Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

In vivo confocal imaging of fast intrinsic optical signals correlated with frog retinal activation

Not Accessible

Your library or personal account may give you access

Abstract

Using freshly isolated animal retinas, we have conducted a series of experiments to test fast intrinsic optical signals (IOSs) that have time courses comparable to electrophysiological kinetics. In this Letter, we demonstrate the feasibility of in vivo imaging of fast IOSs in intact frogs. A rapid line-scan confocal ophthalmoscope was constructed to achieve high-speed IOS recording. By rejecting out-of-focus background light, the line-scan confocal imager provided the resolution to differentiate individual photoreceptors in vivo. Rapid confocal imaging disclosed robust IOSs with time courses comparable to retinal electroretinogram kinetics. High-resolution IOS images revealed both positive (increasing) and negative (decreasing) light responses, with subcellular complexity.

© 2011 Optical Society of America

Full Article  |  PDF Article
More Like This
High spatiotemporal resolution imaging of fast intrinsic optical signals activated by retinal flicker stimulation

Yang-Guo Li, Qiu-Xiang Zhang, Lei Liu, Franklin R. Amthor, and Xin-Cheng Yao
Opt. Express 18(7) 7210-7218 (2010)

High-speed line-scan confocal imaging of stimulus-evoked intrinsic optical signals in the retina

Yang-Guo Li, Lei Liu, Franklin Amthor, and Xin-Cheng Yao
Opt. Lett. 35(3) 426-428 (2010)

In vivo imaging of intrinsic optical signals in chicken retina with functional optical coherence tomography

Alireza Akhlagh Moayed, Sepideh Hariri, Vivian Choh, and Kostadinka Bizheva
Opt. Lett. 36(23) 4575-4577 (2011)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved