Abstract

We present a full range handheld probe type spectral domain optical coherence tomography (SD-OCT) method. Here, the sample arm is composed of a tilted fiber-optic cantilever scanner; thus, the phase shift concurrently occurs while sample scanning. With the phase shift, we could achieve a full range complex-conjugate-free OCT image with no additional phase shifters in the reference arm. To realize this technique, a magnetically actuated probe was adopted. Full range SD-OCT images of a pearl, human fingernail, and human tooth were subsequently obtained using this suggested probe. The scanning range and acquisition speed were 3 mm and 20frames/s, respectively.

© 2012 Optical Society of America

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  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
  10. K. Zhang, Y. Huang, and J. U. Kang, Opt. Eng. 50, 119002 (2011).
    [CrossRef]

2011 (2)

2009 (1)

2007 (1)

2006 (2)

Y. Yasuno, S. Makita, T. Endo, G. Aoki, M. Itoh, and T. Yatagai, Appl. Opt. 45, 1861 (2006).
[CrossRef]

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

2003 (1)

2002 (1)

1995 (1)

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El- Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Aoki, G.

Bajraszewski, T.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

El- Zaiat, S. Y.

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El- Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Endo, T.

Fercher, A. F.

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Fujimoto, J. G.

T. Tsai, B. Potsaid, M. F. Kraus, C. Zhou, Y. K. Tao, J. Hornegger, and J. G. Fujimoto, Biomed. Opt. Express 2, 2438 (2011).
[CrossRef]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Heng, X.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Hitzenberger, C. K.

R. A. Leitgeb, C. K. Hitzenberger, A. F. Fercher, and T. Bajraszewski, Opt. Lett. 28, 2201 (2003).
[CrossRef]

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El- Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Hornegger, J.

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Huang, Y.

K. Zhang, Y. Huang, and J. U. Kang, Opt. Eng. 50, 119002 (2011).
[CrossRef]

Itoh, M.

Kamp, G.

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El- Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Kang, J. U.

K. Zhang, Y. Huang, and J. U. Kang, Opt. Eng. 50, 119002 (2011).
[CrossRef]

Kowalczyk, A.

Kraus, M. F.

Lasser, T.

Lee, B. H.

Leitgeb, R.

Leitgeb, R. A.

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Makita, S.

McDowell, E. J.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Michaely, R.

Min, E. J.

Na, J.

Potsaid, B.

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Ryu, S. Y.

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Sekhar, S. C.

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

Tao, Y. K.

Tsai, T.

Wojtkowski, M.

Wu, J.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Yang, C.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Yaqoob, Z.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Yasuno, Y.

Yatagai, T.

Zhang, K.

K. Zhang, Y. Huang, and J. U. Kang, Opt. Eng. 50, 119002 (2011).
[CrossRef]

Zhou, C.

Appl. Opt. (1)

Biomed. Opt. Express (1)

J. Biomed. Opt. (1)

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Opt. Commun. (1)

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El- Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Opt. Eng. (1)

K. Zhang, Y. Huang, and J. U. Kang, Opt. Eng. 50, 119002 (2011).
[CrossRef]

Opt. Lett. (4)

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef]

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Figures (6)

Fig. 1.
Fig. 1.

Schematic of a full range SD-OCT system based on a fiber-optic probe. C, collimator lens; M, mirror; L, lens; G, grating; FP, fiber-optic probe; S, sample.

Fig. 2.
Fig. 2.

(a) Schematic of the probe. The probe can be subdivided into two major parts: lensed fiber and solenoid-based actuator. (b) Photograph of scanning motion. HeNe laser at 635 nm was used to visualize the scanning motion. S, solenoid; I, iron-bead; LF, lensed fiber; FB, fixed bar.

Fig. 3.
Fig. 3.

(a) Schematic diagram and (b) photograph of fiber end, illustrating the concept of phase offset in a fiber-based scanner. θs, scan angle; θt, tilt angle.

Fig. 4.
Fig. 4.

Graph of optical path length offset of theoretical result (dotted curve) and experimental result (solid curve) with respect to time.

Fig. 5.
Fig. 5.

Flow diagram of full range image reconstruction process: (a) 2D spectral interferogram, (b) result of FFT of spectral interferogram in the lateral direction (dotted red curve indicates spatial frequency filter), (c) complex spectrum obtained after filtering and inverse FFT of (b), (d) full range image after FFT of complex spectrum in the optical wavenumber domain, (e) reconstructed full range image considering fiber motion, and (f) standard overlapping SD-OCT image.

Fig. 6.
Fig. 6.

Full range SD-OCT images of biological samples: (a) standard OCT image and (b) full range image of human fingernail near the nail fold region; (c) standard OCT image and (d) full range image of a human tooth near the dentino-enamel junction.

Equations (1)

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I(ω,t)=IR(ω)+Is(ω,t)+2[IR(ω)Is(ω,t)]1/2cos(Δφs(ω,t)+φ(t)),

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