Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Cerebrovascular imaging in vivo by non-contact photoacoustic microscopy based on photoacoustic remote sensing with a laser diode for interrogation

Not Accessible

Your library or personal account may give you access

Abstract

Photoacoustic microscopy (PAM) is a unique tool for biomedical applications because it can visualize optical absorption contrast in vivo. Recently, non-contact PAM based on non-interferometric photoacoustic remote sensing (PARS), termed PARS microscopy, has shown promise for selected imaging applications. A variety of superluminescent diodes (SLDs) have been employed in the PARS microscopy system as the interrogation light source. Here, we investigate the use of a low-cost laser diode (LD) as the interrogation light source in PARS microscopy, termed PARS-LD. A side-by-side comparison of PARS-LD and a PARS microscopy system using an SLD was conducted that showed comparable performance in terms of resolution and signal-to-noise ratio. More importantly, for the first time to our knowledge, in vivo PAM imaging of mouse brain vessels was conducted in a non-contact manner, and the results show that PARS-LD provides great performance.

© 2021 Optica Publishing Group

Full Article  |  PDF Article
More Like This
Label-free, non-contact, in vivo ophthalmic imaging using photoacoustic remote sensing microscopy

Zohreh Hosseinaee, Layla Khalili, James A. Tummon Simmons, Kevan Bell, and Parsin Haji Reza
Opt. Lett. 45(22) 6254-6257 (2020)

Miniature non-contact photoacoustic probe based on fiber-optic photoacoustic remote sensing microscopy

Jiasheng Zhou, Jingying Zhou, Wei Wang, Siqi Liang, Lili Jing, Shou-Hang Bo, and Sung-Liang Chen
Opt. Lett. 46(22) 5767-5770 (2021)

Dual-modal imaging with non-contact photoacoustic microscopy and fluorescence microscopy

Jiasheng Zhou, Wei Wang, Lili Jing, and Sung-Liang Chen
Opt. Lett. 46(5) 997-1000 (2021)

Supplementary Material (1)

NameDescription
Supplement 1       Supplement 1.

Data availability

Data underlying the results presented in this Letter are available upon request.

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved