Abstract

We developed a structured interference optical coherence tomography (SIOCT) to enhance the lateral resolution beyond the diffraction limit. A sinusoidal pattern is created on the interferometric beam with the reference intensity temporally modulated. In the Fourier domain, the high spatial frequencies are shifted into the detectable range, which enhances the lateral resolution beyond the diffraction limit by a factor of 2. The lateral resolution of SIOCT was characterized in our study as ∼5.5  μm, surpassing the diffraction limit ∼9.6  μm as in conventional Fourier-domain optical coherence tomography. SIOCT was demonstrated on phantoms and ex vivo adipose tissues.

© 2012 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Integrated-optics-based swept-source optical coherence tomography

V. Duc Nguyen, N. Weiss, W. Beeker, M. Hoekman, A. Leinse, R. G. Heideman, T. G. van Leeuwen, and J. Kalkman
Opt. Lett. 37(23) 4820-4822 (2012)

Optical coherence tomography for the identification of musculoskeletal structures of the spine: a pilot study

Kathy Beaudette, Mathias Strupler, Fouzi Benboujja, Stefan Parent, Carl-Eric Aubin, and Caroline Boudoux
Biomed. Opt. Express 3(3) 533-542 (2012)

Noninvasive in vivo structural and vascular imaging of human oral tissues with spectral domain optical coherence tomography

Bahar Davoudi, Andras Lindenmaier, Beau A. Standish, Ghassan Allo, Kostadinka Bizheva, and Alex Vitkin
Biomed. Opt. Express 3(5) 826-839 (2012)

More Recommended Articles

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (4)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription