Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group
Journal Home About Issues in Progress Current Issue All Issues Early Posting

Low photobleaching and high emission depletion efficiency: the potential of AIE luminogen as fluorescent probe for STED microscopy

Jiaxin Yu, Xianhe Sun, Fuhong Cai, Zhenfeng Zhu, Anjun Qin, Jun Qian, Benzhong Tang, and Sailing He

Not Accessible

Your library or personal account may give you access

Abstract

We present a preliminary study which explores the potential of aggregation-induced emission (AIE) luminogen as a new fluorescent probe for STED microscopy. Compared with Coumarin 102, which is a commonly used organic fluorophore in STED microscopy, HPS, a typical AIE luminogen, is more resistant to photobleaching. In addition, HPS-doped nanoparticles have higher emission depletion efficiency than Coumarin 102 in organic solution. These two advantages of AIE luminogen can facilitate the improvement of spatial resolution, as well as long-term imaging, in STED microscopy. AIE luminogen will be a promising candidate for STED microscopy in the future.

© 2015 Optical Society of America

Full Article  |  PDF Article
More Like This
Long-term two-photon neuroimaging with a photostable AIE luminogen

Jun Qian, Zhenfeng Zhu, Chris Wai Tung Leung, Wang Xi, Liling Su, Guangdi Chen, Anjun Qin, Ben Zhong Tang, and Sailing He
Biomed. Opt. Express 6(4) 1477-1486 (2015)

Optical depletion mechanism of upconverting luminescence and its potential for multi-photon STED-like microscopy

Ruitao Wu, Qiuqiang Zhan, Haichun Liu, Xuanyuan Wen, Baoju Wang, and Sailing He
Opt. Express 23(25) 32401-32412 (2015)

Dual-color three-dimensional STED microscopy with a single high-repetition-rate laser

Kyu Young Han and Taekjip Ha
Opt. Lett. 40(11) 2653-2656 (2015)

View More...

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters
Select Topics Cancel
Top
       
© Copyright 2024 | Optica Publishing Group. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies.
Privacy | Terms of Use