Abstract
We propose and demonstrate a method of suppressing four-wave mixing (FWM) in an optical fiber bundle to realize coherent anti-Stokes Raman scattering (CARS) endomicroscopy, which is the leading candidate for a definitive diagnosis of gastrointestinal cancer. Two excitation laser beams with different wavelengths are delivered via different cores to suppress FWM and are then combined with a polarization prism and a dual-wavelength wave plate and are focused to a spot. The background emission from the optical fiber bundle was suppressed to 1/3289, and we demonstrated CARS imaging of a polystyrene bead using the proposed method.
© 2021 Optical Society of America
Full Article | PDF ArticleMore Like This
Zhiyong Wang, Liang Gao, Pengfei Luo, Yaliang Yang, Ahmad A. Hammoudi, Kelvin K. Wong, and Stephen T. C. Wong
Opt. Express 19(9) 7960-7970 (2011)
Niklas M. Lüpken, Thomas Würthwein, Jörn P. Epping, Klaus-J. Boller, and Carsten Fallnich
Opt. Lett. 45(14) 3873-3876 (2020)
Zhiyong Wang, Yongjun Liu, Liang Gao, Yuanxin Chen, Pengfei Luo, Kelvin K. Wong, and Stephen T. C. Wong
Opt. Lett. 36(15) 2967-2969 (2011)