Abstract

We present the development of a continuous-wave method of quantifying the optical properties of a two-layered model of the human head using a broadband spectral approach. Absolute absorption and scattering properties of the upper and lower layers of phantoms with known optical properties were reconstructed from steady-state multi-distance measurements by performing differential fit analysis of the near-infrared reflectance spectrum between 700 and 1000nm. From spectra acquired at 10, 20, and 30mm, the concentration of a chromophore in the bottom layer was determined within an error of 10% in the presence of a 15mm thick top layer. These results demonstrate that our method was able to determine the optical properties of the lower layer, which represents brain, with acceptable error at specific source–detector distances.

© 2010 Optical Society of America

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