Abstract

A side-scanning fiber probe is a critical component for optical coherence tomography in medical imaging and diagnosis. We propose and fabricate an on-axis rotating probe that performs in situ, circumferential scanning that is shadow-free (not susceptible to shadow effects caused by the motor’s wires). A miniature motor that incorporates a bored-out shaft for the optical fiber is located at the distal end of the probe, which results in a more stable and uniform circumferential scan, free from wire-shadow interference effects. More importantly, this design, novel to our knowledge, compared to other probes avoids the insertion losses introduced by optical coupling components and the multitude of optical interfaces, which is very important for sensing weak signals backscattered from structures deep in the tissue.

© 2011 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
    [CrossRef]
  2. E. Regar, T. G. van Leeuwen, and P. W. Serruys, in Design of an OCT Imaging System for Intravascular Applications (Informa Healthcare, 2007), Chap. 1.3.
  3. M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).
  4. P. R. Herz, Y. Chen, A. D. Aguirre, K. Schneider, P. Hsiung, J. G. Fujimoto, K. Madden, J. Schmitt, J. Goodnow, and C. Petersen, Opt. Lett. 29, 2261 (2004).
    [CrossRef] [PubMed]
  5. J. Su, J. Zhang, L. Yu, and Z. Chen, Opt. Express 15, 10390(2007).
    [CrossRef] [PubMed]
  6. P. H. Tran, S. David, M. Brenner, and Z. Chen, Opt. Lett. 29, 1236 (2004).
    [CrossRef] [PubMed]
  7. L. Wu and H. Xie, J. Micro/Nanolithogr. MEMS MOEMS 8, 013030 (2009).
    [CrossRef]
  8. H. Xie, “Full circumferential scanning OCT intravascular imaging probe based on scanning MEMS mirror,” U.S. patent 7,450,244 (November 11, 2008).
  9. Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
    [CrossRef]
  10. New Scale Technologies, Inc., http://www.newscaletech.com.
  11. C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
    [CrossRef] [PubMed]

2009 (1)

L. Wu and H. Xie, J. Micro/Nanolithogr. MEMS MOEMS 8, 013030 (2009).
[CrossRef]

2008 (2)

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

2007 (1)

2006 (1)

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

2004 (2)

Aguirre, A. D.

Bisaillon, C. E.

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

Brenner, M.

Chen, K. W. S.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Chen, N.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Chen, S.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Chen, Y.

Chen, Z.

Condit, C.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

David, S.

Dufour, M.

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

Feldman, M. D.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Fujimoto, J. G.

Goodnow, J.

Grant, R.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Han, L.-H.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Heng, X.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Herz, P. R.

Hsiung, P.

Kemp, N.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Khairyanto, A.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Kim, E.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Kim, J.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Kumar, K.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Lamouche, G.

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

Maciejko, R.

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

Madden, K.

McDowell, E. J.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Milner, T. E.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Monchalin, J. P.

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

Oh, J. H.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Olivo, M.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Petersen, C.

Premachandran, C. S.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Regar, E.

E. Regar, T. G. van Leeuwen, and P. W. Serruys, in Design of an OCT Imaging System for Intravascular Applications (Informa Healthcare, 2007), Chap. 1.3.

Schmitt, J.

Schneider, K.

Serruys, P. W.

E. Regar, T. G. van Leeuwen, and P. W. Serruys, in Design of an OCT Imaging System for Intravascular Applications (Informa Healthcare, 2007), Chap. 1.3.

Sheppard, C. J. R.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Singh, J.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Su, J.

Tran, P. H.

van Leeuwen, T. G.

E. Regar, T. G. van Leeuwen, and P. W. Serruys, in Design of an OCT Imaging System for Intravascular Applications (Informa Healthcare, 2007), Chap. 1.3.

Wu, J.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Wu, L.

L. Wu and H. Xie, J. Micro/Nanolithogr. MEMS MOEMS 8, 013030 (2009).
[CrossRef]

Xie, H.

L. Wu and H. Xie, J. Micro/Nanolithogr. MEMS MOEMS 8, 013030 (2009).
[CrossRef]

H. Xie, “Full circumferential scanning OCT intravascular imaging probe based on scanning MEMS mirror,” U.S. patent 7,450,244 (November 11, 2008).

Xu, Y.

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Yang, C.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Yaqoob, Z.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

Yu, L.

Zhang, J.

J. Biomed. Opt. (1)

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, J. Biomed. Opt. 11, 063001 (2006).
[CrossRef]

J. Micro/Nanolithogr. MEMS MOEMS (1)

L. Wu and H. Xie, J. Micro/Nanolithogr. MEMS MOEMS 8, 013030 (2009).
[CrossRef]

J. Micromech. Microeng. (1)

Y. Xu, J. Singh, C. S. Premachandran, A. Khairyanto, K. W. S. Chen, N. Chen, C. J. R. Sheppard, and M. Olivo, J. Micromech. Microeng. 18, 125005 (2008).
[CrossRef]

Opt. Express (1)

Opt. Lett. (2)

Phys. Med. Biol. (1)

C. E. Bisaillon, G. Lamouche, R. Maciejko, M. Dufour, and J. P. Monchalin, Phys. Med. Biol. 53, N237 (2008).
[CrossRef] [PubMed]

Other (4)

New Scale Technologies, Inc., http://www.newscaletech.com.

H. Xie, “Full circumferential scanning OCT intravascular imaging probe based on scanning MEMS mirror,” U.S. patent 7,450,244 (November 11, 2008).

E. Regar, T. G. van Leeuwen, and P. W. Serruys, in Design of an OCT Imaging System for Intravascular Applications (Informa Healthcare, 2007), Chap. 1.3.

M. D. Feldman, T. E. Milner, J. H. Oh, E. Kim, K. Kumar, C. Condit, R. Grant, N. Kemp, J. Kim, S. Chen, and L.-H. Han, “OCT using spectrally resolved bandwidth,” U. S. patent application 20110009701 (January 13, 2011).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (4)

Fig. 1
Fig. 1

Scheme of proposed rotary scanning probe.

Fig. 2
Fig. 2

Schematic of mirror head cap. The fiber ball lens is mounted in the center.

Fig. 3
Fig. 3

Rotary fiber probe with a catheter.

Fig. 4
Fig. 4

OCT images of phantom vessel created by rotary probe. (Top) Image in polar coordinates. (Bottom) Image in X Y coordinates.

Metrics