Abstract

We have previously developed a new way for nonscanning second-harmonic generation (SHG) microscopy [Opt. Lett.34, 2450 (2009)]. Based on digital holography, this technique captures, in single-shot hologram acquisition, both the amplitude and the phase of a coherent SHG radiation, which makes possible second harmonic phase microscopy. In this work, we present holographic SHG phase microscopy of a label-free biological tissue and discuss its added value to SHG microscopy.

© 2010 Optical Society of America

PDF Article

References

  • View by:
  • |
  • |
  • |

  1. I. Freund and M. Deutsch, Opt. Lett. 11, 94 (1986).
    [CrossRef]
  2. Y. C. Guo, P. P. Ho, H. Savage, D. Harris, P. Sacks, S. Schantz, F. Liu, N. Zhadin, and R. R. Alfano, Opt. Lett. 22, 1323 (1997).
    [CrossRef]
  3. P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
    [CrossRef]
  4. L. Moreaux, O. Sandre, M. Blanchard-Desce, and J. Mertz, Opt. Lett. 25, 320 (2000).
    [CrossRef]
  5. A. Zoumi, A. Yeh, and B. J. Tromberg, Proc. Natl. Acad. Sci. USA 99, 11014 (2002).
  6. W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).
  7. S. J. Lin, R. J. Wu, H. Y. Tan, W. Lo, W. C. Lin, T. H. Young, C. J. Hsu, J. S. Chen, S. H. Jee, and C. Y. Dong, Opt. Lett. 30, 2275 (2005).
    [CrossRef]
  8. L. Fu, X. S. Gan, and M. Gu, Opt. Lett. 30, 385(2005).
    [CrossRef]
  9. D. Ait-Belkacem, A. Gasecka, F. Munhoz, S. Brustlein, and S. Brasselet, Opt. Express 18, 14859 (2010).
    [CrossRef]
  10. P. Xu, E. Kable, C. J. R. Sheppard, and G. Cox, Chinese Optics Letters 8, 213 (2010).
  11. Y. Pu, M. Centurion, and D. Psaltis, Appl. Opt. 47, A103 (2008).
    [CrossRef]
  12. E. Shaffer, N. Pavillon, J. Kühn, and C. Depeursinge, Opt. Lett. 34, 2450 (2009).
    [CrossRef]
  13. E. Shaffer, P. Marquet, and C. Depeursinge, Opt. Express 18, 17392 (2010).
    [CrossRef]
  14. O. Masihzadeh, P. Schlup, and R. A. Bartels, Opt. Express 18, 9840 (2010).
    [CrossRef]
  15. E. Cuche, P. Marquet, and C. Depeursinge, Appl. Opt. 38, 6994 (1999).
    [CrossRef]
  16. B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).
  17. N. Lue, G. Popescu, T. Ikeda, R. Dasari, K. Badizadegan, and M. Feld, Opt. Lett. 31, 2759 (2006).
    [CrossRef]
  18. U. Schnars and W. P. O. Juptner, Meas. Sci. Technol. 13, R85 (2002).
    [CrossRef]
  19. B. Rappaz, F. Charriere, C. Depeursinge, P. J. Magistretti, and P. Marquet, Opt. Lett. 33, 744 (2008).
    [CrossRef]

2010 (4)

2009 (1)

2008 (2)

2006 (2)

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

N. Lue, G. Popescu, T. Ikeda, R. Dasari, K. Badizadegan, and M. Feld, Opt. Lett. 31, 2759 (2006).
[CrossRef]

2005 (2)

2003 (1)

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

2002 (2)

A. Zoumi, A. Yeh, and B. J. Tromberg, Proc. Natl. Acad. Sci. USA 99, 11014 (2002).

U. Schnars and W. P. O. Juptner, Meas. Sci. Technol. 13, R85 (2002).
[CrossRef]

2000 (1)

1999 (2)

P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
[CrossRef]

E. Cuche, P. Marquet, and C. Depeursinge, Appl. Opt. 38, 6994 (1999).
[CrossRef]

1997 (1)

1986 (1)

Ait-Belkacem, D.

Alfano, R. R.

Badizadegan, K.

Bartels, R. A.

Blanchard-Desce, M.

Brasselet, S.

Bredebusch, I.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Brustlein, S.

Campagnola, P. J.

P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
[CrossRef]

Carl, D.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Centurion, M.

Charriere, F.

Chen, J. S.

Christie, R.

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Cox, G.

P. Xu, E. Kable, C. J. R. Sheppard, and G. Cox, Chinese Optics Letters 8, 213 (2010).

Cuche, E.

Dasari, R.

Depeursinge, C.

Deutsch, M.

Domschke, W.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Dong, C. Y.

Feld, M.

Freund, I.

Fu, L.

Gan, X. S.

Gasecka, A.

Gu, M.

Guo, Y. C.

Harris, D.

Ho, P. P.

Hsu, C. J.

Hyman, B. T.

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Ikeda, T.

Jee, S. H.

Juptner, W. P. O.

U. Schnars and W. P. O. Juptner, Meas. Sci. Technol. 13, R85 (2002).
[CrossRef]

Kable, E.

P. Xu, E. Kable, C. J. R. Sheppard, and G. Cox, Chinese Optics Letters 8, 213 (2010).

Kemper, B.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Kühn, J.

Lewis, A.

P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
[CrossRef]

Lin, S. J.

Lin, W. C.

Liu, F.

Lo, W.

Loew, L. M.

P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
[CrossRef]

Lue, N.

Magistretti, P. J.

Marquet, P.

Masihzadeh, O.

Mertz, J.

Moreaux, L.

Munhoz, F.

Nikitin, A. Y.

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Pavillon, N.

Popescu, G.

Psaltis, D.

Pu, Y.

Rappaz, B.

Sacks, P.

Sandre, O.

Savage, H.

Schäfer, M.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Schantz, S.

Schlup, P.

Schnars, U.

U. Schnars and W. P. O. Juptner, Meas. Sci. Technol. 13, R85 (2002).
[CrossRef]

Schnekenburger, J.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Shaffer, E.

Sheppard, C. J. R.

P. Xu, E. Kable, C. J. R. Sheppard, and G. Cox, Chinese Optics Letters 8, 213 (2010).

Tan, H. Y.

Tromberg, B. J.

A. Zoumi, A. Yeh, and B. J. Tromberg, Proc. Natl. Acad. Sci. USA 99, 11014 (2002).

von Bally, G.

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Webb, W. W.

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Wei, M. D.

P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
[CrossRef]

Williams, R. M.

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Wu, R. J.

Xu, P.

P. Xu, E. Kable, C. J. R. Sheppard, and G. Cox, Chinese Optics Letters 8, 213 (2010).

Yeh, A.

A. Zoumi, A. Yeh, and B. J. Tromberg, Proc. Natl. Acad. Sci. USA 99, 11014 (2002).

Young, T. H.

Zhadin, N.

Zipfel, W. R.

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Zoumi, A.

A. Zoumi, A. Yeh, and B. J. Tromberg, Proc. Natl. Acad. Sci. USA 99, 11014 (2002).

Appl. Opt. (2)

Biophys. J. (1)

P. J. Campagnola, M. D. Wei, A. Lewis, and L. M. Loew, Biophys. J. 77, 3341 (1999).
[CrossRef]

Chinese Optics Letters (1)

P. Xu, E. Kable, C. J. R. Sheppard, and G. Cox, Chinese Optics Letters 8, 213 (2010).

J. Biomed. Opt. (1)

B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, and G. von Bally, J. Biomed. Opt. 11, 034005 (2006).

Meas. Sci. Technol. (1)

U. Schnars and W. P. O. Juptner, Meas. Sci. Technol. 13, R85 (2002).
[CrossRef]

Opt. Express (3)

Opt. Lett. (8)

Proc. Natl. Acad. Sci. USA (2)

A. Zoumi, A. Yeh, and B. J. Tromberg, Proc. Natl. Acad. Sci. USA 99, 11014 (2002).

W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, Proc. Natl. Acad. Sci. USA 100, 7075 (2003).

Supplementary Material (1)

» Media 1: JPG (291 KB)     

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Metrics