Abstract

Photoacoustic imaging couples the chemical specificity of optical absorption with the viewing depth of ultrasound. Systems based on linear array transducers have the versatility to be applied in various (pre-) clinical scenarios but face a trade-off between viewing depth and image resolution depending on transducer frequency and aperture. We propose here a method to disentangle, with precision, small, closely spaced targets with optical spectral contrast, without impairing the imaging depth. Photoacoustic data sets were recorded at two different optical wavelengths. We accurately recovered object separation distances (mean error=2.3%±6%) from the phase difference between signals across the array, down to a spacing of 1/20th of the system’s beam-formed lateral resolution. The proposed method may enable the translation of super-resolution microscopy to deep tissue imaging.

© 2017 Optical Society of America

Full Article  |  PDF Article
More Like This
Overcoming the acoustic diffraction limit in photoacoustic imaging by the localization of flowing absorbers

Sergey Vilov, Bastien Arnal, and Emmanuel Bossy
Opt. Lett. 42(21) 4379-4382 (2017)

Photoacoustic endomicroscopy based on a MEMS scanning mirror

Heng Guo, Chaolong Song, Huikai Xie, and Lei Xi
Opt. Lett. 42(22) 4615-4618 (2017)

Photoacoustic imaging of dental implants in a porcine jawbone ex vivo

Donghyun Lee, Sungjo Park, Woo-Chang Noh, Jae-Seung Im, and Chulhong Kim
Opt. Lett. 42(9) 1760-1763 (2017)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription