Abstract

In this Letter, we report for the first time (to our knowledge) in-vivo volumetric optical coherence microscopy images of skin epidermal cells. We achieved micrometer-class resolution, 2μm laterally and axially, with an acquisition speed of 23K A-scans/s and over 90dB sensitivity to a depth of 1mm by employing a custom, liquid-lens-based, dynamic-focusing objective, a broadband light source, and a custom, astigmatism-corrected Czerny–Turner spectrometer with a high-speed complementary metal-oxide-semiconductor camera.

© 2011 Optical Society of America

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