Abstract

In fluorescence diffuse optical tomography (fDOT), the accuracy of reconstructed fluorescence distributions highly depends on the knowledge of the tissue optical heterogeneities for correct modeling of light propagation. Common approaches are to assume homogeneous optical properties or, when structural information is available, assign optical properties to various segmented organs, which is likely to result in inaccurate reconstructions. Furthermore, DOT based only on intensity (continuous wave-DOT) is a nonunique inverse problem, and hence, cannot be used to retrieve simultaneously maps of absorption and diffusion coefficients. We propose a method that reconstructs a single parameter from the excitation measurements, which is used in the fDOT problem to accurately recover fluorescence distribution.

© 2013 Optical Society of America

Full Article  |  PDF Article

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (2)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (14)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription