Abstract

The alignment of deposited minerals in tissues such as bone and teeth plays a critical role in the mechanical properties of these tissues. Therefore, assessment of features that are characteristic of aligned biominerals could aid in the development of novel biomaterials and engineered tissues that can be used to replace damaged or defective human tissues. In this study, we demonstrate that light scattering spectroscopy can serve as a useful tool for the noninvasive characterization of mineralization on aligned organic substrates. Specifically, we used silk films with oriented and nonoriented secondary structures as a protein matrix for control of mineralization. The mineral deposits displayed self-affine fractal morphologies with the oriented films yielding a significantly higher Hurst parameter, which in turn suggests higher levels of fractal organization. In addition, the value of the upper bound of fractal correlation lengths was significantly smaller for the oriented than for the nonoriented films and correlated well with the size of the corresponding nanocrystalline mineral beads identified by scanning electron microscope imaging.

© 2009 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Intrinsic fluorescence changes associated with the conformational state of silk fibroin in biomaterial matrices

Irene Georgakoudi, Irene Tsai, Cherry Greiner, Cheryl Wong, Jordy DeFelice, and David Kaplan
Opt. Express 15(3) 1043-1053 (2007)

Biochemical characterization of human gingival crevicular fluid during orthodontic tooth movement using Raman spectroscopy

Gyeong Bok Jung, Kyung-A Kim, Ihn Han, Young-Guk Park, and Hun-Kuk Park
Biomed. Opt. Express 5(10) 3508-3520 (2014)

Silk fibroin diaphragm-based fiber-tip Fabry-Perot pressure sensor

Linghao Cheng, Cengzhong Wang, Yunyun Huang, Hao Liang, and Bai-Ou Guan
Opt. Express 24(17) 19600-19606 (2016)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription