Abstract

A rapid line-scan confocal imager was developed for functional imaging of the retina. In this imager, an acousto-optic deflector was employed to produce mechanical vibration- and inertia-free light scanning, and a high-speed (68,000 Hz) linear CCD camera was used to achieve subcellular and submillisecond spatiotemporal resolution imaging. Two imaging modalities, i.e., frame-by-frame and line-by-line recording, were validated for the reflected light detection of intrinsic optical signals (IOSs) in visible light stimulus activated frog retinas. Experimental results indicated that fast IOSs were tightly correlated with retinal stimuli and could track visible light flicker stimulus frequency up to at least 2 Hz.

© 2010 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
In vivo confocal imaging of fast intrinsic optical signals correlated with frog retinal activation

Qiu-Xiang Zhang, Rong-Wen Lu, Yang-Guo Li, and Xin-Cheng Yao
Opt. Lett. 36(23) 4692-4694 (2011)

High spatiotemporal resolution imaging of fast intrinsic optical signals activated by retinal flicker stimulation

Yang-Guo Li, Qiu-Xiang Zhang, Lei Liu, Franklin R. Amthor, and Xin-Cheng Yao
Opt. Express 18(7) 7210-7218 (2010)

En face optical coherence tomography of transient light response at photoreceptor outer segments in living frog eyecup

Benquan Wang, Rongwen Lu, Qiuxiang Zhang, Yuqiang Jiang, and Xincheng Yao
Opt. Lett. 38(22) 4526-4529 (2013)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription