Abstract

Three-dimensional (3D) printing allows for complex or physiologically realistic phantoms, useful, for example, in developing biomedical imaging methods and for calibrating measured data. However, available 3D printing materials provide a limited range of static optical properties. We overcome this limitation with a new method using stereolithography that allows tuning of the printed phantom’s optical properties to match that of target tissues, accomplished by printing a mixture of polystyrene microspheres and clear photopolymer resin. We show that Mie theory can be used to design the optical properties, and demonstrate the method by fabricating a mouse phantom and imaging it using fluorescence optical diffusion tomography.

© 2016 Optical Society of America

Full Article  |  PDF Article

Corrections

Brian Z. Bentz, Anna G. Bowen, Dergan Lin, Daniel Ysselstein, Davin H. Huston, Jean-Christophe Rochet, and Kevin J. Webb, "Printed optics: phantoms for quantitative deep tissue fluorescence imaging: publisher’s note," Opt. Lett. 41, 5575-5575 (2016)
https://www.osapublishing.org/ol/abstract.cfm?uri=ol-41-23-5575

17 November 2016: Corrections were made to page 5230 and to page 5231.


OSA Recommended Articles
Fabrication and application of heterogeneous printed mouse phantoms for whole animal optical imaging

Brian Z. Bentz, Anmol V. Chavan, Dergan Lin, Esther H. R. Tsai, and Kevin J. Webb
Appl. Opt. 55(2) 280-287 (2016)

Geometrically complex 3D-printed phantoms for diffuse optical imaging

Laura A. Dempsey, Melissa Persad, Samuel Powell, Danial Chitnis, and Jeremy C. Hebden
Biomed. Opt. Express 8(3) 1754-1762 (2017)

Three-dimensional printing of tissue phantoms for biophotonic imaging

Jianting Wang, James Coburn, Chia-Pin Liang, Nicholas Woolsey, Jessica C. Ramella-Roman, Yu Chen, and T. Joshua Pfefer
Opt. Lett. 39(10) 3010-3013 (2014)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (3)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription