Abstract

An optical detection setup consisting of a focused laser beam fed into a downstream Fabry–Perot interferometer (FPI) for demodulation of acoustically generated optical phase variations is investigated for its applicability in photoacoustic tomography. The device measures the time derivative of acoustic signals integrated along the beam. Compared to a setup where the detection beam is part of a Mach–Zehnder interferometer, the signal-to-noise ratio of the FPI is lower, but the image quality of the two devices is similar. Using the FPI in a photoacoustic tomograph allows scanning the probe beam around the imaging object without moving the latter.

© 2011 Optical Society of America

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  1. M. H. Xu and L. V. Wang, Rev. Sci. Instrum. 77, 041101(2006).
    [CrossRef]
  2. E. Z. Zhang, J. Laufer, and P. Beard, Appl. Opt. 47, 561(2008).
    [CrossRef] [PubMed]
  3. S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
    [CrossRef] [PubMed]
  4. R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
    [CrossRef]
  5. M. H. Xu and L. V. Wang, Phys. Rev. E 67, 056605 (2003).
    [CrossRef]
  6. M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
    [CrossRef]
  7. P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
    [CrossRef] [PubMed]
  8. G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Appl. Opt. 46, 3352 (2007).
    [CrossRef] [PubMed]
  9. R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
    [CrossRef] [PubMed]
  10. H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
    [CrossRef] [PubMed]
  11. M. Haltmeier and G. Zangerl, Inverse Probl. 26, 125002(2010).
    [CrossRef]
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    [CrossRef]
  13. R. J. Dewhurst and Q. Shan, Meas. Sci. Technol. 5, 655(1994).
    [CrossRef]
  14. P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
    [CrossRef]
  15. M. H. Xu and L. V. Wang, Phys. Rev. E 71, 016706 (2005).
    [CrossRef]
  16. G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
    [CrossRef]

2010 (3)

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

M. Haltmeier and G. Zangerl, Inverse Probl. 26, 125002(2010).
[CrossRef]

2008 (1)

2007 (3)

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Appl. Opt. 46, 3352 (2007).
[CrossRef] [PubMed]

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
[CrossRef]

2006 (1)

M. H. Xu and L. V. Wang, Rev. Sci. Instrum. 77, 041101(2006).
[CrossRef]

2005 (3)

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
[CrossRef] [PubMed]

M. H. Xu and L. V. Wang, Phys. Rev. E 71, 016706 (2005).
[CrossRef]

2004 (1)

M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
[CrossRef]

2003 (1)

M. H. Xu and L. V. Wang, Phys. Rev. E 67, 056605 (2003).
[CrossRef]

2000 (1)

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

1998 (1)

J. D. Hamilton and M. O’Donnel, IEEE Trans. Ultrason. Ferroelect. Freq. Control 45, 216 (1998).
[CrossRef]

1994 (1)

R. J. Dewhurst and Q. Shan, Meas. Sci. Technol. 5, 655(1994).
[CrossRef]

Bauer-Marschallinger, J.

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

Beard, P.

Berer, T.

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

Burgholzer, P.

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Appl. Opt. 46, 3352 (2007).
[CrossRef] [PubMed]

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
[CrossRef]

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
[CrossRef]

Dewhurst, R. J.

R. J. Dewhurst and Q. Shan, Meas. Sci. Technol. 5, 655(1994).
[CrossRef]

Grossauer, H.

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

Grun, H.

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

Grün, H.

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

Haltmeier, M.

M. Haltmeier and G. Zangerl, Inverse Probl. 26, 125002(2010).
[CrossRef]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Appl. Opt. 46, 3352 (2007).
[CrossRef] [PubMed]

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
[CrossRef]

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
[CrossRef]

Hamilton, J. D.

J. D. Hamilton and M. O’Donnel, IEEE Trans. Ultrason. Ferroelect. Freq. Control 45, 216 (1998).
[CrossRef]

Hofacker, P. J.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Hofer, C.

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

Holotta, M.

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

Kharine, A.

S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
[CrossRef] [PubMed]

Kise, W. L.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Kremser, C.

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

Kruger, G. A.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Kruger, R. A.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Laufer, J.

Manohar, S.

S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
[CrossRef] [PubMed]

Miller, K. D.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Nuster, R.

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Appl. Opt. 46, 3352 (2007).
[CrossRef] [PubMed]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
[CrossRef]

O’Donnel, M.

J. D. Hamilton and M. O’Donnel, IEEE Trans. Ultrason. Ferroelect. Freq. Control 45, 216 (1998).
[CrossRef]

Paltauf, G.

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Appl. Opt. 46, 3352 (2007).
[CrossRef] [PubMed]

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
[CrossRef]

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
[CrossRef]

Reinicke, D. R.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Reynolds, H. E.

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Scherzer, O.

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
[CrossRef]

Shan, Q.

R. J. Dewhurst and Q. Shan, Meas. Sci. Technol. 5, 655(1994).
[CrossRef]

Steenbergen, W.

S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
[CrossRef] [PubMed]

Van Leeuwen, T. G.

S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
[CrossRef] [PubMed]

Wang, L. V.

M. H. Xu and L. V. Wang, Rev. Sci. Instrum. 77, 041101(2006).
[CrossRef]

M. H. Xu and L. V. Wang, Phys. Rev. E 71, 016706 (2005).
[CrossRef]

M. H. Xu and L. V. Wang, Phys. Rev. E 67, 056605 (2003).
[CrossRef]

Xu, M. H.

M. H. Xu and L. V. Wang, Rev. Sci. Instrum. 77, 041101(2006).
[CrossRef]

M. H. Xu and L. V. Wang, Phys. Rev. E 71, 016706 (2005).
[CrossRef]

M. H. Xu and L. V. Wang, Phys. Rev. E 67, 056605 (2003).
[CrossRef]

Zangerl, G.

M. Haltmeier and G. Zangerl, Inverse Probl. 26, 125002(2010).
[CrossRef]

Zhang, E. Z.

Appl. Opt. (2)

IEEE Trans. Ultrason. Ferroelect. Freq. Control (1)

J. D. Hamilton and M. O’Donnel, IEEE Trans. Ultrason. Ferroelect. Freq. Control 45, 216 (1998).
[CrossRef]

IEEE Trans. Ultrason. Ferroelectr. Freq. Control (1)

P. Burgholzer, C. Hofer, G. Paltauf, M. Haltmeier, and O. Scherzer, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 52, 1577 (2005).
[CrossRef] [PubMed]

Inverse Probl. (4)

M. Haltmeier and G. Zangerl, Inverse Probl. 26, 125002(2010).
[CrossRef]

M. Haltmeier, O. Scherzer, P. Burgholzer, and G. Paltauf, Inverse Probl. 20, 1663 (2004).
[CrossRef]

P. Burgholzer, J. Bauer-Marschallinger, H. Grun, M. Haltmeier, and G. Paltauf, Inverse Probl. 23, 65 (2007).
[CrossRef]

G. Paltauf, R. Nuster, M. Haltmeier, and P. Burgholzer, Inverse Probl. 23, S81 (2007).
[CrossRef]

J. Biomed. Opt. (2)

R. Nuster, M. Holotta, C. Kremser, H. Grossauer, P. Burgholzer, and G. Paltauf, J. Biomed. Opt. 15, 021307(2010).
[CrossRef] [PubMed]

H. Grün, T. Berer, P. Burgholzer, R. Nuster, and G. Paltauf, J. Biomed. Opt. 15, 021306 (2010).
[CrossRef] [PubMed]

Meas. Sci. Technol. (1)

R. J. Dewhurst and Q. Shan, Meas. Sci. Technol. 5, 655(1994).
[CrossRef]

Phys. Med. Biol. (1)

S. Manohar, A. Kharine, W. Steenbergen, and T. G. Van Leeuwen, Phys. Med. Biol. 50, 2543 (2005).
[CrossRef] [PubMed]

Phys. Rev. E (2)

M. H. Xu and L. V. Wang, Phys. Rev. E 71, 016706 (2005).
[CrossRef]

M. H. Xu and L. V. Wang, Phys. Rev. E 67, 056605 (2003).
[CrossRef]

Proc. SPIE (1)

R. A. Kruger, W. L. Kise, Jr., K. D. Miller, H. E. Reynolds, D. R. Reinicke, G. A. Kruger, and P. J. Hofacker, Proc. SPIE 3916, 150 (2000).
[CrossRef]

Rev. Sci. Instrum. (1)

M. H. Xu and L. V. Wang, Rev. Sci. Instrum. 77, 041101(2006).
[CrossRef]

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Figures (3)

Fig. 1
Fig. 1

Simultaneous detection of pressure and its temporal derivation using a combined CFPI and MZI setup.

Fig. 2
Fig. 2

(a) Temporal signals recorded with the combined MZI–CFPI setup and (b) normalized amplitude spectra S CFPI and S MZI with the experimentally and theoretically obtained CFPI transfer functions T F Exp and TF Sim .

Fig. 3
Fig. 3

Raw data recorded along an x scan with (a) the MZI and (b) the CFPI. Reconstructed projection images of the initial pressures source: (c) using pressure signals recorded with the MZI and (d) using the time derivative of pressure signals recorded with the CFPI.

Equations (1)

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p 0 ( x , y ) = 2 π C 0 n 0 d [ t = d / c S 1 c S · c S 2 t 2 d 2 b ( x D , y D , t ) d t ] d C 0 , with b ( x D , y D , t ) = p ˙ ( x D , y D , t ) t p ( x D , y D , t ) t 2 ,

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