Abstract

The emission and transmission properties of three commercially produced coherent fiber optic imaging bundles were evaluated. Full fluorescence excitation versus emission data were collected from 250 to 650 nm excitation for high-resolution Sumitomo, Fujikura, and Schott fiber bundles. The results generated show regions of autofluorescence and inelastic Raman scattering in the imaging bundles that represent a wavelength-dependent background signal when these fibers are used for imaging applications. The high-resolution fiber bundles also exhibit significant variation in transmission with the angle of illumination, which affects the overall coupling and transmission efficiency. Knowledge of these properties allows users of high-resolution imaging bundles to optimally design systems that utilize such bundles.

© 2008 Optical Society of America

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    [CrossRef]
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    [CrossRef]
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2007 (1)

2006 (1)

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

2005 (3)

2004 (3)

2000 (3)

T. P. Moffitt and S. A. Prahl, “In vivo sized-fiber spectroscopy,” Proc. SPIE 3917, 225-231 (2000).

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

1995 (1)

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

1994 (1)

A. Komiyama and M. Hashimoto, “A new class of crosstalk in image fibers,” Opt. Commun. 107, 49-53 (1994).
[CrossRef]

1992 (1)

M. Ohashi, K. Shiraki, and K. Tajima, “Optical loss property of silica-based single mode fibers,” J. Lightwave Technol. 10, 539-543 (1992).
[CrossRef]

1989 (1)

M. Mogi and K. Yoshimura, “Development of super high density packed image guide,” Proc. SPIE 1067, 172-181 (1989).

1988 (1)

M. A. Player, “Spread functions and modulation transfer functions of fibre-optic bundles,” J. Mod. Opt. 35, 1363-1372 (1988).
[CrossRef]

1982 (1)

1981 (1)

1973 (1)

R. H. Stolen and E. P. Ippen, “Raman gain in glass optical waveguides,” Appl. Phys. Lett. 22, 276-278 (1973).
[CrossRef]

1970 (1)

J. F. Scott, “Raman Spectra of GeO2,” Phys. Rev. B 1, 3488-3493 (1970).

Bin, S. Kung

Botting, S. K.

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

Brands, W. R.

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Brewer, M. A.

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Brookner, C.

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Carlson, K.

Chan, N. Y.

G. S. Kino, T. D. Wang, C. H. Contag, M. Mandella, and N. Y. Chan, “Performance of dual axes confocal microscope for in vivo molecular and cellular imaging,” Proc. SPIE 5324, 35-46 (2004).

Chidley, M.

Christian, D. D.

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

Collier, T.

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Contag, C. H.

G. S. Kino, T. D. Wang, C. H. Contag, M. Mandella, and N. Y. Chan, “Performance of dual axes confocal microscope for in vivo molecular and cellular imaging,” Proc. SPIE 5324, 35-46 (2004).

Descour, M.

Drezek, R.

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Drezek, R. A.

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Dunbar, L. A.

Fatemeh, T.

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

Follen, M.

Gillenwater, A.

Gmitro, A. F.

Gobel, W.

Hashimoto, K.

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

Hashimoto, M.

A. Komiyama and M. Hashimoto, “A new class of crosstalk in image fibers,” Opt. Commun. 107, 49-53 (1994).
[CrossRef]

Helmchen, F.

Hoying, J. B.

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

Ippen, E. P.

R. H. Stolen and E. P. Ippen, “Raman gain in glass optical waveguides,” Appl. Phys. Lett. 22, 276-278 (1973).
[CrossRef]

Kano, A.

Kerr, J. N. D.

Kino, G. S.

G. S. Kino, T. D. Wang, C. H. Contag, M. Mandella, and N. Y. Chan, “Performance of dual axes confocal microscope for in vivo molecular and cellular imaging,” Proc. SPIE 5324, 35-46 (2004).

Kirkpatrick, N. D.

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Komiyama, A.

A. Komiyama and M. Hashimoto, “A new class of crosstalk in image fibers,” Opt. Commun. 107, 49-53 (1994).
[CrossRef]

Kroto, S. M.

Lotan, R.

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Malpica, A.

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Mandella, M.

G. S. Kino, T. D. Wang, C. H. Contag, M. Mandella, and N. Y. Chan, “Performance of dual axes confocal microscope for in vivo molecular and cellular imaging,” Proc. SPIE 5324, 35-46 (2004).

McCabe, E. M.

Moffitt, T. P.

T. P. Moffitt and S. A. Prahl, “In vivo sized-fiber spectroscopy,” Proc. SPIE 3917, 225-231 (2000).

Mogi, M.

M. Mogi and K. Yoshimura, “Development of super high density packed image guide,” Proc. SPIE 1067, 172-181 (1989).

Nakajima, A.

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

Nimmerjahn, A.

Ohashi, M.

M. Ohashi, K. Shiraki, and K. Tajima, “Optical loss property of silica-based single mode fibers,” J. Lightwave Technol. 10, 539-543 (1992).
[CrossRef]

Olivier, C.

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

Player, M. A.

M. A. Player, “Spread functions and modulation transfer functions of fibre-optic bundles,” J. Mod. Opt. 35, 1363-1372 (1988).
[CrossRef]

Prahl, S. A.

T. P. Moffitt and S. A. Prahl, “In vivo sized-fiber spectroscopy,” Proc. SPIE 3917, 225-231 (2000).

Presby, H. M.

Raighne, A. M.

Ramiro, C.

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

Reichenbach, K. L.

Rene-Paul, S.

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

Richards-Kortum, R.

K. Carlson, M. Chidley, S. Kung Bin, M. Descour, A. Gillenwater, M. Follen, and R. Richards-Kortum, “In vivo fiber-optic confocal reflectance microscope with an injection-molded plastic miniature objective lens,” Appl. Opt. 44, 1792-1797 (2005).
[CrossRef]

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Rouse, A. R.

Scharf, T.

Scott, J. F.

J. F. Scott, “Raman Spectra of GeO2,” Phys. Rev. B 1, 3488-3493 (1970).

Shiraki, K.

M. Ohashi, K. Shiraki, and K. Tajima, “Optical loss property of silica-based single mode fibers,” J. Lightwave Technol. 10, 539-543 (1992).
[CrossRef]

Stolen, R. H.

R. H. Stolen and E. P. Ippen, “Raman gain in glass optical waveguides,” Appl. Phys. Lett. 22, 276-278 (1973).
[CrossRef]

Sun, R.-D.

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

Tajima, K.

M. Ohashi, K. Shiraki, and K. Tajima, “Optical loss property of silica-based single mode fibers,” J. Lightwave Technol. 10, 539-543 (1992).
[CrossRef]

Udovich, J. A.

Utzinger, U.

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Wang, T. D.

G. S. Kino, T. D. Wang, C. H. Contag, M. Mandella, and N. Y. Chan, “Performance of dual axes confocal microscope for in vivo molecular and cellular imaging,” Proc. SPIE 5324, 35-46 (2004).

Watanabe, I.

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

Watanabe, T.

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

Weiss, J. A.

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

Xu, C.

Yang, L.

Yoshimura, K.

M. Mogi and K. Yoshimura, “Development of super high density packed image guide,” Proc. SPIE 1067, 172-181 (1989).

Yuen, M. J.

Zou, C.

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Am. J. Obstet. Gynecol. (1)

R. Drezek, T. Collier, C. Brookner, A. Malpica, R. Lotan, and R. Richards-Kortum, “Laser scanning confocal microscopy of cervical tissue before and after application of acetic acid,” Am. J. Obstet. Gynecol. 182, 1135-1139 (2000).

Appl. Opt. (5)

Appl. Phys. Lett. (1)

R. H. Stolen and E. P. Ippen, “Raman gain in glass optical waveguides,” Appl. Phys. Lett. 22, 276-278 (1973).
[CrossRef]

J Biomed. Opt. (1)

N. D. Kirkpatrick, J. B. Hoying, S. K. Botting, J. A. Weiss, and U. Utzinger, “In vitro model for endogenous optical signatures of collagen,” J Biomed. Opt. 11, 054021 (2006).
[CrossRef]

J. Lightwave Technol. (1)

M. Ohashi, K. Shiraki, and K. Tajima, “Optical loss property of silica-based single mode fibers,” J. Lightwave Technol. 10, 539-543 (1992).
[CrossRef]

J. Mod. Opt. (1)

M. A. Player, “Spread functions and modulation transfer functions of fibre-optic bundles,” J. Mod. Opt. 35, 1363-1372 (1988).
[CrossRef]

J. Photochem. Photobiol., A (1)

R.-D. Sun, A. Nakajima, I. Watanabe, T. Watanabe, and K. Hashimoto, “TiO2-coated optical fiber bundles used as a photocatalytic filter for decomposition of gaseous organic compounds,” J. Photochem. Photobiol., A 136, 111-116 (2000).

Opt. Commun. (1)

A. Komiyama and M. Hashimoto, “A new class of crosstalk in image fibers,” Opt. Commun. 107, 49-53 (1994).
[CrossRef]

Opt. Eng. (1)

C. Ramiro, C. Olivier, D. D. Christian, T. Fatemeh, and S. Rene-Paul, “Measurements of the point spread function for multicore fibers used as image guides in microendoscopy,” Opt. Eng. 34, 2092-2102 (1995).

Opt. Express (1)

Opt. Lett. (1)

Photochem. Photobiol. (1)

N. D. Kirkpatrick, C. Zou, M. A. Brewer, W. R. Brands, R. A. Drezek, and U. Utzinger, “Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring,” Photochem. Photobiol. 81, 125-134 (2005).
[CrossRef]

Phys. Rev. B (1)

J. F. Scott, “Raman Spectra of GeO2,” Phys. Rev. B 1, 3488-3493 (1970).

Proc. SPIE (3)

G. S. Kino, T. D. Wang, C. H. Contag, M. Mandella, and N. Y. Chan, “Performance of dual axes confocal microscope for in vivo molecular and cellular imaging,” Proc. SPIE 5324, 35-46 (2004).

T. P. Moffitt and S. A. Prahl, “In vivo sized-fiber spectroscopy,” Proc. SPIE 3917, 225-231 (2000).

M. Mogi and K. Yoshimura, “Development of super high density packed image guide,” Proc. SPIE 1067, 172-181 (1989).

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