Abstract

We developed a reflection-mode optoacoustic mesoscopy system, based on raster-scanning of a custom designed spherically focused ultrasound detector, enabling seamless epi-illumination of the volume imaged. We study the performance of acoustic-resolution mesoscopy operating at an ultrawideband bandwidth of 20–180 MHz. i.e., a frequency band spreading over virtually an order of magnitude. Using tomographic reconstruction we showcase previously unreported, to our knowledge, axial resolutions of 4 μm and transverse resolutions of 18 μm reaching depths of up to 5 mm. We further investigate the frequency-dependence of features seen on the images to understand the implications of ultrawideband measurements. We show the overall imaging performance and the frequency ranges that contribute to observable resolution improvements from phantoms and animals.

© 2014 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
In vivo whole-body optoacoustic scanner with real-time volumetric imaging capacity

Thomas Felix Fehm, Xosé Luís Deán-Ben, Steven James Ford, and Daniel Razansky
Optica 3(11) 1153-1159 (2016)

All-optical optoacoustic microscope based on wideband pulse interferometry

Georg Wissmeyer, Dominik Soliman, Rami Shnaiderman, Amir Rosenthal, and Vasilis Ntziachristos
Opt. Lett. 41(9) 1953-1956 (2016)

The potential of photoacoustic microscopy as a tool to characterize the in vivo degradation of surgical sutures

Juan Aguirre, Jordi Morales-Dalmau, Lutz Funk, Francesc Jara, Pau Turon, and Turgut Durduran
Biomed. Opt. Express 5(8) 2856-2869 (2014)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription