Abstract

We report on the use of phase-sensitive optical coherence tomography (PhS-OCT) to detect and track temporal and spatial shear wave propagation within tissue, induced by ultrasound radiation force. Kilohertz-range shear waves are remotely generated in samples using focused ultrasound emission and their propagation is tracked using PhS-OCT. Cross-sectional maps of the local shear modulus are reconstructed from local estimates of shear wave speed in tissue-mimicking phantoms. We demonstrate the feasibility of combining ultrasound radiation force and PhS-OCT to perform high-resolution mapping of the shear modulus.

© 2014 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. R. Muthupillai and R. L. Ehman, Nat. Med. 2, 601 (1996).
    [CrossRef]
  2. A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
    [CrossRef]
  3. J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
    [CrossRef]
  4. M. O’Donnell, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 41, 314 (1994).
    [CrossRef]
  5. A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
    [CrossRef]
  6. M. Fatemi and J. F. Greenleaf, Proc. Natl. Acad. Sci. USA 96, 6603 (1999).
    [CrossRef]
  7. L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
    [CrossRef]
  8. J. Bercoff, M. Muller, M. Tanter, and M. Fink, in IEEE Ultrasonics Symposium (2003), pp. 925–928.
  9. B. F. Kennedy, T. R. Hillman, R. A. McLaughlin, B. C. Quirk, and D. D. Sampson, Opt. Express 17, 21762 (2009).
    [CrossRef]
  10. R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
    [CrossRef]
  11. C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
    [CrossRef]
  12. S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
    [CrossRef]
  13. K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
    [CrossRef]
  14. J. Bercoff, M. Tanter, and M. Fink, Appl. Phys. Lett. 84, 2202 (2004).
    [CrossRef]
  15. X. Liang, M. Orescanin, K. S. Toohey, M. F. Insana, and S. A. Boppart, Opt. Lett. 34, 2894 (2009).
    [CrossRef]
  16. M. Razani, A. Mariampillai, C. Sun, T. W. H. Luk, V. X. D. Yang, and M. C. Kolios, Biomed. Opt. Express 3, 972 (2012).
    [CrossRef]
  17. W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
    [CrossRef]
  18. S. Song, Z. Huang, and R. K. Wang, J. Biomed. Opt. 18, 121505 (2013).
    [CrossRef]
  19. J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
    [CrossRef]
  20. J. McLaughlin and D. Renzi, Inverse Probl. 22, 681 (2006).
    [CrossRef]
  21. D. Royer and E. Dieulesaint, Elastic Waves in Solids I: Free and Guided Propagation (Springer, 2000).
  22. K. R. Nightingale, S. McAleavey, and G. E. Trahey, Ultrasound Med. Biol. 29, 1715 (2003).
    [CrossRef]
  23. J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
    [CrossRef]
  24. T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
    [CrossRef]
  25. M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
    [CrossRef]
  26. M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
    [CrossRef]
  27. E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
    [CrossRef]

2013 (2)

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

S. Song, Z. Huang, and R. K. Wang, J. Biomed. Opt. 18, 121505 (2013).
[CrossRef]

2012 (4)

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

M. Razani, A. Mariampillai, C. Sun, T. W. H. Luk, V. X. D. Yang, and M. C. Kolios, Biomed. Opt. Express 3, 972 (2012).
[CrossRef]

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

2011 (1)

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

2009 (2)

2008 (2)

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

2006 (1)

J. McLaughlin and D. Renzi, Inverse Probl. 22, 681 (2006).
[CrossRef]

2004 (2)

J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
[CrossRef]

J. Bercoff, M. Tanter, and M. Fink, Appl. Phys. Lett. 84, 2202 (2004).
[CrossRef]

2003 (2)

K. R. Nightingale, S. McAleavey, and G. E. Trahey, Ultrasound Med. Biol. 29, 1715 (2003).
[CrossRef]

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

2002 (1)

L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
[CrossRef]

2001 (2)

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
[CrossRef]

1999 (1)

M. Fatemi and J. F. Greenleaf, Proc. Natl. Acad. Sci. USA 96, 6603 (1999).
[CrossRef]

1998 (1)

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

1997 (1)

T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
[CrossRef]

1996 (1)

R. Muthupillai and R. L. Ehman, Nat. Med. 2, 601 (1996).
[CrossRef]

1994 (1)

M. O’Donnell, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 41, 314 (1994).
[CrossRef]

1991 (1)

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Aglyamov, S.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Amromin, E.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Arnal, B.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

Athanasiou, A.

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

Badel, A.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Baranov, S. A.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Bavu, E.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Bercoff, J.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
[CrossRef]

J. Bercoff, M. Tanter, and M. Fink, Appl. Phys. Lett. 84, 2202 (2004).
[CrossRef]

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

J. Bercoff, M. Muller, M. Tanter, and M. Fink, in IEEE Ultrasonics Symposium (2003), pp. 925–928.

Bilgen, M.

T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
[CrossRef]

Boppart, S. A.

Catheline, S.

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
[CrossRef]

Céspedes, I.

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Chaffai, S.

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

Chen, R.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Chen, Z.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Chou, L.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Couade, M.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Dahl, J. J.

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

Deffieux, T.

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

Dieulesaint, E.

D. Royer and E. Dieulesaint, Elastic Waves in Solids I: Free and Guided Propagation (Springer, 2000).

Dresner, M. A.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Ehman, R. L.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

R. Muthupillai and R. L. Ehman, Nat. Med. 2, 601 (1996).
[CrossRef]

Emelianov, S.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Emelianov, S. Y.

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

Fatemi, M.

M. Fatemi and J. F. Greenleaf, Proc. Natl. Acad. Sci. USA 96, 6603 (1999).
[CrossRef]

Felmlee, J. P.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Fink, M.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
[CrossRef]

J. Bercoff, M. Tanter, and M. Fink, Appl. Phys. Lett. 84, 2202 (2004).
[CrossRef]

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
[CrossRef]

J. Bercoff, M. Muller, M. Tanter, and M. Fink, in IEEE Ultrasonics Symposium (2003), pp. 925–928.

Fowlkes, J. B.

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

Frinkley, K. D.

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

Gennisson, J. L.

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

Gennisson, J.-L.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

Greenleaf, J. F.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

M. Fatemi and J. F. Greenleaf, Proc. Natl. Acad. Sci. USA 96, 6603 (1999).
[CrossRef]

Guan, G.

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

Hall, T.

T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
[CrossRef]

Hillman, T. R.

Huang, Z.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

S. Song, Z. Huang, and R. K. Wang, J. Biomed. Opt. 18, 121505 (2013).
[CrossRef]

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

Insana, M.

T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
[CrossRef]

Insana, M. F.

Kennedy, B. F.

Kolios, M. C.

Krouskop, T.

T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
[CrossRef]

Kruse, S. A.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Larin, K. V.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Li, C.

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

Li, J.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Li, X.

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Liang, X.

Liu, G.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Luk, T. W. H.

Mahowald, J. L.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Mallet, V.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Manapuram, R. K.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Manduca, A.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Mariampillai, A.

Mashiatulla, M.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

McAleavey, S.

K. R. Nightingale, S. McAleavey, and G. E. Trahey, Ultrasound Med. Biol. 29, 1715 (2003).
[CrossRef]

McLaughlin, J.

J. McLaughlin and D. Renzi, Inverse Probl. 22, 681 (2006).
[CrossRef]

McLaughlin, R. A.

Menodiado, F. M.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Meunier, M.

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

Montaldo, G.

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

Muller, M.

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
[CrossRef]

J. Bercoff, M. Muller, M. Tanter, and M. Fink, in IEEE Ultrasonics Symposium (2003), pp. 925–928.

Muthupillai, R.

R. Muthupillai and R. L. Ehman, Nat. Med. 2, 601 (1996).
[CrossRef]

Nalpas, B.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Nguyen, T.-M.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

Nightingale, K. R.

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

K. R. Nightingale, S. McAleavey, and G. E. Trahey, Ultrasound Med. Biol. 29, 1715 (2003).
[CrossRef]

K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
[CrossRef]

Nightingale, R. W.

K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
[CrossRef]

O’Donnell, M.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

M. O’Donnell, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 41, 314 (1994).
[CrossRef]

Oliphant, T. E.

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Ophir, J.

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Orescanin, M.

Palmeri, M. L.

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
[CrossRef]

Pol, S.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Ponnekanti, H.

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Qi, W.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Quirk, B. C.

Razani, M.

Reif, R.

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

Renzi, D.

J. McLaughlin and D. Renzi, Inverse Probl. 22, 681 (2006).
[CrossRef]

Royer, D.

D. Royer and E. Dieulesaint, Elastic Waves in Solids I: Free and Guided Propagation (Springer, 2000).

Rudenko, O. V.

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

Sampson, D. D.

Sandrin, L.

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
[CrossRef]

Sarvazyan, A. P.

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

Song, S.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

S. Song, Z. Huang, and R. K. Wang, J. Biomed. Opt. 18, 121505 (2013).
[CrossRef]

Sun, C.

Swanson, S. D.

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

Tanter, M.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
[CrossRef]

J. Bercoff, M. Tanter, and M. Fink, Appl. Phys. Lett. 84, 2202 (2004).
[CrossRef]

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
[CrossRef]

J. Bercoff, M. Muller, M. Tanter, and M. Fink, in IEEE Ultrasonics Symposium (2003), pp. 925–928.

Tardivon, A.

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

Toohey, K. S.

Trahey, G. E.

K. R. Nightingale, S. McAleavey, and G. E. Trahey, Ultrasound Med. Biol. 29, 1715 (2003).
[CrossRef]

K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
[CrossRef]

Vallet-Pichard, A.

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

Wang, M. H.

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

Wang, R. K.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

S. Song, Z. Huang, and R. K. Wang, J. Biomed. Opt. 18, 121505 (2013).
[CrossRef]

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

Wang, S.

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Wong, E. Y.

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

Yang, V. X. D.

Yazdi, Y.

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Zhang, J.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Zhou, Q.

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

Appl. Phys. Lett. (1)

J. Bercoff, M. Tanter, and M. Fink, Appl. Phys. Lett. 84, 2202 (2004).
[CrossRef]

Biomed. Opt. Express (1)

IEEE Trans. Ultrason. Ferroelectr. Freq. Control (4)

M. O’Donnell, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 41, 314 (1994).
[CrossRef]

L. Sandrin, M. Tanter, S. Catheline, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 49, 426 (2002).
[CrossRef]

J. Bercoff, M. Tanter, M. Muller, and M. Fink, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 1523 (2004).
[CrossRef]

T. Hall, M. Bilgen, M. Insana, and T. Krouskop, IEEE Trans. Ultrason. Ferroelectr. Freq. Control 44, 1355 (1997).
[CrossRef]

Inverse Probl. (1)

J. McLaughlin and D. Renzi, Inverse Probl. 22, 681 (2006).
[CrossRef]

J. Acoust. Soc. Am. (1)

K. R. Nightingale, M. L. Palmeri, R. W. Nightingale, and G. E. Trahey, J. Acoust. Soc. Am. 110, 625 (2001).
[CrossRef]

J. Biomed. Opt. (3)

W. Qi, R. Chen, L. Chou, G. Liu, J. Zhang, Q. Zhou, and Z. Chen, J. Biomed. Opt. 17, 110505 (2012).
[CrossRef]

S. Song, Z. Huang, and R. K. Wang, J. Biomed. Opt. 18, 121505 (2013).
[CrossRef]

S. Song, Z. Huang, T.-M. Nguyen, E. Y. Wong, B. Arnal, M. O’Donnell, and R. K. Wang, J. Biomed. Opt. 18, 121509 (2013).
[CrossRef]

J. R. Soc. Interface (1)

C. Li, G. Guan, R. Reif, Z. Huang, and R. K. Wang, J. R. Soc. Interface 9, 831 (2012).
[CrossRef]

Laser Phys. (1)

R. K. Manapuram, S. Aglyamov, F. M. Menodiado, M. Mashiatulla, S. Wang, S. A. Baranov, J. Li, S. Emelianov, and K. V. Larin, Laser Phys. 22, 1439 (2012).
[CrossRef]

Med. Image Anal. (1)

A. Manduca, T. E. Oliphant, M. A. Dresner, J. L. Mahowald, S. A. Kruse, E. Amromin, J. P. Felmlee, J. F. Greenleaf, and R. L. Ehman, Med. Image Anal. 5, 237 (2001).
[CrossRef]

Nat. Med. (1)

R. Muthupillai and R. L. Ehman, Nat. Med. 2, 601 (1996).
[CrossRef]

Opt. Express (1)

Opt. Lett. (1)

Proc. Natl. Acad. Sci. USA (1)

M. Fatemi and J. F. Greenleaf, Proc. Natl. Acad. Sci. USA 96, 6603 (1999).
[CrossRef]

Ultrason. Imag. (1)

J. Ophir, I. Céspedes, H. Ponnekanti, Y. Yazdi, and X. Li, Ultrason. Imag. 13, 111 (1991).
[CrossRef]

Ultrasound Med. Biol. (6)

A. P. Sarvazyan, O. V. Rudenko, S. D. Swanson, J. B. Fowlkes, and S. Y. Emelianov, Ultrasound Med. Biol. 24, 1419 (1998).
[CrossRef]

J. Bercoff, S. Chaffai, M. Tanter, L. Sandrin, S. Catheline, M. Fink, J. L. Gennisson, and M. Meunier, Ultrasound Med. Biol. 29, 1387 (2003).
[CrossRef]

M. Tanter, J. Bercoff, A. Athanasiou, T. Deffieux, J.-L. Gennisson, G. Montaldo, M. Muller, A. Tardivon, and M. Fink, Ultrasound Med. Biol. 34, 1373 (2008).
[CrossRef]

M. L. Palmeri, M. H. Wang, J. J. Dahl, K. D. Frinkley, and K. R. Nightingale, Ultrasound Med. Biol. 34, 546 (2008).
[CrossRef]

E. Bavu, J.-L. Gennisson, M. Couade, J. Bercoff, V. Mallet, M. Fink, A. Badel, A. Vallet-Pichard, B. Nalpas, M. Tanter, and S. Pol, Ultrasound Med. Biol. 37, 1361 (2011).
[CrossRef]

K. R. Nightingale, S. McAleavey, and G. E. Trahey, Ultrasound Med. Biol. 29, 1715 (2003).
[CrossRef]

Other (2)

D. Royer and E. Dieulesaint, Elastic Waves in Solids I: Free and Guided Propagation (Springer, 2000).

J. Bercoff, M. Muller, M. Tanter, and M. Fink, in IEEE Ultrasonics Symposium (2003), pp. 925–928.

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (4)

Fig. 1.
Fig. 1.

Experimental setup for shear wave elastography combining a PhS-OCT system with US radiation force. The bottom left inset shows details of the sample arrangement.

Fig. 2.
Fig. 2.

(a) Snapshots of shear wave propagation at different time steps (the US emission starts at t=0ms and lasts 0.1 ms) in a homogeneous agar phantom. The black arrow indicates the lateral position of the US beam (x=1.3mm). The color scale represents axial displacement magnitude and is superimposed on the B mode image of the medium (gray scale). (b) and (c) Temporal profile and spectral content of the displacement field averaged over the sample depth at different lateral positions.

Fig. 3.
Fig. 3.

(a) Spatio–temporal representation of axial displacements at a given depth. The correlation of two rows distant from dx gives the travel time dt yielding the local shear wave speed cs=dx/dt. (b) Reconstructed shear modulus map (color scale) of a homogeneous 0.5% agar phantom superimposed on the B mode image (gray scale). In both figures, the black arrow indicates the lateral position of the US beam and the dashed line delineates the near-field of the shear wave.

Fig. 4.
Fig. 4.

Results obtained on a bi-layered phantom. (a)–(c) Partial shear modulus maps reconstructed from shear waves generated at different locations. Shear modulus maps (color scale) are superimposed on the B mode image (gray scale). The black arrows indicate the lateral position of the US beam (x=2.3, 1.3, and 0.3 mm, respectively). (d) B mode image of the phantom, made of a 1%-agar top-layer and a 2%-agar bottom-layer. The dashed line delineates the boundary between both layers. (e) Shear modulus map obtained from the combination of the partial maps shown in (a)–(c).

Equations (2)

Equations on this page are rendered with MathJax. Learn more.

Δz(x,z,t)=Δϕ(x,z,t)·λ(4πn),
μ(x,z)=ρcs2(x,z),

Metrics