Abstract

Spatial frequency domain imaging (SFDI) is emerging as an important new method in biomedical imaging due to its ability to provide label-free, wide-field tissue optical property maps. Most prior SFDI studies have utilized two spatial frequencies (2fx) for optical property extractions. The use of more than two frequencies (multifx) can vastly improve the accuracy and reduce uncertainties in optical property estimates for some tissue types, but it has been limited in practice due to the slow speed of available inversion algorithms. We present a deep learning solution that eliminates this bottleneck by solving the multifx inverse problem 300× to 100,000× faster, with equivalent or improved accuracy compared to competing methods. The proposed deep learning inverse model will help to enable real-time and highly accurate tissue measurements with SFDI.

© 2018 Optical Society of America

Full Article  |  PDF Article
More Like This
Direct mapping from diffuse reflectance to chromophore concentrations in multi-fx spatial frequency domain imaging (SFDI) with a deep residual network (DRN)

Yanyu Zhao, Yue Deng, Shuhua Yue, Ming Wang, Bowen Song, and Yubo Fan
Biomed. Opt. Express 12(1) 433-443 (2021)

Optical property uncertainty estimates for spatial frequency domain imaging

Vivian Pera, Kavon Karrobi, Syeda Tabassum, Fei Teng, and Darren Roblyer
Biomed. Opt. Express 9(2) 661-678 (2018)

Real-time, wide-field and high-quality single snapshot imaging of optical properties with profile correction using deep learning

Enagnon Aguénounon, Jason T. Smith, Mahdi Al-Taher, Michele Diana, Xavier Intes, and Sylvain Gioux
Biomed. Opt. Express 11(10) 5701-5716 (2020)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Supplementary Material (1)

NameDescription
Visualization 1       Supplementary video shows real-time cuff occlusion measurements for oxy- and deoxy-hemogllobin concentrations, as well as average changes.

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription