Abstract

Focusing light through turbid media represents a highly fascinating challenge in modern biophotonics. The unique capability of opto-acoustics for high-resolution imaging of light absorption contrast in deep tissues can provide a natural and efficient feedback to control light delivery in a scattering medium. While the basic feasibility of using opto-acoustic readings as a feedback mechanism for wavefront shaping has been recently reported, the suggested approaches may require long acquisition times, making them challenging to be translated into realistic tissue environments. In an attempt to significantly accelerate dynamic wavefront shaping capabilities, we present here a feedback-based approach using real-time three-dimensional opto-acoustic imaging assisted with genetic-algorithm-based optimization. The new technique offers robust performance in the presence of noisy measurements and can simultaneously control the scattered wave field in an entire volumetric region.

© 2015 Optical Society of America

Full Article  |  PDF Article
More Like This
Influence of the absorber dimensions on wavefront shaping based on volumetric optoacoustic feedback

X. Luís Deán-Ben, Héctor Estrada, Ali Ozbek, and Daniel Razansky
Opt. Lett. 40(22) 5395-5398 (2015)

Real-time optical manipulation of particles through turbid media

Tong Peng, Runze Li, Sha An, Xianghua Yu, Meiling Zhou, Chen Bai, Yansheng Liang, Ming Lei, Chunmin Zhang, Baoli Yao, and Peng Zhang
Opt. Express 27(4) 4858-4866 (2019)

Sub-acoustic resolution optical focusing through scattering using photoacoustic fluctuation guided wavefront shaping

Marco A. Inzunza-Ibarra, Evolene Premillieu, Clemens Grünsteidl, Rafael Piestun, and Todd W. Murray
Opt. Express 28(7) 9823-9832 (2020)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Supplementary Material (3)

» Media 1: MOV (906 KB)     
» Media 2: MOV (689 KB)     
» Media 3: MOV (625 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (5)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription