Ultrabroadband background-free coherent anti-Stokes Raman scattering microscopy based on a compact Er:fiber laser system

Abstract

We demonstrate a scheme for efficient coherent anti-Stokes Raman scattering (CARS) microscopy free of nonresonant background. Our method is based on a compact Er:fiber laser source. Impulsive excitation of molecular resonances is achieved by an $11\mathrm{fs}$ pulse at $1210\mathrm{nm}$. Broadband excitation gives access to molecular resonances from $0{\mathrm{cm}}^{-1}$ up to $4000{\mathrm{cm}}^{-1}$. Time-delayed narrowband probing at $775\mathrm{nm}$ enables sensitive and high-speed spectral detection of the CARS signal free of nonresonant background with a resolution of $10{\mathrm{cm}}^{-1}$.

© 2010 Optical Society of America

Compact coherent anti-Stokes Raman scattering microscope based on a picosecond two-color Er:fiber laser system

Günther Krauss, Tobias Hanke, Alexander Sell, Daniel Träutlein, Alfred Leitenstorfer, Romedi Selm, Martin Winterhalder, and Andreas Zumbusch
Opt. Lett. 34(18) 2847-2849 (2009)

Single-shot interferometric approach to background free broadband coherent anti-Stokes Raman scattering spectroscopy*

Young Jong Lee and Marcus T. Cicerone
Opt. Express 17(1) 123-135 (2009)

Dual-soliton Stokes-based background-free coherent anti-Stokes Raman scattering spectroscopy and microscopy

Kun Chen, Tao Wu, Haoyun Wei, and Yan Li
Opt. Lett. 41(11) 2628-2631 (2016)

Quantitative chemical imaging with background-free multiplex coherent anti-Stokes Raman scattering by dual-soliton Stokes pulses

Kun Chen, Tao Wu, Haoyun Wei, Tian Zhou, and Yan Li
Biomed. Opt. Express 7(10) 3927-3939 (2016)

Triple-frequency symmetric subtraction scheme for nonresonant background suppression in coherent anti-Stokes Raman scattering (CARS) microscopy

Chao Fang, Fake Lu, Wei Zheng, and Zhiwei Huang
Opt. Express 18(15) 15714-15724 (2010)