Abstract

We report a Koehler-illumination-based full-field, actively stabilized, low-coherence phase-shifting interferometer, which is built on a white-light Michelson interferometer. By using a phase-stepping technique we can obtain full-field phase images of the sample. An actively stabilized phase-lock circuit is employed in the system to reduce phase noise. An application to human epithelial cells (HeLa cells) is achieved in our experiment. The advancement of this technique rests in its ability to take images of unstained biological samples quantitatively and on a nanometer scale.

© 2006 Optical Society of America

Full Article  |  PDF Article
Related Articles
Ultrahigh-resolution full-field optical coherence tomography

Arnaud Dubois, Kate Grieve, Gael Moneron, Romain Lecaque, Laurent Vabre, and Claude Boccara
Appl. Opt. 43(14) 2874-2883 (2004)

Quantitative phase imaging using actively stabilized phase-shifting low-coherence interferometry

Hidenao Iwai, Christopher Fang-Yen, Gabriel Popescu, Adam Wax, Kamran Badizadegan, Ramachandra R. Dasari, and Michael S. Feld
Opt. Lett. 29(20) 2399-2401 (2004)

Low-coherent quantitative phase microscope for nanometer-scale measurement of living cells morphology

Toyohiko Yamauchi, Hidenao Iwai, Mitsuharu Miwa, and Yutaka Yamashita
Opt. Express 16(16) 12227-12238 (2008)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (4)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription