Abstract

We present a miniature probe capable of both optical-resolution (OR) and acoustic-resolution (AR) photoacoustic microscopy. A gradient-index-lens fiber and a multimode fiber are used to deliver light for OR and AR illumination, respectively. The probe achieves lateral resolution of 3.1 μm for OR mode and 46–249 μm (at depth of 1.2–4.3 mm) for AR mode, respectively. The size of the probe attains 3.7 mm in diameter, which can be used for endoscopic applications. In vivo imaging of several different parts of a mouse demonstrates the excellent imaging ability of the probe.

© 2018 Optical Society of America

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Supplementary Material (2)

NameDescription
Visualization 1       3D photoacoustic image of mouse back
Visualization 2       3D photoacoustic image of mouse leg

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