Abstract

A fiber-tetherable non-contact photoacoustic remote sensing microscopy system capable of multiplex functional imaging is reported. By utilizing stimulated Raman scattering within an over-pumped polarization-maintaining single-mode optical fiber, rapid pulse-to-pulse switching (500 kHz) of excitation spectral content is demonstrated and utilized as a photoacoustic excitation source. These rapid acquisitions aim to reduce motion artifacts and facilitate high frame rates appropriate for real-time feedback to users. The system is characterized by estimating blood oxygen saturation in blood-flow phantoms and within a mouse ear in vivo.

© 2019 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Coherence-gated photoacoustic remote sensing microscopy

Kevan L. Bell, Parsin Hajireza, and Roger J. Zemp
Opt. Express 26(18) 23689-23704 (2018)

Real-time handheld optical-resolution photoacoustic microscopy

Parsin Hajireza, Wei Shi, and Roger J. Zemp
Opt. Express 19(21) 20097-20102 (2011)

2  MHz multi-wavelength pulsed laser for functional photoacoustic microscopy

Yizhi Liang, Long Jin, Bai-Ou Guan, and Lidai Wang
Opt. Lett. 42(7) 1452-1455 (2017)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Supplementary Material (1)

NameDescription
» Visualization 1       Simulated Raman scattering spectra produced by non-linear pumping of a single-mode optical fiber. Here the input modulation is slowed to 2 Hz so that the changes to the output spectra can be seen.

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (4)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription