Abstract

For lensless digital in-line holographic microscopy a new state-of-the-art spatial resolution corresponding to an NA of 0.8 is shown based on the tile superposition propagation. The result is proved using a common glass sample carrier with a refraction index of 1.52. Single-shot high-resolution imaging is possible by suppression of coherent reflections in an optimized arrangement using partially coherent laser light illumination.

© 2011 Optical Society of America

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References

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2011 (1)

2010 (5)

2009 (2)

2006 (1)

2004 (1)

1999 (1)

1992 (1)

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

1991 (1)

H.-W. Fink, H. Schmid, H. J. Kreuzer, and A. Wierzbicki, Phys. Rev. Lett. 67, 1543 (1991).
[CrossRef] [PubMed]

1967 (1)

J. W. Goodman and R. W. Lawrence, Appl. Phys. Lett. 11, 77 (1967).
[CrossRef]

1948 (1)

D. Gabor, Nature 161, 777 (1948).
[CrossRef]

Calabuig, A.

Di, J.

Ferraro, P.

Ferreira, C.

Fink, H.-W.

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

H.-W. Fink, H. Schmid, H. J. Kreuzer, and A. Wierzbicki, Phys. Rev. Lett. 67, 1543 (1991).
[CrossRef] [PubMed]

Gabor, D.

D. Gabor, Nature 161, 777 (1948).
[CrossRef]

Garcia, J.

Garcia-Martinez, P.

Garcia-Sucerquia, J.

Goodman, J. W.

J. W. Goodman and R. W. Lawrence, Appl. Phys. Lett. 11, 77 (1967).
[CrossRef]

Graulig, C.

Isikman, S. O.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Jericho, M. H.

Jericho, S. K.

Kanka, M.

Klages, P.

Kreuzer, H. J.

M. Kanka, R. Riesenberg, and H. J. Kreuzer, Opt. Lett. 34, 1162 (2009).
[CrossRef] [PubMed]

J. Garcia-Sucerquia, W. Xu, S. K. Jericho, P. Klages, M. H. Jericho, and H. J. Kreuzer, Appl. Opt. 45, 836(2006).
[CrossRef] [PubMed]

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

H.-W. Fink, H. Schmid, H. J. Kreuzer, and A. Wierzbicki, Phys. Rev. Lett. 67, 1543 (1991).
[CrossRef] [PubMed]

Lawrence, R. W.

J. W. Goodman and R. W. Lawrence, Appl. Phys. Lett. 11, 77 (1967).
[CrossRef]

Meinecke, T.

Micó, V.

Mudanyali, O.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Nakamura, K.

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

Ohzu, H.

Ozcan, A.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Oztoprak, C.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Paturzo, M.

Riesenberg, R.

Sabitov, N.

Schmid, H.

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

H.-W. Fink, H. Schmid, H. J. Kreuzer, and A. Wierzbicki, Phys. Rev. Lett. 67, 1543 (1991).
[CrossRef] [PubMed]

Sencan, I.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Sinzinger, S.

Sun, W.

Takaki, Y.

Tseng, D.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Wierzbicki, A.

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

H.-W. Fink, H. Schmid, H. J. Kreuzer, and A. Wierzbicki, Phys. Rev. Lett. 67, 1543 (1991).
[CrossRef] [PubMed]

Wuttig, A.

Xu, W.

Yaglidere, O.

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Yan, X.

Zalevsky, Z.

Zhao, J.

Appl. Opt. (3)

Appl. Phys. Lett. (1)

J. W. Goodman and R. W. Lawrence, Appl. Phys. Lett. 11, 77 (1967).
[CrossRef]

J. Biomed. Opt. (1)

V. Micó and Z. Zalevsky, J. Biomed. Opt. 15, 046027 (2010).
[CrossRef] [PubMed]

Lab Chip (1)

D. Tseng, O. Mudanyali, C. Oztoprak, S. O. Isikman, I. Sencan, O. Yaglidere, and A. Ozcan, Lab Chip 10, 1787(2010).
[CrossRef] [PubMed]

Nature (1)

D. Gabor, Nature 161, 777 (1948).
[CrossRef]

Opt. Express (2)

Opt. Lett. (4)

Phys. Rev. Lett. (1)

H.-W. Fink, H. Schmid, H. J. Kreuzer, and A. Wierzbicki, Phys. Rev. Lett. 67, 1543 (1991).
[CrossRef] [PubMed]

Ultramicroscopy (1)

H. J. Kreuzer, K. Nakamura, A. Wierzbicki, H.-W. Fink, and H. Schmid, Ultramicroscopy 45, 381 (1992).
[CrossRef]

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Figures (3)

Fig. 1
Fig. 1

Lensless digital in-line holographic microscopy.

Fig. 2
Fig. 2

Multiple reflections between pinhole chip and sample carrier (glass) using light sources with limited temporal coherence. (a) If the pinhole to sample carrier distance is too little, these reflections cause disturbing additional concentric ring systems in the measured hologram (below). (b) By turning the sample carrier upside down, the distance is increased and the reflections become practically incoherent. The measured hologram (below) is free from disturbing interferences.

Fig. 3
Fig. 3

(a)  816 nm PMMA beads ( ± 20 nm ) imaged by an optical microscope (NA 0.75, λ = 470 nm ). (b) Reconstructed DIHM image of the same scene using a highly coherent laser and (c) a partially coherent laser. (d) The same DIHM image after an additional numerical correction of the glass sample carrier. (e) 3D view of the red framed image section in (d). (f) Sectional view for different NAs, as indicated in (e). (g) Pleurosigma angulatum imaged by an optical microscope (NA 0.75, λ = 661 nm ) and (h) the DIHM image with similar quality.

Equations (1)

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z obj l coh < 2 z glass ,

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