Abstract

The purpose of this Letter is to design, develop, fabricate, and test in clinical trials a new (to our knowledge) type of contact lenses that provides simultaneous near and distance focused vision for presbyopic subjects, including those with up to 2.00 diopters (D) of regular/irregular astigmatism, as an alternative to multifocal contact lenses. The purpose is obtained by generating an optical pattern on the front surface of contact lenses, capable of extending the depth of focus of lenses by 3.00 D with high visual contrast. The pattern was fabricated on top of contact lenses and tested by the use of an eye simulation as well as in clinical trials. Use of the extended depth of focus contact lens enabled patients to achieve good visual acuity and contrast sensitivity for both distance and near vision without compromising the energy distribution or the visual fields.

© 2009 Optical Society of America

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References

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T. Callina and T. P. Reynolds, Ophthalmol. Clin. North Am. 19, 25 (2006).
[PubMed]

S. Radu, Oftalmologia 50, 59 (2006).
[PubMed]

Z. Zalevsky, A. Shemer, A. Zlotnik, E. Ben Eliezer, and E. Marom, Opt. Express 14, 2631 (2006).
[CrossRef] [PubMed]

2005 (1)

2003 (1)

E. Ben-Eliezer, Z. Zalevsky, E. Marom, and N. Konforti, Pure Appl. Opt. 5, S164 (2003).
[CrossRef]

2001 (1)

2000 (1)

J. D. Atwood, Curr. Opin. Ophthalmol. 11, 296 (2000).
[CrossRef] [PubMed]

1998 (1)

Y. S. Rabinowitz, Surv. Ophthalmol. 42, 297 (1998).
[CrossRef] [PubMed]

1997 (1)

1996 (1)

1995 (1)

1990 (1)

1989 (1)

Atwood, J. D.

J. D. Atwood, Curr. Opin. Ophthalmol. 11, 296 (2000).
[CrossRef] [PubMed]

Belkin, M.

Ben Eliezer, E.

Ben Yaish, S.

Ben-Eliezer, E.

E. Ben-Eliezer, E. Marom, N. Konforti, and Z. Zalevsky, Appl. Opt. 44, 2792 (2005).
[CrossRef] [PubMed]

E. Ben-Eliezer, Z. Zalevsky, E. Marom, and N. Konforti, Pure Appl. Opt. 5, S164 (2003).
[CrossRef]

Berriel-Valdos, L. R.

Brennan, N. A.

Callina, T.

T. Callina and T. P. Reynolds, Ophthalmol. Clin. North Am. 19, 25 (2006).
[PubMed]

Castaneda, J. O.

Cathey, W. T.

Chi, W.

Deaver, D.

Diaz, A.

Dowski, E.

Dowski, E. R.

George, N.

Konforti, N.

E. Ben-Eliezer, E. Marom, N. Konforti, and Z. Zalevsky, Appl. Opt. 44, 2792 (2005).
[CrossRef] [PubMed]

E. Ben-Eliezer, Z. Zalevsky, E. Marom, and N. Konforti, Pure Appl. Opt. 5, S164 (2003).
[CrossRef]

Liou, H.

Marom, E.

Rabinowitz, Y. S.

Y. S. Rabinowitz, Surv. Ophthalmol. 42, 297 (1998).
[CrossRef] [PubMed]

Radu, S.

S. Radu, Oftalmologia 50, 59 (2006).
[PubMed]

Reynolds, T. P.

T. Callina and T. P. Reynolds, Ophthalmol. Clin. North Am. 19, 25 (2006).
[PubMed]

Shemer, A.

Taylor, M.

Tepichin, E.

Van der Gracht, J.

Yehezkel, O.

Zalevsky, Z.

Zlotnik, A.

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Figures (4)

Fig. 1
Fig. 1

Simulation of a 3 mm diameter pupil. Solid curve, near field; dashed curve, far field. (a) With and (b) without the EDOF pattern. (c) MTF charts for near and far fields. (d) Simulating decentration: (1)–(4) near field; (5)–(8) far field; (1), (5) 3 mm pupil, no decentration; (2), (6) 4 mm pupil, no decentration; (3), (7) 3 mm pupil, 0.5 mm decentration; (4), (8) 4 mm pupil, 0.5 mm decentration.

Fig. 2
Fig. 2

Clinical testing of presbyopic volunteers. (a) Near-vision performance with and without an EDOF contact lens. (b) Far vision shown with and without EDOF.

Fig. 3
Fig. 3

Results of contrast sensitivity testing for the near field (values are mean ± standard deviation, n = 10 ). The curves are not statistically different ( P > 0.05 , paired t-test).

Fig. 4
Fig. 4

(a) Astigmatic subjects tested for distance vision while not using their required astigmatic correction. Bars represent the degree of cylinder, replaced by the EDOF profile. (b) Amount of negative correction subtracted by the EDOF profile from the far-field correction while a VA of 6 6 is maintained.

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