Improving visibility in photoacoustic imaging using dynamic speckle illumination

Abstract

In high-frequency photoacoustic imaging with uniform illumination, homogeneous photoabsorbing structures may be invisible because of their large size or limited-view issues. Here we show that, by exploiting dynamic speckle illumination, it is possible to reveal features that are normally invisible with a photoacoustic system comprised of a 20 MHz linear ultrasound array. We demonstrate imaging of a $\varnothing 5\mathrm{mm}$ absorbing cylinder and a 30 μm black thread arranged in a complex shape. The hidden structures are directly retrieved from photoacoustic images recorded for different random speckle illuminations of the phantoms by assessing the variation in the value of each pixel over the illumination patterns.

© 2013 Optical Society of America

Super-resolution photoacoustic fluctuation imaging with multiple speckle illumination

Thomas Chaigne, Jérôme Gateau, Marc Allain, Ori Katz, Sylvain Gigan, Anne Sentenac, and Emmanuel Bossy
Optica 3(1) 54-57 (2016)

Photoacoustic imaging beyond the acoustic diffraction-limit with dynamic speckle illumination and sparse joint support recovery

Eliel Hojman, Thomas Chaigne, Oren Solomon, Sylvain Gigan, Emmanuel Bossy, Yonina C. Eldar, and Ori Katz
Opt. Express 25(5) 4875-4886 (2017)

Super-resolution photoacoustic microscopy using blind structured illumination

Todd W. Murray, Markus Haltmeier, Thomas Berer, Elisabeth Leiss-Holzinger, and Peter Burgholzer
Optica 4(1) 17-22 (2017)

Light focusing and two-dimensional imaging through scattering media using the photoacoustic transmission matrix with an ultrasound array

Thomas Chaigne, Jérôme Gateau, Ori Katz, Emmanuel Bossy, and Sylvain Gigan
Opt. Lett. 39(9) 2664-2667 (2014)

Gel wax-based tissue-mimicking phantoms for multispectral photoacoustic imaging

Efthymios Maneas, Wenfeng Xia, Olumide Ogunlade, Martina Fonseca, Daniil I. Nikitichev, Anna L. David, Simeon J. West, Sebastien Ourselin, Jeremy C. Hebden, Tom Vercauteren, and Adrien E. Desjardins
Biomed. Opt. Express 9(3) 1151-1163 (2018)