Abstract

The extraction of tissue samples during brain needle biopsy can cause life-threatening hemorrhage because of significant blood vessel injury during the procedure. Vessel rupture can have significant consequences for patient health, ranging from transient neurological deficits to death. Here, we present a sub-diffuse optical tomography technique that can be integrated into neurosurgical workflow to detect the presence of blood vessels. A proof-of-concept study performed on a realistic brain tissue phantom is presented and demonstrates that interstitial optical tomography (iOT) can detect several 1 mm diameter high-contrast absorbing objects located <2mm from the needle.

© 2015 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Sensitivity analysis aimed at blood vessels detection using interstitial optical tomography during brain needle biopsy procedures

Julien Pichette, Andréanne Goyette, Fabien Picot, Marie-Andrée Tremblay, Gilles Soulez, Brian C. Wilson, and Frédéric Leblond
Biomed. Opt. Express 6(11) 4238-4254 (2015)

A forward-imaging needle-type OCT probe for image guided stereotactic procedures

Chia-Pin Liang, Jeremiah Wierwille, Thais Moreira, Gary Schwartzbauer, M. Samir Jafri, Cha-Min Tang, and Yu Chen
Opt. Express 19(27) 26283-26294 (2011)

5-ALA fluorescence and laser Doppler flowmetry for guidance in a stereotactic brain tumor biopsy

Neda Haj-Hosseini, Johan C. O. Richter, Peter Milos, Martin Hallbeck, and Karin Wårdell
Biomed. Opt. Express 9(5) 2284-2296 (2018)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (3)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription