Abstract

We applied a visible-light spectroscopic optical coherence tomography (vis-OCT) for in vivo retinal oximetry. To extract hemoglobin oxygen saturation (sO2) in individual retinal vessels, we established a comprehensive analytical model to describe optical absorption, optical scattering, and blood cell packing factor in the whole blood and fit the acquired vis-OCT signals from the bottom of each imaged vessel. We found that averaged sO2 values in arterial and venous bloods were 95% and 72%, respectively.

© 2013 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Imaging hemodynamic response after ischemic stroke in mouse cortex using visible-light optical coherence tomography

Siyu Chen, Qi Liu, Xiao Shu, Brian Soetikno, Shanbao Tong, and Hao F. Zhang
Biomed. Opt. Express 7(9) 3377-3389 (2016)

Quantitative microvascular hemoglobin mapping using visible light spectroscopic Optical Coherence Tomography

Shau Poh Chong, Conrad W. Merkle, Conor Leahy, Harsha Radhakrishnan, and Vivek J. Srinivasan
Biomed. Opt. Express 6(4) 1429-1450 (2015)

Noninvasive technique for oximetry of blood in retinal vessels

Fran├žois C. Delori
Appl. Opt. 27(6) 1113-1125 (1988)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (4)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription