, 792-799 (2006).

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Huber, R.

Iftimia, N.

Itoh, M.

Izatt, J. A.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

M. V. Sarunic, M. A. Choma, C. Yang, and J. A. Izatt, "Instantaneous complex conjugate resolved spectral domain and swept-source OCT using 3 by 3 couplers," Opt. Express 13, 957-967 (2005).
[CrossRef] [PubMed]

M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183-2189 (2003).
[CrossRef] [PubMed]

V. Westphal, A. Rollins, S. Radhakrihnan, and J. A. Izatt, "Correction of geometric and refractive image distortions in optical coherence tomography applying Fermat’s principle," Opt. Express 10, 397-404 (2002).
[PubMed]

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

M. R. Hee, J. A. Izatt, and E. A. Swanson, "Optical coherence tomography of the human retina," Arch. Ophthalmol. 113, 325-332 (1995).
[CrossRef] [PubMed]

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

Jones, L.

S. Haque, T. Simpson, and L. Jones, "Corneal and Epithelial thickness in Keratoconus: A comparison of Ultrasonic Pachymetry, Obscan II, and Optical Coherence Tomography," J. Refractive Surgery 22, (2006).

Kamp, G.

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
[PubMed]

Kartner, F. X.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

Kaufman, S.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Kawana, K.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Keating, D.

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

Kemp, E.

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

Kerbage, C.

Ko, T. H.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Kowalczyk, A.

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
[CrossRef] [PubMed]

Lander, F.

G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
[CrossRef] [PubMed]

Laqua, H.

C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

Lee, E. C.

Lee, E. C. W.

Leitgeb, R.

R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
[CrossRef] [PubMed]

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
[CrossRef] [PubMed]

Li, Y.

Y. Li, R. Shekhar, and D. Huang, "Corneal Pachymetry Mapping with high-speed Optical Coherence Tomography," Am. Acad. Ophthalmol. 113, 792-799 (2006).

Lim, H.

Lin, C. P.

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Linder, M. W.

G. Hausler and M. W. Linder, "Coherence Radar and Spectral Radar- new tools for dermatological diagnosis," J. Biomed. Opt. 3, 21-31 (1998).
[CrossRef]

Madjarova, V. D.

Makita, S.

Maldonado, M. J.

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

May, C. A.

A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
[CrossRef] [PubMed]

McKay, N.

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

McLaren, J. W.

J. W. McLaren, C. B. Nau, J. C. Erie, and W. M. Bourne, "Corneal thickness measurement by confocal microscopy, ultrasound, and scanning slit method," Am. J. Ophthalmol. 137, 1011-1020 (2004).
[CrossRef] [PubMed]

Meisler, D.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Melles, G. R.

G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
[CrossRef] [PubMed]

Meter, W. S. V.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Miura, M.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Miyazawa, A.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Moreno-Montanes, J.

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

Morgner, U.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

Mori, H.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Morosawa, A.

Mujat, M.

Muller, M.

G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
[CrossRef] [PubMed]

Munuera, J. M.

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

Muscat, S.

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

Musch, D.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Nassif, N.

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

Nau, C. B.

J. W. McLaren, C. B. Nau, J. C. Erie, and W. M. Bourne, "Corneal thickness measurement by confocal microscopy, ultrasound, and scanning slit method," Am. J. Ophthalmol. 137, 1011-1020 (2004).
[CrossRef] [PubMed]

Neubauer, A. S.

A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
[CrossRef] [PubMed]

Noecker, R. J.

S. Roh, R. J. Noecker, and J. S. Schuman, "Evaluation of coexisting optic nerve head drusen and glaucoma with optical coherence tomography," Ophthalmology 104, 1138-1144 (1997).
[PubMed]

Oelckers, S.

G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
[CrossRef] [PubMed]

Oh, W. Y.

Oshika, T.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Park, B. H.

Parks, S.

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

Pierce, M.

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

Pierce, M. C.

Priglinger, S. G.

A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
[CrossRef] [PubMed]

Puliafito, C. A.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Puliafito, C.A.

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

Radhakrihnan, S.

Radhakrishnan, S.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

Reichel, E.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

Reinhart, W. J.

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Reinstein, D. Z.

D. Z. Reinstein, R. H. Silverman, S. L. Trokel, and D. J. Coleman, "Corneal pachymetric topography," Ophthalmology 112, 1584-1589 (1994).

Remeijer, L.

G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
[CrossRef] [PubMed]

Rietveld, F. J.

G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
[CrossRef] [PubMed]

Roh, S.

S. Roh, R. J. Noecker, and J. S. Schuman, "Evaluation of coexisting optic nerve head drusen and glaucoma with optical coherence tomography," Ophthalmology 104, 1138-1144 (1997).
[PubMed]

Rollins, A.

Rollins, A. M.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

Roth, J. E.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

Ruiz Oblitas, L.

M. J. Maldonado, L. Ruiz Oblitas, J. M. Munuera, D. Aliseda, A. Garcia-Layana, and J. Moreno-Montanes, "Optical Coherence Tomography evaluation of the corneal cap and stromal bed features after laser in situ keratomileusis for high myopia and astigmatism," Ophthalmology 107, 81-87 (2000).
[CrossRef] [PubMed]

Sakai, T.

Sarunic, M. V.

Sattmann, H.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
[PubMed]

Scholda, C.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Scholz, C.

C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

Schuman, J. S.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
[CrossRef] [PubMed]

S. Roh, R. J. Noecker, and J. S. Schuman, "Evaluation of coexisting optic nerve head drusen and glaucoma with optical coherence tomography," Ophthalmology 104, 1138-1144 (1997).
[PubMed]

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Shekhar, R.

Y. Li, R. Shekhar, and D. Huang, "Corneal Pachymetry Mapping with high-speed Optical Coherence Tomography," Am. Acad. Ophthalmol. 113, 792-799 (2006).

Silverman, R. H.

D. Z. Reinstein, R. H. Silverman, S. L. Trokel, and D. J. Coleman, "Corneal pachymetric topography," Ophthalmology 112, 1584-1589 (1994).

Simpson, T.

S. Haque, T. Simpson, and L. Jones, "Corneal and Epithelial thickness in Keratoconus: A comparison of Ultrasonic Pachymetry, Obscan II, and Optical Coherence Tomography," J. Refractive Surgery 22, (2006).

Smith, S. D.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Stur, M.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Swanson, E. A.

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency tunable optical source," Opt. Lett. 22, 340-342 (1997).
[CrossRef] [PubMed]

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

M. R. Hee, J. A. Izatt, and E. A. Swanson, "Optical coherence tomography of the human retina," Arch. Ophthalmol. 113, 325-332 (1995).
[CrossRef] [PubMed]

J. A. Izatt, M. R. Hee, E. A. Swanson, C. P. Lin, D. Huang, J. S. Schuman, C.A. Puliafito, and J. G. Fujimoto, "Micrometer-scale resolution imaging of the anterior eye in vio with optical coherence tomography," Arch. Ophthalmol. 112, 1584-1589 (1994).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
[CrossRef] [PubMed]

Tearney, G.

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

Tearney, G. J.

B. J. Vakoc, S. H. Yun, J. F. de Boer, G. J. Tearney, and B.E. Bouma, "Phase-resolved optical frequency domain imaging," Opt. Express 13, 5483-5493 (2005).
[CrossRef] [PubMed]

W. Y. Oh, S. H. Yun, G. J. Tearney, and B. E. Bouma, "115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser," Opt. Lett. 30, 3159-3161 (2005).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822-4828 (2004).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28, 2067-2069 (2003).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B.E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11, 2953-2963 (2003).
[CrossRef]

S. H. Yun, C. Boudoux, G. J. Tearney, and B. E. Bouma, "High-speed wavelength-swept source semiconductor laser with a polygon-scanner-based wavelength filter," Opt. Lett. 28, 1981-1983 (2003).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer, "High-speed spectral-domain optical coherence tomography at 1.3μm wavelength," Opt. Express 11, 3598-3604 (2003).
[CrossRef] [PubMed]

Thiel, M. J.

A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
[CrossRef] [PubMed]

Thoai Pham, D.

C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

Trokel, S. L.

D. Z. Reinstein, R. H. Silverman, S. L. Trokel, and D. J. Coleman, "Corneal pachymetric topography," Ophthalmology 112, 1584-1589 (1994).

Unterhuber, A.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Vakoc, B. J.

Watanabe, Y.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Welge-Luben, U. C.

A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
[CrossRef] [PubMed]

Westphal, V.

S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
[CrossRef] [PubMed]

V. Westphal, A. Rollins, S. Radhakrihnan, and J. A. Izatt, "Correction of geometric and refractive image distortions in optical coherence tomography applying Fermat’s principle," Opt. Express 10, 397-404 (2002).
[PubMed]

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
[PubMed]

Wilkins, J. R.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
[PubMed]

Winter, C.

G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
[CrossRef] [PubMed]

Wirbelauer, C.

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[CrossRef] [PubMed]

Wirtitsch, M.

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
[CrossRef] [PubMed]

Wojtkowski, M.

R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14, 3225-3237 (2006).
[CrossRef] [PubMed]

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
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Yamanari, M.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
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Yang, C. H.

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Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
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Y. Yasuno, V. D. Madjarova, S. Makita, M. Akiba, A. Morosawa, C. Chong, T. Sakai, K. P. Chan, M. Itoh, and T. Yatagai, "Three dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments," Opt. Express 13, 10652-10664 (2005).
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Yatagai, T.

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
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Y. Yasuno, V. D. Madjarova, S. Makita, M. Akiba, A. Morosawa, C. Chong, T. Sakai, K. P. Chan, M. Itoh, and T. Yatagai, "Three dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments," Opt. Express 13, 10652-10664 (2005).
[CrossRef] [PubMed]

Yazdanfar, A.

S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
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Yun, S. H.

H. Lim, J. F. de Boer, B. H. Park, E. C. Lee, R. Yelin, and S. H. Yun, "Optical frequency domain imaging with a rapidly swept laser in the 815-870nm range," Opt. Express 14, 5937-5944 (2006).
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W. Y. Oh, S. H. Yun, G. J. Tearney, and B. E. Bouma, "115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser," Opt. Lett. 30, 3159-3161 (2005).
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B. J. Vakoc, S. H. Yun, J. F. de Boer, G. J. Tearney, and B.E. Bouma, "Phase-resolved optical frequency domain imaging," Opt. Express 13, 5483-5493 (2005).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
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N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29, 480-482 (2004).
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S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822-4828 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B.E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11, 2953-2963 (2003).
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S. H. Yun, C. Boudoux, G. J. Tearney, and B. E. Bouma, "High-speed wavelength-swept source semiconductor laser with a polygon-scanner-based wavelength filter," Opt. Lett. 28, 1981-1983 (2003).
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Yun, S.H.

Am. Acad. Ophthalmol. (2)

S. Kaufman, D. Musch, M. W. Belin, E. J. Cohen, D. Meisler, W. J. Reinhart, I. J. Dell, and W. S. V. Meter, "Confocal Microscopy," Am. Acad. Ophthalmol. 111, 396-406 (2003).

Y. Li, R. Shekhar, and D. Huang, "Corneal Pachymetry Mapping with high-speed Optical Coherence Tomography," Am. Acad. Ophthalmol. 113, 792-799 (2006).

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C. Wirbelauer, C. Scholz, H. Hoerauf, D. Thoai Pham, H. Laqua, and R. Birngruber, "Noncontact Corneal Pachymetry with Slit Lamp-adapted Optical Coherence Tomography," Am. J. Ophthalmol. 133, 444-450 (2002).
[CrossRef] [PubMed]

A. F. Fercher, C. K. Hitzenberger, W. Drexler, G. Kamp, and H. Sattmann, "In-Vivo Optical Coherence Tomography," Am. J. Ophthalmol. 116, 113-115 (1993).
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M. R. Hee, J. A. Izatt, and E. A. Swanson, "Optical coherence tomography of the human retina," Arch. Ophthalmol. 113, 325-332 (1995).
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S. Radhakrishnan, A. M. Rollins, J. E. Roth, A. Yazdanfar, V. Westphal, D. Bardenstein, and J. A. Izatt, "Real-Time Optical Coherence Tomography of the Anterior Segment at 1310nm," Arch. Ophthalmol. 119, 1179-1185 (2001).
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S. Radhakrishnan, J. Goldsmith, D. Huang, V. Westphal, D. K. Dueker, A. M. Rollins, J. A. Izatt, and S. D. Smith, "Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for detection of Narrow Anterior Chamber Angles," Arch. Ophthalmol. 123, 1053-1059 (2005).
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G. Geerling, M. Muller, C. Winter, H. Hoerauf, S. Oelckers, and R. Birngtuber, "Intraoperative 2-Dimensional Optical Coherence Tomography as a New Tool for Anterior Segment Surgery," Arch. Ophthalmol. 123, 253-257 (2005).
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Archives of Ophthalmology (1)

W. Drexler, H. Sattmann, B. Hermann, T. H. Ko, M. Stur, A. Unterhuber, C. Scholda, O. Findl, M. Wirtitsch, J. G. Fujimoto, and A.F. Fercher, "Enhanced visualization of macular pathology with the use of ultrahigh-resolution optical coherence tomography," Archives of Ophthalmology 121, 695-706 (2003).
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G. R. Melles, F. Lander, F. J. Rietveld, L. Remeijer, and W. H. Beekhuis, "A new surgical technique for deep stromal, anterior lamellar keratoplasty," Br. J. Ophthalmol. 83, 327-333 (1999).
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A. S. Neubauer, S. G. Priglinger, M. J. Thiel, C. A. May, and U. C. Welge-Luben, "Sterile structural imaging of donor cornea by Optical Coherence Tomography," Cornea 21, 490-494 (2002).
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Invest. Ophthalmol. Visual Sci. (1)

S. Muscat, N. McKay, S. Parks, E. Kemp, and D. Keating, "Repeatability and reproducibility of corneal thickness measurements by Optical Coherence Tomography," Invest. Ophthalmol. Visual Sci. 43, 1791-1795 (2002).

J. Biomed. Opt. (2)

M. Wojtkowski, R. Leitgeb, A. Kowalczyk, T. Bajraszewski, and A. F. Fercher, "In vivo human retinal imaging by Fourier domain optical domain optical coherence tomography," J. Biomed. Opt. 7, 457-463 (2002).
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S. Haque, T. Simpson, and L. Jones, "Corneal and Epithelial thickness in Keratoconus: A comparison of Ultrasonic Pachymetry, Obscan II, and Optical Coherence Tomography," J. Refractive Surgery 22, (2006).

Nat. Med. (1)

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, "Ultrahigh-resolution ophthalmic optical coherence tomography," Nat. Med. 7, 502-507 (2001).
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Ophthalmology (4)

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
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Opt. Express (14)

V. Westphal, A. Rollins, S. Radhakrihnan, and J. A. Izatt, "Correction of geometric and refractive image distortions in optical coherence tomography applying Fermat’s principle," Opt. Express 10, 397-404 (2002).
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N. Nassif, B. Cense, B. H. Park, M. Pierce, S. H. Yun, B. Bouma, G. Tearney, T. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral domain optical coherence tomography," Opt. Express 12, 367-376 (2004).
[CrossRef] [PubMed]

R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14, 3225-3237 (2006).
[CrossRef] [PubMed]

E. C. W. Lee, J. F. de Boer, M. Mujat, H. Lim, and S.H. Yun, "In vivo optical frequency domain imaging of human retina and choroid," Opt. Express 14, 4403-4411 (2006).
[CrossRef] [PubMed]

H. Lim, J. F. de Boer, B. H. Park, E. C. Lee, R. Yelin, and S. H. Yun, "Optical frequency domain imaging with a rapidly swept laser in the 815-870nm range," Opt. Express 14, 5937-5944 (2006).
[CrossRef] [PubMed]

H. Lim, M. Mujat, C. Kerbage, E. C. Lee, Y. Chen, T. C. Chen, and J. F. de Boer, "High-speed imaging of human retina in vivo with swept source optical coherence tomography," Opt. Express 14, 12902-12908 (2006).
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M. V. Sarunic, M. A. Choma, C. Yang, and J. A. Izatt, "Instantaneous complex conjugate resolved spectral domain and swept-source OCT using 3 by 3 couplers," Opt. Express 13, 957-967 (2005).
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Y. Yasuno, V. D. Madjarova, S. Makita, M. Akiba, A. Morosawa, C. Chong, T. Sakai, K. P. Chan, M. Itoh, and T. Yatagai, "Three dimensional and high-speed swept-source optical coherence tomography for in vivo investigation of human anterior eye segments," Opt. Express 13, 10652-10664 (2005).
[CrossRef] [PubMed]

M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11, 2183-2189 (2003).
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S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B.E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11, 2953-2963 (2003).
[CrossRef]

S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer, "High-speed spectral-domain optical coherence tomography at 1.3μm wavelength," Opt. Express 11, 3598-3604 (2003).
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R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11, 889-894 (2003).
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B. J. Vakoc, S. H. Yun, J. F. de Boer, G. J. Tearney, and B.E. Bouma, "Phase-resolved optical frequency domain imaging," Opt. Express 13, 5483-5493 (2005).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, and B. E. Bouma, "Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting," Opt. Express 12, 4822-4828 (2004).
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Opt. Lett. (5)

Proc. SPIE (1)

Y. Yasuno, M. Yamanari, H. Mori, K. Kawana, Y. Watanabe, M. Miura, A. Miyazawa, T. Oshika, and T. Yatagai, "Clinical examinations of anterior eye segments by three-dimensional swept-source optical coherence tomography," Proc. SPIE 6426, 64260U (2007).
[CrossRef]

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical Coherence Tomography," Science 254, 1178-1181 (1991).
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Supplementary Material (5)

» Media 1: AVI (3581 KB)     
» Media 2: AVI (6675 KB)     
» Media 3: AVI (7968 KB)     
» Media 4: AVI (1859 KB)     
» Media 5: AVI (8498 KB)     

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Figures (8)

Fig. 1.
Fig. 1.

Schematic diagram of the tunable source consists of a scanning filter and a circular cavity. SOA: semiconductor optical amplifier; PC: polarization controller; Circ: Circulator; Col: collimator; FC: fiber coupler. A 12-sided polygon instead of 72-sided one utilized in the experiment is illustrated in the figure.

Fig. 2.
Fig. 2.

(a). Measured spectrum of the output laser cavity with a bandwidth of 135nm in peak hold mode (b) Time response of the laser showing six wavelengths sweeps.

Fig. 3.
Fig. 3.

Schematic diagram of the OFDI system set for imaging the anterior segments. Two AOMs are introduced into the sample and reference arms to obtain a net frequency shift of 21MHz. Circ: fiber circulator; Col: collimator; FBG: fiber Bragg grating; BD: balanced detector; FC: fiber coupler.

Fig. 4.
Fig. 4.

Axial point spread function of a partial reflector placed in the sample arm at different depth locations. An intensity drop of 6dB at ~2mm (dashed line) is measured on each side of the coherence function (in air).

Fig. 5.
Fig. 5.

(3.58 MB) Sequence of 120 images of the cornea anterior segments of the right eye of a healthy volunteer. Each image frame consists of 490 depth profiles and spans a horizontal range of 13.4mm along horizontal (x-axis) and 4.15mm in depth along a vertical scan of 12mm. Total of 120 frames were acquired in 1.4 seconds. [Media 1]

Fig. 6.
Fig. 6.

(6.67 MB) Three dimensional tomography of the anterior segment of the human eye. The volume consist of 490×120×840 pixels spans a volume of (13.4×12×4.1)mm3. [Media 2]

Fig, 7.
Fig, 7.

(1.81 MB) Sequence of 60 images of the (a) cornea [Media 3] and (b) angle structures of the right eye of a human volunteer [Media 4]. Each image consists of 1024 depth profiles acquired at a frame rate of 43 frames per second.

Fig. 7. (c).
Fig. 7. (c).

(8.49 MB) Three dimensional tomography of the angle section of the right eye of a human volunteer. The movie is constructed from 60 frames each consist of 1024 depth profiles. The movie consists of 848×704×60 pixels and spans a volume (5×3.6×5) mm3 of the angle. [Media 5]

Equations (1)

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I ( t ) A S s S r cos [ 2 K z + 2 πΔ ft + ϕ ( z ) ]

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