Abstract

We have developed a compact, multimodal instrument for simultaneous acquisition of en face quasi-confocal fundus images and adaptive-optics (AO) spectral-domain optical coherence tomography (SDOCT) cross-sectional images. The optical system including all AO and SDOCT components occupies a 60×60cm breadboard that can be readily transported for clinical applications. The AO component combines a Hartmann–Shack wavefront sensor and a microelectromechanical systems-based deformable mirror to sense and correct ocular aberrations at 15Hz with a maximum stroke of 4μm. A broadband superluminescent diode source provides 4μm depth resolution for SDOCT imaging. In human volunteer testing, we observed up to an 8dB increase in OCT signal and a corresponding lateral resolution of <10μm as a result of AO correction.

© 2007 Optical Society of America

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