Abstract

Cavity-enhanced tunable diode laser absorption spectroscopy is an attractive method for measuring small concentrations of gaseous species. Ethane is a breath biomarker of lipid peroxidation initiated by reactive oxygen species. A noninvasive means of quickly quantifying oxidative stress status has the potential for broad clinical application. We present a simple, compact system using off-axis integrated cavity output spectroscopy with an interband cascade laser and demonstrate its use in real-time measurements of breath ethane. We demonstrate a detection sensitivity of 0.48ppb/Hz1/2.

© 2008 Optical Society of America

Full Article  |  PDF Article
Related Articles
Parts per trillion sensitivity for ethane in air with an optical parametric oscillator cavity leak-out spectrometer

Golo von Basum, Daniel Halmer, Peter Hering, Manfred Mürtz, Stephan Schiller, Frank Müller, Alexander Popp, and Frank Kühnemann
Opt. Lett. 29(8) 797-799 (2004)

Pulsed quantum cascade laser-based cavity ring-down spectroscopy for ammonia detection in breath

Jagadeeshwari Manne, Oleksandr Sukhorukov, Wolfgang Jäger, and John Tulip
Appl. Opt. 45(36) 9230-9237 (2006)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (8)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription