Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Flexible endoscope for continuous in vivo multispectral fluorescence lifetime imaging

Not Accessible

Your library or personal account may give you access

Abstract

Fluorescence lifetime imaging (FLIM) offers a noninvasive approach for characterizing the biochemical composition of biological tissue. There has been an increasing interest in the application of multispectral FLIM for medical diagnosis. Central to the clinical translation of FLIM technology is the development of compact and high-speed endoscopy systems. Unfortunately, the predominant multispectral FLIM approaches suffer from limitations that impede the development of endoscopy systems that are suitable for in vivo tissue imaging. We present a compact wide-field time-gated FLIM flexible endoscope capable of continuous lifetime imaging of up to three fluorescence emission bands simultaneously. This endoscope design will facilitate the evaluation of FLIM for in vivo applications.

© 2013 Optical Society of America

Full Article  |  PDF Article
More Like This
High-speed multispectral fluorescence lifetime imaging implementation for in vivo applications

Sebina Shrestha, Brian E. Applegate, Jesung Park, Xudong Xiao, Paritosh Pande, and Javier A. Jo
Opt. Lett. 35(15) 2558-2560 (2010)

Handheld multispectral fluorescence lifetime imaging system for in vivo applications

Shuna Cheng, Rodrigo M. Cuenca, Boang Liu, Bilal H. Malik, Joey M. Jabbour, Kristen C. Maitland, John Wright, Yi-Shing Lisa Cheng, and Javier A. Jo
Biomed. Opt. Express 5(3) 921-931 (2014)

Fluorescence lifetime imaging microscopy: in vivo application to diagnosis of oral carcinoma

Yinghua Sun, Jennifer Phipps, Daniel S. Elson, Heather Stoy, Steven Tinling, Jeremy Meier, Brian Poirier, Frank S. Chuang, D. Gregory Farwell, and Laura Marcu
Opt. Lett. 34(13) 2081-2083 (2009)

Supplementary Material (2)

Media 1: AVI (405 KB)     
Media 2: AVI (571 KB)     

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved