Estimating optical properties in layered tissues by use of the Born approximation of the radiative transport equation

Abstract

We use the Born approximation of the radiative transport equation to recover simultaneously the absorption and scattering coefficients in a single layer of a two-layer tissue sample from reflectance data. This method reduces the estimation of both optical properties to a single linear, least-squares problem. It is valid over length scales smaller than a transport mean free path and hence is useful for epithelial tissue layers. We demonstrate the accuracy of this method by using spatially resolved reflectance data computed with Monte Carlo simulations.

© 2006 Optical Society of America

Sequential estimation of optical properties of a two-layered epithelial tissue model from depth-resolved ultraviolet-visible diffuse reflectance spectra

Quan Liu and Nirmala Ramanujam
Appl. Opt. 45(19) 4776-4790 (2006)

Determination of the optical properties of a two-layer tissue model by detecting photons migrating at progressively increasing depths

Yasser S. Fawzi, Abo-Bakr M. Youssef, Mohamed H. El-Batanony, and Yasser M. Kadah
Appl. Opt. 42(31) 6398-6411 (2003)

Influence of layered tissue architecture on estimates of tissue optical properties obtained from spatially resolved diffuse reflectometry

Thomas J. Farrell, Michael S. Patterson, and Matthias Essenpreis
Appl. Opt. 37(10) 1958-1972 (1998)

Reliable recovery of the optical properties of multi-layer turbid media by iteratively using a layered diffusion model at multiple source-detector separations

Yu-Kai Liao and Sheng-Hao Tseng
Biomed. Opt. Express 5(3) 975-989 (2014)

Accuracy of the diffusion approximation in determining the optical properties of a two-layer turbid medium

George Alexandrakis, Thomas J. Farrell, and Michael S. Patterson
Appl. Opt. 37(31) 7401-7409 (1998)