Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Photoacoustic imaging of sub-diffraction objects with spectral contrast

Not Accessible

Your library or personal account may give you access

Abstract

Photoacoustic imaging couples the chemical specificity of optical absorption with the viewing depth of ultrasound. Systems based on linear array transducers have the versatility to be applied in various (pre-) clinical scenarios but face a trade-off between viewing depth and image resolution depending on transducer frequency and aperture. We propose here a method to disentangle, with precision, small, closely spaced targets with optical spectral contrast, without impairing the imaging depth. Photoacoustic data sets were recorded at two different optical wavelengths. We accurately recovered object separation distances (mean error=2.3%±6%) from the phase difference between signals across the array, down to a spacing of 1/20th of the system’s beam-formed lateral resolution. The proposed method may enable the translation of super-resolution microscopy to deep tissue imaging.

© 2017 Optical Society of America

Full Article  |  PDF Article
More Like This
Overcoming the acoustic diffraction limit in photoacoustic imaging by the localization of flowing absorbers

Sergey Vilov, Bastien Arnal, and Emmanuel Bossy
Opt. Lett. 42(21) 4379-4382 (2017)

Lithium niobate-based transparent ultrasound transducers for photoacoustic imaging

Ajay Dangi, Sumit Agrawal, and Sri-Rajasekhar Kothapalli
Opt. Lett. 44(21) 5326-5329 (2019)

Morphological-adaptive photoacoustic tomography with flexible transducer and flexible orientation light

Xin Wang, Zhong Ji, Sihua Yang, and Da Xing
Opt. Lett. 42(21) 4486-4489 (2017)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved