Abstract
Photoacoustic imaging couples the chemical specificity of optical absorption with the viewing depth of ultrasound. Systems based on linear array transducers have the versatility to be applied in various (pre-) clinical scenarios but face a trade-off between viewing depth and image resolution depending on transducer frequency and aperture. We propose here a method to disentangle, with precision, small, closely spaced targets with optical spectral contrast, without impairing the imaging depth. Photoacoustic data sets were recorded at two different optical wavelengths. We accurately recovered object separation distances (mean ) from the phase difference between signals across the array, down to a spacing of 1/20th of the system’s beam-formed lateral resolution. The proposed method may enable the translation of super-resolution microscopy to deep tissue imaging.
© 2017 Optical Society of America
Full Article | PDF ArticleMore Like This
Sergey Vilov, Bastien Arnal, and Emmanuel Bossy
Opt. Lett. 42(21) 4379-4382 (2017)
Ajay Dangi, Sumit Agrawal, and Sri-Rajasekhar Kothapalli
Opt. Lett. 44(21) 5326-5329 (2019)
Xin Wang, Zhong Ji, Sihua Yang, and Da Xing
Opt. Lett. 42(21) 4486-4489 (2017)