Abstract

In this Letter, we present a novel imaging concept that a single imaging system can image different spectral bands with different aperture sizes. It is achieved by using a filter with different transmitted spectral bands in different annular rings as the aperture stop. This concept will enable more efficient system configurations and practical clinical applications. We have demonstrated this concept with a dual-mode near-infrared fluorescence image guided surgical system.

© 2014 Optical Society of America

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References

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  1. J. Hwang, S. Wachsmann-Hogiu, V. Krishnan Ramanujan, A. G. Nowatzyk, Y. Koronyo, L. K. Medina-Kauwe, Z. Gross, H. B. Gray, and D. L. Farkas, Biomed. Opt. Express 2, 356 (2011).
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    [CrossRef]
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    [CrossRef]
  4. R. Liang, Optical Design for Biomedical Imaging (SPIE, 2011).
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    [CrossRef]
  6. S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
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2013

2012

2011

2009

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

2007

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

Azar, F.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Bajaj, A.

Bedard, N.

Bhattar, V.

Burns, P.

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

Cotero, V. E.

Farkas, D. L.

Frangioni, J. V.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Gibbs-Strauss, S. L.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Gillenwater, A. M.

Gioux, S.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Gray, D. C.

Gray, H. B.

Gross, Z.

Hehir, C. A.

Howe, J.

Hu, A.

Hwang, J.

Khamene, A.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Kianzad, V.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Kim, E. M.

Koronyo, Y.

Krishnan Ramanujan, V.

Liang, R.

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

R. Liang, Optical Design for Biomedical Imaging (SPIE, 2011).

Marcus, M.

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

Matsui, A.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

McLaughlin, P.

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

Medina-Kauwe, L. K.

Ngo, L.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Nowatzyk, A. G.

Ntziachristos, V.

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

Oketokoun, R.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Richards-Kortum, R.

Schulz, R.

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

Schwarz, R. A.

Soh, K.-S.

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

Staudinger, V. P.

Themelis, G.

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

Tkaczyk, T. S.

Troyan, S. L.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Wachsmann-Hogiu, S.

Williams, M. D.

Wong, V.

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

Yazdanfar, S.

Yoo, J. S.

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

Ann. Surg. Oncol.

S. L. Troyan, V. Kianzad, S. L. Gibbs-Strauss, S. Gioux, A. Matsui, R. Oketokoun, L. Ngo, A. Khamene, F. Azar, and J. V. Frangioni, Ann. Surg. Oncol. 16, 10 (2009).
[CrossRef]

Biomed. Opt. Express

J. Biomed. Opt.

G. Themelis, J. S. Yoo, K.-S. Soh, R. Schulz, and V. Ntziachristos, J. Biomed. Opt. 14, 064012 (2009).
[CrossRef]

Proc. SPIE

R. Liang, V. Wong, M. Marcus, P. Burns, and P. McLaughlin, Proc. SPIE 6425, 642502 (2007).
[CrossRef]

Other

R. Liang, Optical Design for Biomedical Imaging (SPIE, 2011).

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Figures (7)

Fig. 1.
Fig. 1.

Aperture filter with different transmission bands in the annual rings.

Fig. 2.
Fig. 2.

(a) Optical and mechanical structure of the customized lens with aperture filter (the outer diameter is 25 mm) and (b) the photograph of the assembled lens.

Fig. 3.
Fig. 3.

MTFs of lens with aperture filter in (a) F/4 visible channel (450–650 nm) and (b) F/1.75 NIR channel (810–890 nm).

Fig. 4.
Fig. 4.

(a) NIR and (b) visible images of aperture filter.

Fig. 5.
Fig. 5.

Transmission spectrum of the aperture filter.

Fig. 6.
Fig. 6.

Depth of field test of the aperture-filter lens on the visible channel with (a) F/1.75 traditional lens, (b) F/4 traditional lens, (c) aperture filter lens, and (d) NIR image with aperture-filter lens.

Fig. 7.
Fig. 7.

ICG solution test. (a) F/1.75 traditional lens, (b) F/4 traditional lens, and (c) aperture-filter lens.

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