Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Handheld photoacoustic microscopy to detect melanoma depth in vivo

Not Accessible

Your library or personal account may give you access

Abstract

We developed handheld photoacoustic microscopy (PAM) to detect melanoma and determine tumor depth in nude mice in vivo. Compared to our previous PAM system for melanoma imaging, a new light delivery mechanism is introduced to improve light penetration. We show that melanomas with 4.1 and 3.7 mm thicknesses can be successfully detected in phantom and in in vivo experiments, respectively. With its deep melanoma imaging ability and handheld design, this system can be tested for clinical melanoma diagnosis, prognosis, and surgical planning for patients at the bedside.

© 2014 Optical Society of America

Full Article  |  PDF Article
More Like This
In-vivo imaging of melanoma with simultaneous dual-wavelength acoustic-resolution-based photoacoustic/ultrasound microscopy

Congcong Wang, Lili Guo, Guan Wang, Tong Ye, Bo Wang, Jiaying Xiao, and Xinli Liu
Appl. Opt. 60(13) 3772-3778 (2021)

Toward in vivo biopsy of melanoma based on photoacoustic and ultrasound dual imaging with an integrated detector

Yating Wang, Dong Xu, Sihua Yang, and Da Xing
Biomed. Opt. Express 7(2) 279-286 (2016)

Comparison of photoacoustic imaging and histopathological examination in determining the dimensions of 52 human melanomas and nevi ex vivo

Jenny Hult, Aboma Merdasa, Agnes Pekar-Lukacs, Magne Tordengren Stridh, Azin Khodaverdi, John Albinsson, Bodil Gesslein, Ulf Dahlstrand, Linn Engqvist, Yousef Hamid, Douglas Larsson Albèr, Bertil Persson, Tobias Erlöv, Rafi Sheikh, Magnus Cinthio, and Malin Malmsjö
Biomed. Opt. Express 12(7) 4097-4114 (2021)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (5)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved