Abstract

We use optical coherence tomography (OCT) to measure glucose-induced changes in Intralipid and in mouse skin samples in vitro. Mouse skin samples are cultured in a CO2 incubator before measurements are made with different amounts of added glucose concentrations. The results show that the glucose-induced changes in the OCT slope value vary between 20%  and  52%30mM glucose in different mouse skin samples. This change is much larger than the change in 2% Intralipid (2.1%/30  mM) and in 5% Intralipid (0.86%30mM). Hence the results show that OCT has potential to monitor glucose-induced changes in tissues in vitro.

© 2006 Optical Society of America

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