Abstract

A surface plasmon biosensing technique based on real-time measurement of the spectro-angular reflectance spectrum of a gold surface is presented. A significant improvement in refractive index resolution and drift compensation has been achieved for the spectro-angular technique to demonstrate a biosensing platform that is, in addition, applicable to plasmonic bandgap measurements. Instrumental improvements are detailed and constants for the model bovine serum albumin (BSA):oxacillin bioassay are presented.

© 2011 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. C. J. Alleyne, A. G. Kirk, W. Y. Chien, and P. G. Charette, Opt. Express 16, 19493 (2008).
    [CrossRef] [PubMed]
  2. M. Nakkach, A. Duval, B. Ea-Kim, J. Moreau, and M. Canva1, Opt. Lett. 35, 2209 (2010).
    [CrossRef] [PubMed]
  3. J. Homola, S. S. Yee, and G. Gauglitz, Sens. Actuators B 54, 3 (1999).
    [CrossRef]
  4. M. Piliarik and J. Homola, Opt. Express 17, 16505 (2009).
    [CrossRef] [PubMed]
  5. http://www.cores.utah.edu/interaction/scrubber.html.
  6. X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
    [CrossRef]

2010 (1)

2009 (1)

2008 (1)

2006 (1)

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

1999 (1)

J. Homola, S. S. Yee, and G. Gauglitz, Sens. Actuators B 54, 3 (1999).
[CrossRef]

Alleyne, C. J.

Canva1, M.

Charette, P. G.

Chien, W. Y.

Duval, A.

Ea-Kim, B.

Gauglitz, G.

J. Homola, S. S. Yee, and G. Gauglitz, Sens. Actuators B 54, 3 (1999).
[CrossRef]

Homola, J.

M. Piliarik and J. Homola, Opt. Express 17, 16505 (2009).
[CrossRef] [PubMed]

J. Homola, S. S. Yee, and G. Gauglitz, Sens. Actuators B 54, 3 (1999).
[CrossRef]

Kirk, A. G.

Liu, X.

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

Liu, Z.

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

Moreau, J.

Nakkach, M.

Piliarik, M.

Song, D.

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

Yee, S. S.

J. Homola, S. S. Yee, and G. Gauglitz, Sens. Actuators B 54, 3 (1999).
[CrossRef]

Zhang, H.

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

Zhang, Q.

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

Opt. Express (2)

Opt. Lett. (1)

Sens. Actuators B (2)

J. Homola, S. S. Yee, and G. Gauglitz, Sens. Actuators B 54, 3 (1999).
[CrossRef]

X. Liu, D. Song, Q. Zhang, Z. Liu, and H. Zhang, Sens. Actuators B 117, 188 (2006).
[CrossRef]

Other (1)

http://www.cores.utah.edu/interaction/scrubber.html.

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (4)

Fig. 1
Fig. 1

Schematic of dual channel spectro- angular dispersion curve imaging instrument. Signal and reference channels are interchangeable.

Fig. 2
Fig. 2

Real-time processing of spectro-angular dispersion curves and differential referencing, where n ^ represents refractive index and C is the calibration constant.

Fig. 3
Fig. 3

Influence of reference channel and calibration. Inset illustrates the need to allow the light source, cameras, and temperature compensation to equilibrate; this involves a period no shorter than 70 min.

Fig. 4
Fig. 4

(a) Drift correction in oxacillin binding; (b) binding curves as processed for kinetic analysis; (c) linear calibration for [oxacillin] versus RIU.

Metrics