July 2009
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Surface-enhanced Raman scattering biosensor for DNA detection on nanoparticle island substrates
Surface-enhanced Raman scattering (SERS) is a leading strategy to achieve high sensitivity for gene detection and identification. However, the acceptance of SERS as a general analytical tool has been hindered somewhat by the lack of systematic development of substrate technology. This work presents a study on the SERS properties of novel engineered silver nanoparticle island substrates and their applications for target oligonucleotide detection.
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Article Information
Surface-enhanced Raman scattering biosensor for DNA detection on nanoparticle island substrates
Wu Yuan, Ho Pui Ho, Rebecca K. Y. Lee, and Siu Kai Kong
Appl. Opt. 48(22) 4329-4337 (2009) View: Abstract | HTML | PDF